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Triacylglycerol Lipase
The enzyme triacylglycerol lipase (also triglyceride lipase, EC 3.1.1.3;systematic name triacylglycerol acylhydrolase) catalyses the hydrolysis of ester linkages of triglycerides: : triacylglycerol + H2O diacylglycerol + a carboxylate These lipases are widely distributed in animals, plants and prokaryotes. This family was also called class 3 lipases as they are only distantly related to other lipase families. Human proteins containing this domain DAGLA; DAGLB; LOC221955; The pancreatic enzyme acts only on an ester-water interface. Nomenclature Other names include ''lipase'', ''butyrinase'', ''tributyrinase'', ''Tween hydrolase'', ''steapsin'', ''triacetinase'', ''tributyrin esterase'', ''Tweenase'', ''amno N-AP'', ''Takedo 1969-4-9'', ''Meito MY 30'', ''Tweenesterase'', ''GA 56'', ''capalase L'', ''triglyceride hydrolase'', ''triolein hydrolase'', ''tween-hydrolyzing esterase'', ''amano CE'', ''cacordase'', ''triglyceridase'', ''triacylglycerol ester hydrolase' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triglycerides
A triglyceride (from ''wikt:tri-#Prefix, tri-'' and ''glyceride''; also TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other vertebrates as well as vegetable fat. They are also present in the blood to enable the bidirectional transference of Adipose tissue, adipose fat and blood glucose from the liver and are a major component of sebum, human skin oils. Many types of triglycerides exist. One specific classification focuses on Saturated and unsaturated compounds, saturated and unsaturated types. Saturated fats have ''no'' C=C groups; unsaturated fats feature one or more C=C groups. Unsaturated fats tend to have a lower melting point than saturated analogues; as a result, they are often liquid at room temperature. Chemical structure The three fatty acids substituents can be the same, but they are usually different. The positions of the three fatty acids a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triacylglycerol
A triglyceride (from ''tri-'' and '' glyceride''; also TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other vertebrates as well as vegetable fat. They are also present in the blood to enable the bidirectional transference of adipose fat and blood glucose from the liver and are a major component of human skin oils. Many types of triglycerides exist. One specific classification focuses on saturated and unsaturated types. Saturated fats have ''no'' C=C groups; unsaturated fats feature one or more C=C groups. Unsaturated fats tend to have a lower melting point than saturated analogues; as a result, they are often liquid at room temperature. Chemical structure The three fatty acids substituents can be the same, but they are usually different. The positions of the three fatty acids are specified using stereospecific numbering as sn-1, sn-2, and sn-3. The c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diacylglycerol
A diglyceride, or diacylglycerol (DAG), is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages. Two possible forms exist, 1,2-diacylglycerols and 1,3-diacylglycerols. Diglycerides are natural components of food fats, though minor in comparison to triglycerides. DAGs can act as surfactants and are commonly used as emulsifiers in processed foods. DAG-enriched oil (particularly 1,3-DAG) has been investigated extensively as a fat substitute due to its ability to suppress the accumulation of body fat; with total annual sales of approximately USD 200 million in Japan since its introduction in the late 1990s till 2009. Production Diglycerides are a minor component of many seed oils and are normally present at ~1–6%; or in the case of cottonseed oil as much as 10%. Industrial production is primarily achieved by a glycerolysis reaction between triglycerides and glycerol. The raw materials for this may be either vegetable oil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carboxylate
In organic chemistry, a carboxylate is the conjugate base of a carboxylic acid, (or ). It is an anion, an ion with negative charge. Carboxylate salts are salts that have the general formula , where M is a metal and ''n'' is 1, 2,.... Carboxylate esters have the general formula (also written as ), where R and R′ are organic groups. Synthesis Carboxylate ions can be formed by deprotonation of carboxylic acids. Such acids typically have p''K''a of less than 5, meaning that they can be deprotonated by many bases, such as sodium hydroxide or sodium bicarbonate. : Resonance stabilization of the carboxylate ion Carboxylic acids easily dissociate into a carboxylate anion and a positively charged hydrogen ion (proton), much more readily than alcohols do (into an alkoxide ion and a proton), because the carboxylate ion is stabilized by resonance. The negative charge that is left after deprotonation of the carboxyl group is delocalized between the two electronegat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
LOC221955
