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Terpinen-4-ol
Terpinen-4-ol is an isomer of terpineol with the chemical formula C10H18O. A primary constituent of tea tree oil, it is obtained as an extract from the leaves, branches, and bark of '' Melaleuca alternifolia'' Cheel. Despite considerable basic and preliminary clinical research of terpinen-4-ol and tea tree oil, its biological properties and potential for clinical uses have not been established as of 2019. It may be a factor in the contact dermatitis of tea tree oil when used topically. Terpinen-4-ol occurs in ''Juniperus communis'' and is thought to be the reason why this wood is highly resistant to rot. Synthesis Terpinen-4-ol can be synthesized from terpinolene (1) by photooxidation, reduction of the resulting hydroperoxide (2), and selective hydrogenation Hydrogenation is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum. The process is commonly employed to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tea Tree Oil
Tea tree oil, also known as melaleuca oil, is an essential oil with a fresh, camphoraceous odour and a colour that ranges from pale yellow to nearly colourless and clear. It is derived from the leaves of the tea tree, '' Melaleuca alternifolia'', native to southeast Queensland and the northeast coast of New South Wales, Australia. The oil comprises many constituent chemicals, and its composition changes if it is exposed to air and oxidises. Commercial use of tea tree oil began in the 1920s, pioneered by the entrepreneur Arthur Penfold. There is little evidence for the effectiveness of tea tree oil in treating mite-infected crusting of eyelids, although some claims of efficacy exist. In traditional medicine, it may be applied topically in low concentrations for skin diseases, although there is little evidence for efficacy. Tea tree oil is neither a patented product nor an approved drug in the United States, although it has been used in skin care products and is appro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terpineol
Terpineol is any of four isomeric monoterpenoids. Terpenoids are terpene that are modified by the addition of a functional group, in this case, an alcohol. Terpineols have been isolated from a variety of sources such as cardamom, cajuput oil, pine oil, and petitgrain oil. Four isomers exist: α-terpineol, β-terpineol, γ-terpineol, and terpinen-4-ol. β-Terpineol and γ-terpineol differ only by the location of the double bond. Terpineol is usually a mixture of these isomers with α-terpineol as the major constituent. : Terpineol has a pleasant odor similar to lilac and is a common ingredient in perfumes, cosmetics, and flavors. α-Terpineol is one of the two most abundant aroma constituents of lapsang souchong tea; the α-terpineol originates in the pine smoke used to dry the tea. (+)-α-Terpineol is a chemical constituent of skullcap. Synthesis and biosynthesis Although it is naturally occurring, terpineol is commonly manufactured from alpha-pinene, which is hydrated in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extract
An extract (essence) is a substance made by extracting a part of a raw material, often by using a solvent such as ethanol, oil or water. Extracts may be sold as tinctures or absolutes or dried and powdered. The aromatic principles of many spices, nuts, herbs, fruits, etc., and some flowers, are marketed as extracts, among the best known of true extracts being almond, cinnamon, cloves, ginger, lemon, nutmeg, orange, peppermint, pistachio, rose, spearmint, vanilla, violet, rum, and wintergreen. Extraction techniques Most natural essences are obtained by extracting the essential oil from the feedstock, such as blossoms, fruit, and roots, or from intact plants through multiple techniques and methods: * Expression ( juicing, pressing) involves physical extraction material from feedstock, used when the oil is plentiful and easily obtained from materials such as citrus peels, olives, and grapes. * Absorption (steeping, decoction). Extraction is done by soak ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melaleuca Alternifolia
''Melaleuca alternifolia'', commonly known as tea tree, is a species of tree or tall shrub in the myrtle family, Myrtaceae. Endemic to Australia, it occurs in southeast Queensland and the north coast and adjacent ranges of New South Wales where it grows along streams and on swampy flats, and is often the dominant species where it occurs. Description ''Melaleuca alternifolia'' is a small tree that can grow to about with a bushy crown and whitish, papery bark. The leaves are arranged alternately, sometimes scattered or whorled. The leaves are smooth, soft, linear in shape, long, and wide. They are also rich in oil with the glands prominent. Flowers occur in white or cream-colored masses of spikes long over a short period, mostly spring to early summer, and give the tree an appearance of looking fluffy. The small, woody, cup-shaped fruit, in diameter, are scattered along the branches. Taxonomy and naming This species was first formally described in 1905 by Joseph Maiden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basic Research
Basic research, also called pure research, fundamental research, basic science, or pure science, is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques, which can be used to intervene and ''alter'' natural or other phenomena. Though often driven simply by curiosity,"Curiosity creates cures: The value and impact of basic research , National Institute of General Medical Sciences, |
Clinical Research
