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Surgical Site Infection
A surgical site infection (SSI) develop when bacteria infiltrate the body through surgical incisions. These bacteria may come from the patient's own skin, the surgical instruments, or the environment in which the procedure is performed. An infection is designated as an SSI if it develops at the site of a surgical wound, either because of contamination during surgery or as a result of postoperative complications. For the infection to be classified as an SSI, it should occur within 30 days after surgery or within 1 year if an implant is involved. Surgical site infections that are limited to the skin and subcutaneous tissues are classified as superficial incisional SSIs. These infections are the most common type, accounting for more than 50% of all reported surgical site infections. Symptoms The symptoms of a surgical site infection (SSI) can vary depending on the severity and type of infection. Common signs include redness and pain around the area of the surgical wound. A cloudy ...
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Bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, Hot spring, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the nitrogen fixation, fixation of nitrogen from the Earth's atmosphere, atmosphere. The nutrient cycle includes the decomposition of cadaver, dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, suc ...
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Organ (biology)
In a multicellular organism, an organ is a collection of Tissue (biology), tissues joined in a structural unit to serve a common function. In the biological organization, hierarchy of life, an organ lies between Tissue (biology), tissue and an organ system. Tissues are formed from same type Cell (biology), cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The Gastrointestinal tract, intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma (tissue), stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerve t ...
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Microbial Ecology
Microbial ecology (or environmental microbiology) is a discipline where the interaction of Microorganism, microorganisms and their environment are studied. Microorganisms are known to have important and harmful ecological relationships within their species and other species. Many scientists have studied the relationship between nature and microorganisms: Martinus Beijerinck, Sergei Winogradsky, Louis Pasteur, Robert Koch, Lorenz Hiltner, Dionicia Gamboa and many more; to understand the specific roles that these microorganisms have in biological and chemical pathways and how microorganisms have evolved. Currently, there are several types of biotechnologies that have allowed scientists to analyze the biological/chemical properties of these microorganisms also. Many of these microorganisms have been known to form different symbiotic relationships with other organism, organisms in their environment. Some symbiotic relationships include Mutualism (biology), mutualism, commensalism, a ...
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Pathogen
In biology, a pathogen (, "suffering", "passion" and , "producer of"), in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a Germ theory of disease, germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or Transmission (medicine), transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time ...
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Escherichia Coli
''Escherichia coli'' ( )Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. is a gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus '' Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are part of the normal microbiota of the gut, where they constitute about 0.1%, along with other facultative anaerobes. These bacteria are mostly harmless or even beneficial to humans. For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by harmful pathogenic bacteria. These mutually beneficial relationships between ''E. coli'' and humans are a type of mutualistic biological relationship—where both the humans and the ''E. coli'' are benefitting each other. ''E. coli'' is expelled into the environment within fecal matter. The bacterium grows massi ...
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Enterococcus Faecalis
''Enterococcus faecalis'' – formerly classified as part of the group D '' Streptococcus,'' is a Gram-positive, commensal bacterium naturally inhabiting the gastrointestinal tracts of humans. Like other species in the genus '' Enterococcus'', ''E. faecalis'' is found in healthy humans and can be used as a probiotic. The probiotic strains such as Symbioflor1 and EF-2001 are characterized by the lack of specific genes related to drug resistance and pathogenesis. Despite its commensal role, ''E. faecalis'' is an opportunistic pathogen capable of causing severe infections, especially in the nosocomial (hospital) settings. ''Enterococcus'' spp. is among the leading causes of healthcare-associated infections ranging from endocarditis to urinary tract infections (UTIs). Hospital-acquired UTIs are associated with catheterization because catheters provide an ideal surface for biofilm formation, allowing ''E. faecalis'' to adhere, persist, and evade both the immune response and antibiot ...
