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Tartrolon
Tartrolons are a group of boron-containing macrolide antibiotics discovered in 1994 from the culture broth of the Myxobacteria, myxobacterium ''Sorangium cellulosum''. Two variants of tartrolons, A and B, were identified. Tartrolon B contains a boron atom, while tartrolon A does not. Discovery In a study publishied in 1994, the producing organism, Sorangium cellulosum strain ''So ce 678'', was isolated by a group of German scientists (Dietmar Schummer, Herbert Irschik, Hans Reichenbach, Gerhard Höfle) from a soil sample collected near Braunschweig in 1990, as Antibiotic, antibiotics of the macrolide group. Synthesis was achieved by fermentation in the presence of the adsorber resin XAD-16. Adsorber resin is a type of synthetic polymer used to selectively extract and purify target molecules from solutions. These findings were confirmed by a subsequent study, in 1995, where the strain was grown on a medium containing potato starch, yeast extract, defatted soja meal, glucose-H2O, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boron
Boron is a chemical element; it has symbol B and atomic number 5. In its crystalline form it is a brittle, dark, lustrous metalloid; in its amorphous form it is a brown powder. As the lightest element of the boron group it has three valence electrons for forming covalent bonds, resulting in many compounds such as boric acid, the mineral sodium borate, and the ultra-hard crystals of boron carbide and boron nitride. Boron is synthesized entirely by cosmic ray spallation and supernovas and not by stellar nucleosynthesis, so it is a low-abundance element in the Solar System and in the Earth's crust. It constitutes about 0.001 percent by weight of Earth's crust. It is concentrated on Earth by the water-solubility of its more common naturally occurring compounds, the borate minerals. These are mined industrially as evaporites, such as borax and kernite. The largest known deposits are in Turkey, the largest producer of boron minerals. Elemental boron is found in smal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boromycin
Boromycin is a bacteriocidal polyether- macrolide antibiotic. It was initially isolated from the '' Streptomyces antibioticus'', and is notable for being the first natural product found to contain the element boron. It is effective against most gram-positive bacteria, but is ineffective against gram-negative bacteria. Boromycin kills bacteria by negatively affecting the cytoplasmic membrane, resulting in the loss of potassium ions from the cell. Boromycin has not been approved as a drug for medical use. Discovery Boromycin was discovered by the scholars of the Institute for Special Botany and Organic Chemical Laboratories at the Swiss Federal Institute of Technology, Zurich, Switzerland, who, in 1967, published a study in as an article called "Metabolic products of microorganisms" in the '' Helvetica Chimica Acta'' journal. In this article, the authors described that a new strain of '' Streptomyces antibioticus'' produces a novel antibiotic which was the first boron-containing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erlenmeyer Flask
An Erlenmeyer flask, also known as a conical flask (British English) or a titration flask, is a type of laboratory flask with a flat bottom, a conical body, and a cylindrical neck. It is named after the German chemist Emil Erlenmeyer (1825–1909), who invented it in 1860. Erlenmeyer flasks have wide bases and narrow necks. They may be graduated, and often have spots of ground glass or Vitreous enamel, enamel where they can be labeled with a pencil. It differs from the beaker (glassware), beaker in its tapered body and narrow neck. Depending on the application, they may be constructed from glass or plastic, in a wide range of volumes. The mouth of the Erlenmeyer flask may have a beaded lip that can be bung, stoppered or covered. Alternatively, the neck may be fitted with ground glass or other connector for use with more specialized stoppers or attachment to other apparatus. A Büchner flask is a common design modification for filtration under vacuum. Uses In chemistry The sl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbial Ecology
Microbial ecology (or environmental microbiology) is a discipline where the interaction of Microorganism, microorganisms and their environment are studied. Microorganisms are known to have important and harmful ecological relationships within their species and other species. Many scientists have studied the relationship between nature and microorganisms: Martinus Beijerinck, Sergei Winogradsky, Louis Pasteur, Robert Koch, Lorenz Hiltner, Dionicia Gamboa and many more; to understand the specific roles that these microorganisms have in biological and chemical pathways and how microorganisms have evolved. Currently, there are several types of biotechnologies that have allowed scientists to analyze the biological/chemical properties of these microorganisms also. Many of these microorganisms have been known to form different symbiotic relationships with other organism, organisms in their environment. Some symbiotic relationships include Mutualism (biology), mutualism, commensalism, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Listeria Monocytogenes
''Listeria monocytogenes'' is the species of pathogenic bacteria that causes the infection listeriosis. It is a facultative anaerobic bacterium, capable of surviving in the presence or absence of oxygen. It can grow and reproduce inside the host's cells and is one of the most virulent foodborne pathogens. Twenty to thirty percent of foodborne listeriosis infections in high-risk individuals may be fatal. In the European Union, listeriosis continues an upward trend that began in 2008, causing 2,161 confirmed cases and 210 reported deaths in 2014, 16% more than in 2013. In the EU, listeriosis mortality rates also are higher than those of other foodborne pathogens. Responsible for an estimated 1,600 illnesses and 260 deaths in the United States annually, listeriosis ranks third in total number of deaths among foodborne bacterial pathogens, with fatality rates exceeding even ''Salmonella'' spp. and ''Clostridium botulinum''. Named for Joseph Lister, ''Listeria monocytogenes'' is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aplasmomycin
