Tehaunine
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Tehaunine
Tehaunine, or tehuanine, also known as 5,6,7-trimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, is a tetrahydroisoquinoline and cyclized phenethylamine alkaloid found in ''Pachycereus pringlei'' and other cacti. See also * Substituted tetrahydroisoquinoline * Isomescaline Isomescaline (2,3,4-trimethoxyphenethylamine) is a lesser-known compound based on a well-known psychedelic drug. It is an isomer of mescaline, as well as an analog of TIM-2, TIM-3, and TIM-4. Isomescaline was first synthesized by Alexander Sh ... (2,4,5-trimethoxyphenethylamine) * ''Pachycereus pringlei'' § Constituents and biological effects References External links Tehuanine - Isomer Design Methoxyphenethylamines Methyl compounds Tetrahydroisoquinoline alkaloids {{Alkaloid-stub ...
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Pachycereus Pringlei
''Pachycereus pringlei'' (also known as Mexican giant cardon or elephant cactus) is a species of large cactus native to northwestern Mexico, in the states of Baja California, Baja California Sur, and Sonora. It is commonly known as ''cardón'', a name derived from the Spanish word ''cardo'', meaning "thistle"; additionally, it is often referred to as sabueso (or “bloodhound”), which is possibly an early Spanish interpretation of the native Seri term for the plant, xaasj. Large stands of this cactus still exist, but many have been destroyed as land has been cleared for cultivation in Sonora. Climate change will likely impact the future distribution of numerous plant species, including ''Pachycereus pringlei,'' which can be attributed to alterations in precipitation and temperature. The cactus fruits were always an important food for the Seri people, in Sonora; the dried cactus columns themselves could be used for construction purposes, as well as for firewood.* A symbiotic ...
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Substituted Tetrahydroisoquinoline
A substituted tetrahydroisoquinoline is a tetrahydroisoquinoline with one or more chemical substituents. Many simple tetrahydroisoquinoline alkaloids related to mescaline are known and occur naturally in cactus species such as peyote (''Lophophora williamsii'') and ''Pachycereus pringlei'' among many others. Simple tetrahydroisoquinolines may be thought of as cyclized phenethylamines. As an example, anhalinine may be thought of as a cyclic compound, cyclized structural analog, analogue of mescaline. The simple tetrahydroisoquinolines are analogous in concept to the substituted β-carboline, β-carbolines and harmala alkaloids, which can be considered cyclized analogues of substituted tryptamine, tryptamines. Some of the simple tetrahydroisoquinolines, for instance pellotine, are known to be pharmacology, pharmacologically active, although none are known to have hallucinogenic activity. Known activities of simple tetrahydroisoquinolines include sedative and hypnotic effects, monoam ...
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Cyclized Phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents. Phenylethylamines are also generally found to be central nervous system stimulants with many also being entactogens/empathogens, and hallucinogens. Structural classification The structural formula of any substituted phenethylamine contains a phenyl ring that is joined to an amino (NH) group via a two-carbon sidechain. Hence, any substituted phenethylamine can be classified according to the substitution of hydrogen (H) atoms on phenethylamine's phenyl ring, sidechain, or amino group with a specific group of atoms. Several classes of substances can be considered phenylethylamine derivatives such as Substituted amphetamines, ...
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Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ...
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Cacti
A cactus (: cacti, cactuses, or less commonly, cactus) is a member of the plant family Cactaceae (), a family of the order Caryophyllales comprising about 127 genera with some 1,750 known species. The word ''cactus'' derives, through Latin, from the Ancient Greek word (''káktos''), a name originally used by Theophrastus for a spiny plant whose identity is now not certain. Cacti occur in a wide range of shapes and sizes. They are native to the Americas, ranging from Patagonia in the south to parts of western Canada in the north, with the exception of '' Rhipsalis baccifera'', which is also found in Africa and Sri Lanka. Cacti are adapted to live in very dry environments, including the Atacama Desert, one of the driest places on Earth. Because of this, cacti show many adaptations to conserve water. For example, almost all cacti are succulents, meaning they have thickened, fleshy parts adapted to store water. Unlike many other succulents, the stem is the only part of most cacti ...
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Keeper Trout & Friends
Keeper Trout (born October 1957), also known as Keeper of the Trout, is an American independent scholar in the area of psychedelics and psychedelic plants, especially cacti. He is variously described as an author, photographer, ethnobotanist, archivist, and conservationist. Trout first became interested in the psychedelic experience in 1972 when he was 14years old. He studied chemistry and microbiology at university in Texas. Trout worked as a lapidarist but eventually was unable to continue doing this work due having come down with encephalitis which had led to unilateral blindness and loss of his depth perception. In 1991, he pivoted direction and started working more publicly in the area of psychedelics. In 1993, he met Alexander and Ann Shulgin and others at a psychedelic conference and they encouraged him to start writing. He has since written numerous books and other publications on psychedelic plants and alkaloids, including his notable ''Trout's Notes'' series. His book ...
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Isomescaline
Isomescaline (2,3,4-trimethoxyphenethylamine) is a lesser-known compound based on a well-known psychedelic drug. It is an isomer of mescaline, as well as an analog of TIM-2, TIM-3, and TIM-4. Isomescaline was first synthesized by Alexander Shulgin. In his book ''PIHKAL'', it is suggested that any potentially active dose would be "greater than 400 mg". Despite its structural similarity to mescaline, isomescaline has produced no effects in humans. Very little data exists about the pharmacological properties, metabolism, and toxicity of isomescaline. See also * Substituted mescaline analogue A substituted mescaline analogue, also known as a scaline and typically but not always a 4-substituted 3,5-dimethoxyphenethylamine, is an analogue of the phenethylamine serotonergic psychedelic mescaline (3,4,5-trimethoxyphenethylamine). Other ... References Phenol ethers Scalines {{Psychoactive-stub ...
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Methoxyphenethylamines
Methoxyphenethylamine, or monomethoxyphenethylamine, may refer to: * 2-Methoxyphenethylamine (2-MPEA) * 3-Methoxyphenethylamine (3-MPEA) * 4-Methoxyphenethylamine (4-MPEA) See also * Substituted methoxyphenethylamine * Dimethoxyphenethylamine * Trimethoxyphenethylamine * Methoxyamphetamine * Dimethoxyamphetamine * Trimethoxyamphetamine {{Chemistry index Methoxyphenethylamines ...
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Methyl Compounds
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula ). In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bonded to the rest of the molecule by a single covalent bond (), it can be found on its own in any of three forms: methanide anion (), methylium cation () or methyl radical (). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed. Methyl cation, anion, and radical Methyl cation The methylium cation () exists in the gas phase, but is otherwise not encountered. Some compounds are considered to be sources of the cation, and this simplification is used pervasively in organic chemistry. For exampl ...
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