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Systems Biomedicine
Systems biomedicine, also called systems biomedical science, is the application of systems biology to the understanding and modulation of developmental and pathological processes in humans, and in animal and cellular models. Whereas systems biology aims at modeling exhaustive networks of interactions (with the long-term goal of, for example, creating a comprehensive computational model of the cell), mainly at intra-cellular level, systems biomedicine emphasizes the multilevel, hierarchical nature of the models (molecule, organelle, cell, tissue, organ, individual/genotype, environmental factor, population, ecosystem) by discovering and selecting the key factors at each level and integrating them into models that reveal the global, emergent behavior of the biological process under consideration. Such an approach will be favorable when the execution of all the experiments necessary to establish exhaustive models is limited by time and expense (e.g., in animal models) or basic ethics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rudi Balling
Rudi Balling (born 17 October 1953 in Daun, Rhineland-Palatinate) is a German geneticist. He is the founding director of the Luxembourg Centre for Systems Biomedicine at the University of Luxembourg (2009-2021) He has served as president of the International Mammalian Genome Society (IMGS, 2001–2002) and as co-editor of the ''Annual Review of Nutrition'' since 2018. In 2016 Balling received Luxembourg's Ordre de Mérite (Commandeur) from Prime Minister Xavier Bettel. Biography Following his abitur (1972) at the Geschwister-Scholl Gymnasium in Daun, Germany and military service, Rudi Balling studied nutritional science at the University of Bonn, Germany from 1974 - 1981. He held a Fulbright scholarship from 1978 - 1979 at Washington State University in Pullman, Washington, USA where he studied animal nutrition. Balling received a master's degree from Washington State in 1980 and a Diploma in Human Nutrition from the University of Bonn in 1981. He was a DAAD-Scholar Laborat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. This multifaceted research domain necessitates the collaborative efforts of chemists, biologists, mathematicians, physicists, and engineers to decipher the biology of intricate living systems by merging various quantitative molecular measurements with carefully constructed mathematical models. It represents a comprehensive method for comprehending the complex relationships within biological systems. In contrast to conventional biological studies that typically center on isolated elements, systems biology seeks to combine different biological data to create models that illustrate and elucidate the dynamic interactions with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emergence
In philosophy, systems theory, science, and art, emergence occurs when a complex entity has properties or behaviors that its parts do not have on their own, and emerge only when they interact in a wider whole. Emergence plays a central role in theories of integrative levels and of complex systems. For instance, the phenomenon of life as studied in biology is an emergent property of chemistry and physics. In philosophy, theories that emphasize emergent properties have been called emergentism. In philosophy Philosophers often understand emergence as a claim about the etiology of a system's properties. An emergent property of a system, in this context, is one that is not a property of any component of that system, but is still a feature of the system as a whole. Nicolai Hartmann (1882–1950), one of the first modern philosophers to write on emergence, termed this a ''categorial novum'' (new category). Definitions This concept of emergence dates from at least the time of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Medicine
Systems medicine is an interdisciplinary field of study that looks at the systems of the human body as part of an integrated whole, incorporating biochemical, physiological, and environment interactions. Systems medicine draws on systems science and systems biology, and considers complex interactions within the human body in light of a patient's genomics, behavior and environment. The earliest uses of the term ''systems medicine'' appeared in 1992, in an article on systems medicine and pharmacology by T. Kamada. An important topic in systems medicine and systems biomedicine is the development of computational models that describe disease progression and the effect of therapeutic interventions. More recent approaches include the redefinition of disease phenotypes based on common mechanisms rather than symptoms. These provide then therapeutic targets including network pharmacology and drug repurposing. Since 2018, there is a dedicated scientific journal, ''Systems Medicine''. F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. This multifaceted research domain necessitates the collaborative efforts of chemists, biologists, mathematicians, physicists, and engineers to decipher the biology of intricate living systems by merging various quantitative molecular measurements with carefully constructed mathematical models. It represents a comprehensive method for comprehending the complex relationships within biological systems. In contrast to conventional biological studies that typically center on isolated elements, systems biology seeks to combine different biological data to create models that illustrate and elucidate the dynamic interactions with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Landes Bioscience
Landes Bioscience is an Austin, Texas-based publisher of bioscience journals. ''Cell Cycle'', one of its first two journals, achieved the highest percent increase in total citations in molecular biology and genetics for the period of July–August 2007, with 1490 papers cited 6228 times. It was acquired by Taylor & Francis Taylor & Francis Group is an international company originating in the United Kingdom that publishes books and academic journals. Its parts include Taylor & Francis, CRC Press, Routledge, F1000 (publisher), F1000 Research and Dovepress. It i ... in June 2014. See also * Journals published by Landes Bioscience References External links * {{Authority control Publishing companies of the United States Companies based in Austin, Texas Publishing companies established in 1997 1997 establishments in Texas Academic publishing companies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oregon Health And Science University
