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Subserosa
The subserosa or tela subserosa, is a thin layer of tissue in the walls of various organs. It is a layer of connective tissue (usually of the areolar type) between the muscular layer (muscularis externa) and the serosa (serous membrane). The subserosa has clinical importance particularly in cancer staging (for example, in staging stomach cancer or uterine cancer). The subserosa ('' sub-'' + ''serosa'') is to a serous membrane what the submucosa ('' sub-'' + ''mucosa'') is to a mucous membrane A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It .... References External links * - "Female Reproductive System: oviduct; infundibulum" Histology at uio.noDiagram at uniklinik-saarland.de Membrane biology {{Digestive-stub ...
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Gastric Surface
The stomach is a muscular, hollow organ in the upper gastrointestinal tract of humans and many other animals, including several invertebrates. The Ancient Greek name for the stomach is ''gaster'' which is used as ''gastric'' in medical terms related to the stomach. The stomach has a dilated structure and functions as a vital organ in the digestive system. The stomach is involved in the gastric phase of digestion, following the cephalic phase in which the sight and smell of food and the act of chewing are stimuli. In the stomach a chemical breakdown of food takes place by means of secreted digestive enzymes and gastric acid. It also plays a role in regulating gut microbiota, influencing digestion and overall health. The stomach is located between the esophagus and the small intestine. The pyloric sphincter controls the passage of partially digested food (chyme) from the stomach into the duodenum, the first and shortest part of the small intestine, where peristalsis takes over ...
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Submucosa
The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa (mucous membrane) and joins it to the muscular layer, the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle). The submucosa ('' sub-'' + ''mucosa'') is to a mucous membrane what the subserosa ('' sub-'' + ''serosa'') is to a serous membrane. Structure Blood vessels, lymphatic vessels, and nerves (all supplying the mucosa) will run through here. In the intestinal wall, tiny parasympathetic ganglia are scattered around forming the submucous plexus (or "Meissner's plexus") where preganglionic parasympathetic neurons synapse with postganglionic nerve fibers that supply the muscularis mucosae. Histologically, the wall of the alimentary canal shows four distinct layers (from the lumen moving out): mucosa, submuc ...
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Gastric Pits
Gastric pits are indentations in the stomach which denote entrances to 3-5 tubular gastric glands."Secretions from several gastric glands flow into each gastric pit" Principals of Anatomy & Physiology 15th Ed 2017, Gerard Tortora & Bryan Derrickson They are deeper in the pylorus than they are in the other parts of the stomach. The human stomach has several million of these pits which dot the surface of the lining epithelium. Surface mucous cells line the pits themselves but give way to a series of other types of cells which then line the glands themselves. Gastric juice Gastric juice, containing gastric acid, is secreted from gastric glands, which are located in gastric pits. Gastric juice contains hydrochloric acid, pepsinogen and mucus. Hydrochloric acid is secreted by parietal cells, pepsinogen is secreted by gastric chief cell A gastric chief cell, peptic cell, or gastric zymogenic cell is a type of gastric gland cell that releases pepsinogen and gastric lipase. It is the ...
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Gastric Areas
The stomach is a muscular, hollow organ in the upper gastrointestinal tract of humans and many other animals, including several invertebrates. The Ancient Greek name for the stomach is ''gaster'' which is used as ''gastric'' in medical terms related to the stomach. The stomach has a dilated structure and functions as a vital organ in the digestive system. The stomach is involved in the gastric phase of digestion, following the cephalic phase in which the sight and smell of food and the act of chewing are stimuli. In the stomach a chemical breakdown of food takes place by means of secreted digestive enzymes and gastric acid. It also plays a role in regulating gut microbiota, influencing digestion and overall health. The stomach is located between the esophagus and the small intestine. The pyloric sphincter controls the passage of partially digested food (chyme) from the stomach into the duodenum, the first and shortest part of the small intestine, where peristalsis takes ove ...