LOC, L.O.C., Loc, LoC, or locs may refer to: Places * Lóc, a village in Sângeorgiu de Pădure, Mureș County, Romania * Lócs, a village in Vas county, Hungary * Line of Contact, meeting place of Western and Eastern Allied forces at the end of World War II in Europe (1945) * Line of Control, a ceasefire line between Indian- and Pakistani-controlled parts of Kashmir (1972–present) * Locwood stop, Hong Kong, MTR station code * Line of Contact (Nagorno-Karabakh) between Armenian and Azerbaijani forces (1994–present) People with the name * L.O.C. (rapper) (born 1979), Danish rapper * Goldie Loc (born 1980), American rapper * Spider Loc (born 1979), American rapper * Tone Lōc (born 1966), American hip-hop artist and director * Laughlin Phillips or Loc (1924–2010), American museum director Arts, entertainment, and media * LOC: Kargil, a 2003 Indian war film. * OG Loc, fictional character in the video game '' Grand Theft Auto: San Andreas'' * '' Steel Battalion: Line o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pancreatic
The pancreas (plural pancreases, or pancreata) is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. Ninety-nine percent of the pancreas is exocrine and 1% is endocrine. As an endocrine gland, it functions mostly to regulate blood sugar levels, secreting the hormones insulin, glucagon, somatostatin and pancreatic polypeptide. As a part of the digestive system, it functions as an exocrine gland secreting pancreatic juice into the duodenum through the pancreatic duct. This juice contains bicarbonate, which neutralizes acid entering the duodenum from the stomach; and digestive enzymes, which break down carbohydrates, proteins and fats in food entering the duodenum from the stomach. Inflammation of the pancreas is known as pancreatitis, with common causes including ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pancreatic Lipase
Pancreatic lipases () are a protein family, family of lipolytic enzymes that hydrolyse ester linkages of triglycerides. Lipases are widely distributed in animals, plants and prokaryotes. At least three tissue-specific isozymes exist in higher vertebrates, pancreatic, hepatic and gastric/lingual. These lipases are closely related to each other and to lipoprotein lipase (), which hydrolyses triglycerides of chylomicrons and very low density lipoproteins (VLDL). Pancreatic lipase contains two protein domains. The one toward the N terminus is an α/β hydrolase, whereas the one toward the C terminus plays a role in binding to colipase, a protein needed in order for the lipase to become activated. The most conserved region in all these proteins is centred on a serine residue which has been shown to participate, with a histidine and an aspartic acid residue, in a charge relay system. Such a region is also present in lipases of prokaryotic origin and in lecithin-cholesterol acyltrans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastric Lipase
Gastric lipase, also known as LIPF, is an enzymatic protein that, in humans, is encoded by the ''LIPF'' gene. Function Gastric lipase is an acidic lipase secreted by the gastric chief cells in the fundic mucosa in the stomach. It has a pH optimum of 3–6. Gastric lipase, together with lingual lipase, comprise the two acidic lipases. These lipases, unlike alkaline lipases (such as pancreatic lipase), do not require bile acid or colipase for optimal enzymatic activity. Acidic lipases make up 30% of lipid hydrolysis occurring during digestion in the human adult, with gastric lipase contributing the most of the two acidic lipases. In neonates, acidic lipases are much more important, providing up to 50% of total lipolytic activity. Gastric lipase hydrolyzes the ester bonds of triglycerides in the stomach. Fatty acids and diacylglycerols are produced from this reaction. The long chain free fatty acids have the ability to prevent gastric lipase from hydrolyzing more triglycerides. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lingual Lipase
Lingual lipase is a member of a family of digestive enzymes called triacylglycerol lipases, EC 3.1.1.3, that use the catalytic triad of aspartate, histidine, and serine to hydrolyze medium and long-chain triglycerides into partial glycerides and free fatty acids. The enzyme, released into the mouth along with the saliva, catalyzes the first reaction in the digestion of dietary lipid, with diglycerides being the primary reaction product. However, due to the unique characteristics of lingual lipase, including a pH optimum 4.5–5.4 and its ability to catalyze reactions without bile salts, the lipolytic activity continues through to the stomach. Enzyme release is signaled by the autonomic nervous system after ingestion, at which time the serous glands under the circumvallate and foliate papillae on the surface of the tongue secrete lingual lipase into the grooves of the papillae, co-localized with fat taste receptors. The hydrolysis of the dietary fats is essential for fat absorpt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EC 3
EC3 can refer to: People * Ethan Carter III (EC3) (born 1983), American professional wrestler Places * EC3, a district in the London EC postcode area Groups, organizations, companies * European Cybercrime Centre * EarthCheck, formerly EC3 Global; international tourism advisory group Transportation * BJEV ''EC3'', a Chinese electric vehicle * KUR ''EC3 class'', a class of steam locomotive * EC-3 radar, Italian WWII radar Other uses * Dolby Digital Plus, also known as EC-3 * Hydrolase enzymes (EC 3); see List of EC numbers (EC 3) See also * ECCC (other) {{Letter-NumberCombDisambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