Oregon Health & Science University (OHSU) is a public research university focusing primarily on health sciences with a main campus, including two hospitals, in Portland, Oregon. The institution was founded in 1887 as the University of Oregon Medical Department and later became the University of Oregon Medical School. In 1974, the campus became an independent, self-governed institution called the University of Oregon Health Sciences Center, combining state dentistry, medicine, nursing, and public health programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute (OGI), in Hillsboro. The university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University in Corvallis. It is designated as a "Special Focus – Research Institution" according to the Carnegie Classification. History The Willamette University School of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Luxembourg
The University of Luxembourg (French language, French: ''Université du Luxembourg''; German language, German: ''Universität Luxemburg''; Luxembourgish language, Luxembourgish: ''Universitéit Lëtzebuerg'') is a Public university, public research university in Luxembourg. History The University of Luxembourg was founded in 2003 by combining four existing education and research institutes: the Centre universitaire, Institut supérieur d'études et de recherches pédagogiques, Institut supérieur de technologie, and Institut d'études éducatives et sociales. The university is the only public university in Luxembourg. Description The university has three campuses: the Belval, Luxembourg, Belval Campus, the Kirchberg, Luxembourg, Kirchberg Campus, and the Limpertsberg Campus. The university is governed by a board of governors, a rector, and a university council. The current Rector (academia), rector of the University of Luxembourg is Jens Kreisel. Academics The universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Institute Of Oncology
The European Institute of Oncology (, IEO) is a non-profit private-law comprehensive cancer centre located in Milan, Italy. It serves as a clinic, a research centre, and a training institution. IEO is a member of EU-LIFE, an alliance of leading life science research centres in Europe. The European Institute of Oncology works on the prevention, diagnosis and treatment of cancer by developing clinical and scientific research coupled with organisation and management. It provides a professional network for its members. History The European Institute of Oncology was founded by Umberto Veronesi, who developed a new model for health and advanced research in the international oncology field. The institute was inaugurated in May 1994 and is currently managed by Division and Unit Directors from eight European countries. The Institute became a research hospital and treatment centre (IRCCS or ) through the Ministerial Decree issued in January 1996. The European Institute of Oncology provide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ecosystem
An ecosystem (or ecological system) is a system formed by Organism, organisms in interaction with their Biophysical environment, environment. The Biotic material, biotic and abiotic components are linked together through nutrient cycles and energy flows. Ecosystems are controlled by external and internal Environmental factor, factors. External factors—including climate—control the ecosystem's structure, but are not influenced by it. By contrast, internal factors control and are controlled by ecosystem processes; these include decomposition, the types of species present, root competition, shading, disturbance, and succession. While external factors generally determine which Resource (biology), resource inputs an ecosystem has, their availability within the ecosystem is controlled by internal factors. Ecosystems are wikt:dynamic, dynamic, subject to periodic disturbances and always in the process of recovering from past disturbances. The tendency of an ecosystem to remain clo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Model
A computational model uses computer programs to simulate and study complex systems using an algorithmic or mechanistic approach and is widely used in a diverse range of fields spanning from physics, engineering, chemistry and biology to economics, psychology, cognitive science and computer science. The system under study is often a complex nonlinear system for which simple, intuitive analytical solutions are not readily available. Rather than deriving a mathematical analytical solution to the problem, experimentation with the model is done by adjusting the parameters of the system in the computer, and studying the differences in the outcome of the experiments. Operation theories of the model can be derived/deduced from these computational experiments. Examples of common computational models are weather forecasting models, earth simulator models, flight simulator models, molecular protein folding models, Computational Engineering Models (CEM), and neural network models. Se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population
Population is a set of humans or other organisms in a given region or area. Governments conduct a census to quantify the resident population size within a given jurisdiction. The term is also applied to non-human animals, microorganisms, and plants, and has specific uses within such fields as ecology and genetics. Etymology The word ''population'' is derived from the Late Latin ''populatio'' (a people, a multitude), which itself is derived from the Latin word ''populus'' (a people). Use of the term Social sciences In sociology and population geography, population refers to a group of human beings with some predefined feature in common, such as location, Race (human categorization), race, ethnicity, nationality, or religion. Ecology In ecology, a population is a group of organisms of the same species which inhabit the same geographical area and are capable of Sexual reproduction, interbreeding. The area of a sexual population is the area where interbreeding is possi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