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Organ (anatomy)
In a multicellular organism, an organ is a collection of Tissue (biology), tissues joined in a structural unit to serve a common function. In the biological organization, hierarchy of life, an organ lies between Tissue (biology), tissue and an organ system. Tissues are formed from same type Cell (biology), cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The Gastrointestinal tract, intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma (tissue), stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerve t ...
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Uterine Cancer
Uterine cancer, also known as womb cancer, includes two types of cancer that develop from the tissues of the uterus. Endometrial cancer forms from the lining of the uterus, and uterine sarcoma forms from the muscles or support tissue of the uterus. Endometrial cancer accounts for approximately 90% of all uterine cancers in the United States. Symptoms of endometrial cancer include changes in vaginal bleeding or pain in the pelvis. Symptoms of uterine sarcoma include unusual vaginal bleeding or a mass in the vagina. Risk factors for endometrial cancer include obesity, metabolic syndrome, type 2 diabetes, taking pills that contain estrogen without progesterone, a history of tamoxifen use, late menopause, and a family history of the condition. Risk factors for uterine sarcoma include prior radiation therapy to the pelvis. Diagnosis of endometrial cancer is typically based on an endometrial biopsy. A diagnosis of uterine sarcoma may be suspected based on symptoms, a pelvic exam, ...
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Stomach Cancer
Stomach cancer, also known as gastric cancer, is a malignant tumor of the stomach. It is a cancer that develops in the Gastric mucosa, lining of the stomach. Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. Lymphomas and mesenchymal tumors may also develop in the stomach. Early symptoms may include heartburn, upper abdominal pain, nausea, and Anorexia (symptom), loss of appetite. Later signs and symptoms may include weight loss, jaundice, yellowing of the skin and whites of the eyes, Hematemesis, vomiting, Dysphagia, difficulty swallowing, and Melena, blood in the stool, among others. The cancer may metastasis, spread from the stomach to other parts of the body, particularly the liver, lungs, bones, peritoneum, lining of the abdomen, and lymph nodes. The bacterium ''Helicobacter pylori'' accounts for more than 60% of cases of stomach cancer. Certain strains of ''H. pylori'' have greater risk ...
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Serous Membrane
The serous membrane (or serosa) is a smooth epithelial membrane of mesothelium lining the contents and inner walls of body cavity, body cavities, which secrete serous fluid to allow lubricated sliding (motion), sliding movements between opposing surfaces. The serous membrane that covers Viscera, internal organs (viscera) is called ''visceral'', while the one that covers the cavity wall is called ''parietal''. For instance the peritoneum, parietal peritoneum is attached to the abdominal wall and the pelvic walls. The peritoneum, visceral peritoneum is wrapped around the visceral organs. For the heart, the layers of the serous membrane are called parietal and visceral pericardium. For the lungs they are called parietal and visceral pleura. The visceral serosa of the uterus is called the perimetrium. The potential space between two opposing serosal surfaces is mostly empty except for the small amount of serous fluid. The Latin anatomical name is Tunica (biology)#Anatomy usages, tu ...
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Muscular Layer
The muscular layer (muscular coat, muscular fibers, muscularis propria, muscularis externa) is a region of muscle in many organs in the vertebrate body, adjacent to the submucosa. It is responsible for gut movement such as peristalsis. The Latin, tunica muscularis, may also be used. Structure It usually has two layers of smooth muscle: * inner and "circular" * outer and "longitudinal" However, there are some exceptions to this pattern. * In the stomach, there are three layers to the muscular layer. Stomach contains an additional oblique muscle layer just interior to circular muscle layer. * In the upper esophagus, part of the externa is ''skeletal muscle'', rather than smooth muscle. * In the vas deferens of the spermatic cord, there are three layers: inner longitudinal, middle circular, and outer longitudinal. * In the ureter, the smooth muscle orientation is opposite that of the GI tract. There is an inner longitudinal and an outer circular layer. The inner layer of the ...
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