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Strychnos Alkaloids
Strychnos alkaloids are Natural product, natural products primarily found in the seeds of the strychnine tree (''Strychnos nux-vomica'') and in the genus ''catharanthus''. Occurrence The seeds of the strychnine tree contain up to 2.5% strychnine and brucine. Representatives The primary representative of this group of alkaloids are strychnine and brucine. Other notable representatives include vomicin and acuammicin. Strychnine Structural Formula V2.svg, Strychnine Brucine Structural Formula V2.svg, Brucine Vomicine Structural Formula V2.svg, Vomicin Akuammicine Structural Formula V2.svg, Akuammicine Stereochemistry The naturally occurring strychnos alkaloids are all chirality (chemistry), chiral and sterically uniform. When this article or the scientific literature names one of these alkaloids without adding another name, it actually states: * acuammicine for (-)-acuammicine, * brucine for (-)-brucine, * strychnine for (-)-strychnine and * vomicin for (+)-vomicin. The br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strychnos Nux-vomica In Kinnarsani WS, AP W IMG 6016
''Strychnos'' is a genus of flowering plants, belonging to the family (biology), family Loganiaceae (sometimes Strychnaceae). The genus includes about 200 accepted species of trees and lianas. The genus is widely distributed around the world's tropics and is noted for the presence of poisonous indole alkaloids in the roots, stems and leaves of various species. Among these alkaloids are the well-known and virulent poisons strychnine and curare. Etymology The name ''strychnos'' was applied by Pliny the Elder in his ''Natural History (Pliny), Natural History'' to ''Solanum nigrum''. The word is derived from the Ancient Greek στρύχνον (''strúkhnon'') – "acrid", "bitter". The meaning of the word ''strychnos'' was not fixed in Ancient Greece, where it could designate a variety of different plants having in common the property of toxicity. Distribution The genus has a pantropical distribution. Taxonomy The genus is divided into 12 sections, though it is conceded that the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Optical Activity
Optical rotation, also known as polarization rotation or circular birefringence, is the rotation of the orientation of the plane of polarization about the optical axis of linearly polarized light as it travels through certain materials. Circular birefringence and circular dichroism are the manifestations of optical activity. Optical activity occurs only in chiral materials, those lacking microscopic mirror symmetry. Unlike other sources of birefringence which alter a beam's state of polarization, optical activity can be observed in fluids. This can include gases or solutions of chiral molecules such as sugars, molecules with helical secondary structure such as some proteins, and also chiral liquid crystals. It can also be observed in chiral solids such as certain crystals with a rotation between adjacent crystal planes (such as quartz) or metamaterials. When looking at the source of light, the rotation of the plane of polarization may be either to the right (dextrorotatory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Total Synthesis
Total synthesis, a specialized area within organic chemistry, focuses on constructing complex organic compounds, especially those found in nature, using laboratory methods. It often involves synthesizing natural products from basic, commercially available starting materials. Total synthesis targets can also be organometallic or inorganic. While total synthesis aims for complete construction from simple starting materials, modifying or partially synthesizing these compounds is known as semisynthesis. Natural product synthesis serves as a critical tool across various scientific fields. In organic chemistry, it tests new synthetic methods, validating and advancing innovative approaches. In medicinal chemistry, natural product synthesis is essential for creating bioactive compounds, driving progress in drug discovery and therapeutic development. Similarly, in chemical biology, it provides research tools for studying biological systems and processes. Additionally, synthesis aids natur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heinrich Wieland
Heinrich Otto Wieland (; 4 June 1877 – 5 August 1957) was a German chemist. He won the 1927 Nobel Prize in Chemistry for his research into the bile acids. Career In 1901 Wieland received his doctorate at the University of Munich while studying under Johannes Thiele. In 1904 he completed his habilitation, then continued to teach at the university and starting in 1907 was a consultant for Boehringer Ingelheim. In 1914 he became associate professor for special topics in organic chemistry, and director of the Organic Division of the State Laboratory in Munich. From 1917 to 1918 Wieland worked in the service of the (KWI) Kaiser Wilhelm Institute for Physical Chemistry and Electrochemistry in Dahlem then led by Fritz Haber as an alternative to regular military service. There he was involved in weapons research for instance finding new synthetic routes for mustard gas. He is also credited with the first synthesis of Adamsite. From 1913 to 1921, he was Professor at the Technical Univ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Robinson (chemist)
Sir Robert Robinson (13 September 1886 – 8 February 1975) was a British organic chemist and Nobel laureate recognised in 1947 for his research on plant dyestuffs (anthocyanins) and alkaloids. In 1947, he also received the Medal of Freedom with Silver Palm. Biography Early life He was born at Rufford House Farm, near Chesterfield, Derbyshire the son of James Bradbury Robinson, a maker of surgical dressings, and his wife, Jane Davenport. Robinson went to school at the Chesterfield Grammar School and the private Fulneck School. He then studied chemistry at the University of Manchester, graduating BSc in 1905. In 1907 he was awarded an 1851 Research Fellowship from the Royal Commission for the Exhibition of 1851 to continue his research at the University of Manchester. He was appointed as the first Professor of Pure and Applied Organic Chemistry in the School of Chemistry at the University of Sydney in 1912. He then took up the Chair in Organic Chemistry at the Universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hermann Leuchs