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Staphylococci
''Staphylococcus'', from Ancient Greek σταφυλή (''staphulḗ''), meaning "bunch of grapes", and (''kókkos''), meaning "kernel" or " Kermes", is a genus of Gram-positive bacteria in the family Staphylococcaceae from the order Bacillales. Under the microscope, they appear spherical ( cocci), and form in grape-like clusters. ''Staphylococcus'' species are facultative anaerobic organisms (capable of growth both aerobically and anaerobically). The name was coined in 1880 by Scottish surgeon and bacteriologist Alexander Ogston (1844–1929), following the pattern established five years earlier with the naming of '' Streptococcus''. It combines the prefix "staphylo-" (from ), and suffixed by the (from ). Staphylococcus was one of the leading infections in hospitals and many strains of this bacterium have become antibiotic resistant. Despite strong attempts to get rid of them, staphylococcus bacteria stay present in hospitals, where they can infect people who are most at ...
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Staphylococcus Aureus
''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive for catalase and nitrate reduction and is a facultative anaerobe, meaning that it can grow without oxygen. Although ''S. aureus'' usually acts as a commensal of the human microbiota, it can also become an opportunistic pathogen, being a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. Pathogenic strains often promote infections by producing virulence factors such as potent protein toxins, and the expression of a cell-surface protein that binds and inactivates antibodies. ''S. aureus'' is one of the leading pathogens for deaths associated with antimicrobial resistance and the emergence of antibiotic-resistant strains, such as methicillin-resistant ''S. aur ...
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Flora (microbiology)
In microbiology, collective bacteria and other microorganisms in a host are historically known as flora. Although microflora is commonly used, the term microbiota is becoming more common as microflora is a misnomer. Flora pertains to the Kingdom Plantae. Microbiota includes Archaea, Bacteria, Fungi and Protists. Microbiota with animal-like characteristics can be classified as microfauna. History The terms "Flora" and "Fauna" were first used by Carl Linnaeus from Sweden in the title of his 1745 work ''Flora Suecica and Fauna Suecica''. At that time, biology was focused on macroorganisms. Later, with the advent of microscopy, the new discovered ubiquitous microorganisms were fit in this system. Then, Fauna included moving organisms (animals and protist as "micro-fauna") and Flora the organisms with apparent no movement (plants/fungi; and bacteria as "microflora"). The terms "microfauna" and "microflora" are common in old books, but recently they have been replaced by the more adequa ...
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Body Cavity
A body cavity is any space or compartment, or potential space, in an animal body. Cavities accommodate organs and other structures; cavities as potential spaces contain fluid. The two largest human body cavities are the ventral body cavity, and the dorsal body cavity. In the dorsal body cavity the brain and spinal cord are located. The membranes that surround the central nervous system organs (the brain and the spinal cord, in the cranial and spinal cavities) are the three meninges. The differently lined spaces contain different types of fluid. In the meninges for example the fluid is cerebrospinal fluid; in the abdominal cavity the fluid contained in the peritoneum is a serous fluid. In amniotes and some invertebrates the peritoneum lines their largest body cavity called the coelom. Mammals Mammalian embryos develop two body cavities: the intraembryonic coelom and the extraembryonic coelom (or chorionic cavity). The intraembryonic coelom is lined by somatic and s ...
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Organism
An organism is any life, living thing that functions as an individual. Such a definition raises more problems than it solves, not least because the concept of an individual is also difficult. Many criteria, few of them widely accepted, have been proposed to define what an organism is. Among the most common is that an organism has autonomous reproduction, Cell growth, growth, and metabolism. This would exclude viruses, despite the fact that they evolution, evolve like organisms. Other problematic cases include colonial organisms; a colony of eusocial insects is organised adaptively, and has Germ-Soma Differentiation, germ-soma specialisation, with some insects reproducing, others not, like cells in an animal's body. The body of a siphonophore, a jelly-like marine animal, is composed of organism-like zooids, but the whole structure looks and functions much like an animal such as a jellyfish, the parts collaborating to provide the functions of the colonial organism. The evolutiona ...
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Connective Tissue
Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesoderm, the middle embryonic germ layer. Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord, are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. Blood and lymph are classed as specialized fluid connective tissues that do not contain fiber. All are immersed in the body water. The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leukocytes. The term "connective tissue" (in German, ) was introduced in 1830 by Johannes Peter Müller. The tissue was already recognized as ...
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