Aplasmomycin is an antibiotic with antimalarial activity isolated from ''Streptomycete Streptomycetaceae is a family of the order Streptomycetales. It includes the important genus ''Streptomyces''. This was the original source of many antibiotics, namely streptomycin, the first antibiotic against tuberculosis. Genomics Sequence al ...''. References Antibiotics Antimalarial agents Tetrahydroxyborate esters {{organic-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gram-positive Bacteria
In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. The Gram stain is used by microbiologists to place bacteria into two main categories, gram-positive (+) and gram-negative (−). Gram-positive bacteria have a thick layer of peptidoglycan within the cell wall, and gram-negative bacteria have a thin layer of peptidoglycan. Gram-positive bacteria retain the crystal violet stain used in the test, resulting in a purple color when observed through an optical microscope. The thick layer of peptidoglycan in the bacterial cell wall retains the stain after it has been fixed in place by iodine. During the decolorization step, the decolorizer removes crystal violet from all other cells. Conversely, gram-negative bacteria cannot retain the violet stain after the decolorization step; alcohol used in this stage ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Tetraborate
The BORAX Experiments were a series of safety experiments on boiling water reactor, boiling water nuclear reactors conducted by Argonne National Laboratory in the 1950s and 1960s at the National Reactor Testing Station in eastern Idaho.Light Water Reactor Technology Development Argonne National Laboratory They were performed using the five BORAX reactors that were designed and built by Argonne. BORAX-III was the first nuclear reactor to supply electrical power to the North American power transmission grid, grid in the United States in 1955. Evolution of BORAX This series of tests began in 1952 with the construction of the BORAX-I nuclear reactor. BORAX-I experiment proved that a reactor using direct boiling water reactor, boiling of water would be practical, ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Revolutions Per Minute
Revolutions per minute (abbreviated rpm, RPM, rev/min, r/min, or r⋅min−1) is a unit of rotational speed (or rotational frequency) for rotating machines. One revolution per minute is equivalent to hertz. Standards ISO 80000-3:2019 defines a physical quantity called ''rotation'' (or ''number of revolutions''), dimensionless, whose instantaneous rate of change is called ''rotational frequency'' (or ''rate of rotation''), with units of reciprocal seconds (s−1). A related but distinct quantity for describing rotation is ''angular frequency'' (or ''angular speed'', the magnitude of angular velocity), for which the SI unit is the radian per second (rad/s). Although they have the same dimensions (reciprocal time) and base unit (s−1), the hertz (Hz) and radians per second (rad/s) are special names used to express two different but proportional ISQ quantities: frequency and angular frequency, respectively. The conversions between a frequency and an angular frequency ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioreactor
A bioreactor is any manufactured device or system that supports a biologically active environment. In one case, a bioreactor is a vessel in which a chemical reaction, chemical process is carried out which involves organisms or biochemistry, biochemically active chemical substance, substances derived from such organisms. This process can either be Aerobic organism, aerobic or Anaerobic organism, anaerobic. These bioreactors are commonly cylindrical, ranging in size from litres to cubic metres, and are often made of stainless steel. It may also refer to a device or system designed to grow Cell (biology), cells or Biological tissue, tissues in the context of cell culture. These devices are being developed for use in tissue engineering or biochemical engineering, biochemical/bioprocess engineering, bioprocess engineering. On the basis of mode of operation, a bioreactor may be classified as batch reactor, batch, fed-batch, fed batch or continuous reactor, continuous (e.g. a continuous s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Macrolide
Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. Macrolides belong to the polyketide class of natural products. Some macrolides have antibiotic or antifungal activity and are used as pharmaceutical drugs. Rapamycin is also a macrolide and was originally developed as an antifungal, but has since been used as an immunosuppressant drug and is being investigated as a potential longevity therapeutic. Macrolides are a diverse group with many members of very different properties: * Macrolides with 14-, 15-, or 16-membered rings and two attached sugar molecules are antibiotics that bind to bacterial ribosomes, the key representative being erythromycin. The term "macrolide antibiotics" tend to refer to just this class. * Some macrolides with very large (20+ membered) rings are immunosuppresants, the prototypical one being rapamycin. * Some 23-membered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Potato Starch
Potato starch is starch extracted from potatoes. The cells of the root tubers of the potato plant contain leucoplasts (starch grains). To extract the starch, the potatoes are crushed, and the starch grains are released from the destroyed cells. The starch is then left to settle out of solution or separated by Hydrocyclone, hydrocyclones, then dried to powder. Potato starch contains typical large oval spherical granules ranging in size from 5 to 100 Micrometre, μm. Potato starch is a refined starch, containing minimal protein or fat. This gives the powder a clear white colour, and the cooked starch typical characteristics of neutral taste, good clarity, high binding strength, long texture, and minimal tendency to foaming or yellowing of the solution. Potato starch contains approximately 800 Parts per million, ppm phosphate bound to the starch; this increases the viscosity and gives the solution a slightly anionic character, a low starch gelatinization, gelatinisation temperat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