Friedrich Hermann Leuchs (8 August 1879 – 2 May 1945) was a German chemist. Life Leuchs studied chemistry at the University of Munich from 1898. He transferred to the University of Berlin and received his PhD there in 1902 under Emil Fischer. He steadily advanced in the hierarchy of the university, becoming a lecturer in 1910, assistant professor in 1914, and full professor in 1916. The ministry of education assured him that he would succeed Wilhelm Schlenk as head of the chemistry institute of the University of Berlin, but this never happened. His personality became strongly misanthropic. The Nazi regime, World War II and the destruction of Berlin increased his psychological problems, and shortly before the war ended he committed suicide in his flat in Berlin. This happened most likely on 2 May 1945 (two days after the suicide of Adolf Hitler). He was buried in a mass grave with numerous soldiers and citizens. Work Leuchs's research dealt with the chemistry of amino acids and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heinz Cassebaum
The Kraft Heinz Foods Company, formerly the H. J. Heinz Company and commonly known as Heinz (), is an American food processing company headquartered at One PPG Place in Pittsburgh, Pennsylvania. The company was founded by Henry J. Heinz in 1869. Heinz manufactures food products on six continents, and markets them in more than 200 countries and territories. The company claimed to have 150 number-one or number-two brands worldwide . Heinz ranked first in ketchup in the US with a market share in excess of 50%; the Ore-Ida label held 46% of the frozen potato sector in 2003. Since 1896, the company used its "57 Varieties" slogan; it was inspired by a sign advertising 21 styles of shoes, and Henry Heinz chose the number 57 even though the company then manufactured more than 60 products, because "5" was his lucky number and "7" was his wife's. In February 2013, Heinz agreed to be purchased by Berkshire Hathaway and the Brazilian investment firm 3G Capital for $23billion. On March 25, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ignatius Bean
Ignatius is a male given name and a surname. Notable people with the name include: Given name Religious * Ignatius of Antioch (35–108), saint and martyr, Apostolic Father, early Christian bishop * Ignatius of Constantinople (797–877), Catholic and Eastern Orthodox saint, Patriarch of Constantinople * Ignatios the Deacon (780/790 – after 845), Byzantine bishop and writer * Ignatius of Bulgaria, patriarch in 1272–1277 * Ignatius Brianchaninov (1807–1867), Russian Orthodox saint, bishop and ascetical writer * Ignatius of Jesus (1596–1667), Italian Catholic missionary friar * Ignatius of Laconi (1701–1781), Italian Catholic saint * Ignatius of Loyola (1491–1556), Basque Catholic saint and founder of the Society of Jesus * Ignatius of Moscow (1540–1620), Russian Orthodox Patriarch * Ignatius Moses I Daoud (or Moussa Daoud) (1930–2012), Syrian Catholic Patriarch * Ignatius Zakka I Iwas (born 1933), Syriac Orthodox Patriarch * Ignatius III Atiyah, 17th-century Me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joseph Bienaimé Caventou
Joseph Bienaimé Caventou (; 30 June 1795 – 5 May 1877) was a French pharmacist. He was a professor at the École de Pharmacie (School of Pharmacy) in Paris. He collaborated with Pierre-Joseph Pelletier in a Parisian laboratory located behind an apothecary. He was a pioneer in the use of mild solvents to isolate a number of active ingredients from plants, making a study of alkaloids from vegetables. Among their successes were the isolation of the following compounds: Quinine sulfate later proved to be an important remedy for the disease malaria. Quinine is the active anti-malarial ingredient in the bark of cinchona tree. Neither of the partners chose to patent their discovery of this compound, releasing it for everybody to use. In 1823 they discovered nitrogen in alkaloid compounds. Other compounds they discovered include colchicine and veratrine. The crater Caventou on the Moon The Moon is Earth's only natural satellite. It Orbit of the Moon, orbits around E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pierre Joseph Pelletier
Pierre-Joseph Pelletier ( , , ; 22 March 1788 – 19 July 1842) was a French chemist and pharmacist who did notable research on vegetable alkaloids, and was the co-discoverer with Joseph Bienaimé Caventou of quinine, caffeine, and strychnine Strychnine (, , American English, US chiefly ) is a highly toxicity, toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, .... He was also a collaborator and co-author with Polish chemist Filip Walter. See also * Joseph Bienaimé Caventou * Filip Nariusz Walter References XXMNR Further reading * Scientists from Paris 1788 births 1842 deaths French Roman Catholics 19th-century French chemists French biochemists Members of the French Academy of Sciences {{france-chemist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adalbert Wollrab
Adalbert is a German given name which means "noble bright" or "noble shining", derived from the words ''adal'' (meaning noble) and ''berht'' (shining or bright). Alternative spellings include Adelbart, Adelbert and Adalberto. Derivative names include Albert and Elbert. Because St Adalbert of Prague (†997), early mediaeval missionary who became Czech, Polish and Hungarian patron saint, at his confirmation changed his name from native Vojtěch to Adalbert, this Germanic name has been artificially assigned to Slavonic Vojtěch/Wojciech ("he who is happy in battle") and via the same process have been the names Vojtěch and Adalbert connected with Hungarian name Béla (maybe "inner part") – so, in Central European settings these three names are taken as the equivalents, although they have no linguistic connection to each other. Given name * Adalbert Begas (1836–1888), German painter * Adalbert Baumann (1870–1943), Bavarian teacher * Adalbert Czerny (1863–1941), Austrian ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Racemate
In chemistry, a racemic mixture or racemate () is a mixture that has equal amounts (50:50) of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds are produced industrially as racemates. History The first known racemic mixture was racemic acid, which Louis Pasteur found to be a mixture of the two enantiomeric isomers of tartaric acid. He manually separated the crystals of a mixture, starting from an aqueous solution of the sodium ammonium salt of racemate tartaric acid. Pasteur benefited from the fact that ammonium tartrate salt gives enantiomeric crystals with distinct crystal forms (at 77 °F). Reasoning from the macroscopic scale down to the molecular, he reckoned that the molecules had to have non-superimposable mirror images. A sample with only a single enantiomer is an ''enantiomerically pure'' or ''enantiopure'' compound. Etymology The word ''racemic'' derives from Latin , meaning pertaining to a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
