Tulipalin A
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Tulipalin A
Tulipalin A, also known as α-methylene-γ-butyrolactone, is a naturally occurring compound found in certain flowers such as tulips and alstroemerias. Tulipalin A has the molecular formula C5H6O2 and the CAS registry number 547-65-9. It is an allergen and has been known to cause occupational contact dermatitis, i.e. 'tulip fingers,' in some who are commonly exposed to it such as florists. It has been shown to be synthesized from tuliposide A in response to damage to the plant. When the plant is damaged, tuliposide A is broken down by tuliposide-converting enzymes (TCE) to produce tulipalin A. More recent experiments with this compound have uncovered potential applications for it in the field of polymerization In polymer chemistry, polymerization (American English), or polymerisation (British English), is a process of reacting monomer molecules together in a chemical reaction to form polymer chains or three-dimensional networks. There are many fo .... References {{reflist ...
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Tulip
Tulips are spring-blooming perennial herbaceous bulbiferous geophytes in the ''Tulipa'' genus. Their flowers are usually large, showy, and brightly coloured, generally red, orange, pink, yellow, or white. They often have a different coloured blotch at the base of the tepals, internally. Because of a degree of variability within the populations and a long history of cultivation, classification has been complex and controversial. The tulip is a member of the lily family, Liliaceae, along with 14 other genera, where it is most closely related to '' Amana'', ''Erythronium'', and '' Gagea'' in the tribe Lilieae. There are about 75 species, and these are divided among four subgenera. The name "tulip" is thought to be derived from a Persian word for turban, which it may have been thought to resemble by those who discovered it. Tulips were originally found in a band stretching from Southern Europe to Central Asia, but since the seventeenth century have become widely naturalise ...
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Alstroemeria
''Alstroemeria'' (), commonly called the Peruvian lily or lily of the Incas, is a genus of flowering plants in the family Alstroemeriaceae. They are all native to South America, although some have become naturalized in the United States, Mexico, Australia, New Zealand, Madeira and the Canary Islands. Almost all of the species are restricted to one of two distinct centers of diversity: one in central Chile and southern Argentina, the other in eastern Brazil. Species of ''Alstroemeria'' from Patagonia are winter-growing plants, while those of Brazil are summer growing. All are long-lived Perennial plant, perennials except ''A. graminea'', a diminutive Annual plant, annual from the Atacama Desert of Chile. Description Plants of this genus grow from a cluster of tubers. They send up fertile and sterile stems, the fertile stems of some species reaching in height. The leaves are alternately arranged and Resupination, resupinate, twisted on the petiole (botany), petioles so that t ...
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Allergen
An allergen is an otherwise harmless substance that triggers an allergic reaction in sensitive individuals by stimulating an immune response. In technical terms, an allergen is an antigen that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses. Most humans mount significant immunoglobulin E responses only as a defense against parasitic infections. However, some individuals may respond to many common environmental antigens. This hereditary predisposition is called atopy. In atopic individuals, non-parasitic antigens stimulate inappropriate IgE production, leading to type I hypersensitivity. Sensitivities vary widely from one person (or from one animal) to another. A very broad range of substances can be allergens to sensitive individuals. Examples Allergens can be found in a variety of sources, such as dust mite excretion, pollen, pet dander, or even royal jelly. Food allergies are not as co ...
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Contact Dermatitis
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes are not contagious or life-threatening, but can be very uncomfortable. Contact dermatitis results from either exposure to allergens ( allergic contact dermatitis), or irritants ( irritant contact dermatitis). Allergic contact dermatitis involves a delayed type of hypersensitivity and previous exposure to an allergen to produce a reaction. Irritant contact dermatitis is the most common type and represents 80% of all cases. It is caused by prolonged exposure to irritants, leading to direct injury of the epidermal cells of the skin, which activates an immune response, resulting in an inflammatory cutaneous reaction. Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight. Diagnosis of allergic contact dermati ...
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Polymerization
In polymer chemistry, polymerization (American English), or polymerisation (British English), is a process of reacting monomer molecules together in a chemical reaction to form polymer chains or three-dimensional networks. There are many forms of polymerization and different systems exist to categorize them. In chemical compounds, polymerization can occur via a variety of reaction mechanisms that vary in complexity due to the functional groups present in the reactants and their inherent steric effects. In more straightforward polymerizations, alkenes form polymers through relatively simple radical reactions; in contrast, reactions involving substitution at a carbonyl group require more complex synthesis due to the way in which reactants polymerize. As alkenes can polymerize in somewhat straightforward radical reactions, they form useful compounds such as polyethylene and polyvinyl chloride (PVC), which are produced in high tonnages each year due to their usefulnes ...
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Plant Toxins
A toxin is a naturally occurring poison produced by metabolic activities of living cells or organisms. They occur especially as proteins, often conjugated. The term was first used by organic chemist Ludwig Brieger (1849–1919), derived from '' toxic''. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. They vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Less strict understandings embrace naturally occurring inorganic toxins, such as arsenic. Other understandings embrace synthetic analogs of naturally occurring organic poisons as toxins, and may or may not embrace naturally oc ...
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