Clinical research is a branch of medical research that involves people and aims to determine the effectiveness (efficacy) and safety of medications, devices, diagnostic products, and treatment regimens intended for improving human health. These research procedures are designed for the prevention, treatment, diagnosis or understanding of disease symptoms. Clinical research is different from clinical practice: in clinical practice, established treatments are used to improve the condition of a person, while in clinical research, evidence is collected under rigorous study conditions on groups of people to determine the efficacy and safety of a treatment. Description The term "clinical research" refers to the entire process of studying and writing about a drug, a medical device or a form of treatment, which includes conducting interventional studies (clinical trials) or observational studies on human participants. Clinical research can cover any medical method or product from it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contact Dermatitis
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes are not contagious or life-threatening, but can be very uncomfortable. Contact dermatitis results from either exposure to allergens ( allergic contact dermatitis), or irritants ( irritant contact dermatitis). Allergic contact dermatitis involves a delayed type of hypersensitivity and previous exposure to an allergen to produce a reaction. Irritant contact dermatitis is the most common type and represents 80% of all cases. It is caused by prolonged exposure to irritants, leading to direct injury of the epidermal cells of the skin, which activates an immune response, resulting in an inflammatory cutaneous reaction. Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight. Diagnosis of allergic contact dermati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Topical Medication
A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surface area, body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including Cream (pharmaceutical), creams, foams, gels, lotions, and ointments. Many topical medications are epicutaneous, meaning that they are applied directly to the skin. Topical medications may also be insufflation (medicine), inhalational, such as asthma medications, or applied to the surface of tissues other than the skin, such as eye drops applied to the conjunctiva, or ear drops placed in the ear, or medications applied to the surface of a Human tooth, tooth. The word ''topical'' derives from Ancient Greek, Greek wikt:τοπικός, τοπικός ''topikos'', "of a place". Justification Topical drug delivery is a route of administering drugs via the Human skin, skin to provide topical therapeutic effects. As sk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Juniperus Communis
''Juniperus communis'', the common juniper, is a species of small tree or shrub in the cypress family Cupressaceae. An evergreen conifer, it has the largest geographical range of any woody plant, with a circumpolar distribution throughout the cool temperate Northern Hemisphere. Description ''Juniperus communis'' is highly variable in form, ranging from —rarely —tall to a low, often prostrate spreading shrub in exposed locations. It has needle-like leaves in whorls of three; the leaves are green, with a single white stomatal band on the inner surface. It never attains the scale-like adult foliage of other members of the genus. It is dioecious, with male and female cones on separate plants so requiring wind pollination to transfer pollen from male to female cones. Male trees or shrubs naturally live longer than female trees or shrubs; a male tree or shrub can live more than 2000 years.Lena K. Ward, The Conservation of Juniper: Longevity and Old Age, Journal of Applied Ecology, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Decomposition
Decomposition is the process by which dead organic substances are broken down into simpler organic or inorganic matter such as carbon dioxide, water, simple sugars and mineral salts. The process is a part of the nutrient cycle and is essential for recycling the finite matter that occupies physical space in the biosphere. Bodies of living organisms begin to decompose shortly after death. Although no two organisms decompose in the same way, they all undergo the same sequential stages of decomposition. Decomposition can be a gradual process for organisms that have extended periods of dormancy. One can differentiate ''abiotic'' decomposition from ''biotic'' decomposition ( biodegradation); the former means "the degradation of a substance by chemical or physical processes", e.g., hydrolysis; the latter means "the metabolic breakdown of materials into simpler components by living organisms", typically by microorganisms. Animals, such as earthworms, also help decompose the organ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terpinolene
The terpinenes are a group of isomeric hydrocarbons that are classified as monoterpenes. They each have the same molecular formula and carbon framework, but they differ in the position of carbon-carbon double bonds. α-Terpinene has been isolated from cardamom and marjoram oils, and from other natural sources. β-Terpinene has no known natural source but has been prepared from sabinene. γ-Terpinene and δ-terpinene (also known as terpinolene) have been isolated from a variety of plant sources. They are all colorless liquids with a turpentine-like odor. Production and uses α-Terpinene is produced industrially by acid-catalyzed rearrangement of α-pinene. It has perfume and flavoring properties but is mainly used to confer pleasant odor to industrial fluids. Hydrogenation gives the saturated derivative P-Menthane, ''p''-menthane. Biosynthesis of α-terpinene The biosynthesis of α-terpinene and other terpenoids starts with the isomerization of geranyl pyrophosphate to lina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
