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Sterubin
Sterubin (7-methoxy-3',4',5-trihydroxyflavanone) is a bitter-masking flavanone extracted from Yerba Santa ('' Eriodictyon californicum'') a plant growing in America. Sterubin is one of the four flavanones identified by Symrise in this plant which elicit taste-modifying properties. The others are homoeriodictyol, its sodium salt, and eriodictyol Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from yerba santa ('' Eriodictyon californicum''), a plant native to North America. Eriodictyol is one of the four flavanones identified in this plant as having taste-modifying prop .... Recent research has demonstrated some neuroprotective properties of Sterubin ''in vitro'', but more research is needed before it can be considered a true drug candidate.Batya Swift Yasgur (Paywalled) Medscape. February 2019. References O-methylated flavanones Bitter-masking compounds Taste modifiers Catechols {{aromatic-stub ...
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Eriodictyon Californicum
''Eriodictyon californicum'' is a species of plant within the family Boraginaceae. It is also known as yerba santa (sacred herb), mountain balm, bear's weed, gum bush, gum plant, and consumptive weed.Patricia Kaminski and Richard Katz.Yerba Santa ''Eriodictyon californicum'' Flower Essence Society. Less common names include Herbe des Montagnes, Herbe à Ourse, Herbe Sacrée, Herbe Sainte, Hierba Santa, Holy Herb, and Tarweed. Description ''Eriodictyon californicum'' is an evergreen aromatic shrub with woody rhizomes, typically found in clonal stands growing to a height of . The dark green, leathery leaves are narrow, oblong to lanceolate, and up to in length. Foliage and twigs are covered with shiny resin and are often dusted with black fungi, ''Heterosporium californicum''. It is similar to its Southern California sibling ''E. crassofolium''. The shrub is known to be an occasional source of nutrition for wildlife and livestock. Their bitterness makes them unpalatable to mos ...
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Homoeriodictyol
Homoeriodictyol is a bitter-masking flavanone extracted from Yerba Santa ('' Eriodictyon californicum'') a plant growing in America. Homoeriodictyol (3`-methoxy-4`,5,7-trihydroxyflavanone) is one of the 4 flavanones identified by Symrise in this plant eliciting taste-modifying property: homoeriodictyol sodium salt, eriodictyol and sterubin. Homoeriodictyol Sodium salt elicited the most potent bitter-masking activity by reducing from 10 to 40% the bitterness of salicin, amarogentin, paracetamol and quinine. However no bitter-masking activity was detected with bitter linoleic acid emulsions. According to Symrise's scientists homoeriodictyol sodium salt seems to be a taste-modifier with large potential in food applications and pharmaceuticals. Structural relatives investigation based on eriodictyol and homoeriodictyol, found 2,4-Dihydroxybenzoic acid vanillylamide to elicits bitter-masking activity. At 0.1g/L, this vanillin derivative, was able to reduce the bitterness of a 0.5g ...
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Eriodictyol
Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from yerba santa ('' Eriodictyon californicum''), a plant native to North America. Eriodictyol is one of the four flavanones identified in this plant as having taste-modifying properties, the other three being homoeriodictyol, its sodium salt, and sterubin. Eriodictyol has garnered scientific attention for its strong antioxidant, anti-inflammatory, and neuroprotective properties. Structurally similar to other flavonoids, such as hesperidin and naringenin, eriodictyol scavenges free radicals and regulates inflammatory responses. Eriodictyol was also found in the twigs of '' Millettia duchesnei'', in '' Eupatorium arnottianum'', and its glycosides ( eriocitrin) in lemons and rose hips (''Rosa canina''). Eriodictyol belongs to the flavanone The flavanones, a type of flavonoids, are various aromatic, colorless ketones derived from flavone that often occur in plants as glycosides. List of flavanones * Blumeatin * ...
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Americas
The Americas, sometimes collectively called America, are a landmass comprising the totality of North America and South America.''Webster's New World College Dictionary'', 2010 by Wiley Publishing, Inc., Cleveland, Ohio. When viewed as a single continent, the Americas or America is the 2nd largest continent by area after Asia, and is the 3rd largest continent by population. The Americas make up most of the land in Earth's Western Hemisphere and comprise the New World. Along with their Lists of islands of the Americas, associated islands, the Americas cover 8% of Earth's total surface area and 28.4% of its land area. The topography is dominated by the American Cordillera, a long chain of mountains that runs the length of the west coast. The flatter eastern side of the Americas is dominated by large river basins, such as the Amazon basin, Amazon, St. Lawrence River–Great Lakes, Mississippi River System, Mississippi, and Río de la Plata Basin, La Plata basins. Since the Americ ...
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Flavanone
The flavanones, a type of flavonoids, are various aromatic, colorless ketones derived from flavone that often occur in plants as glycosides. List of flavanones * Blumeatin * Butin * Dichamanetin * Eriodictyol * Hesperetin * Hesperidin * Homoeriodictyol * Isosakuranetin * Naringenin * Naringin * Pinocembrin * Poncirin * Sakuranetin * Sakuranin * Sterubin * Pinostrobin Metabolism The enzyme chalcone isomerase uses a chalcone-like compound to produce a flavanone. Flavanone 4-reductase is an enzyme that uses (2''S'')-flavan-4-ol The flavan-4-ols (3-deoxyflavonoids) are flavone-derived Alcohol (chemistry), alcohols and a family of flavonoids. Flavan-4-ols are colorless precursor compounds that polymerize to form red phlobaphene pigments. They can be found in the sorghum. Gl ... and NADP+ to produce (2''S'')-flavanone, NADPH, and H+. Synthesis Numerous methods exist for the enantioselective chemical and biochemical synthesis of flavanones and related compounds. Re ...
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Symrise
Symrise AG is a German chemicals company that is a major producer of flavours and fragrances with sales of €4.999 billion i2024 Major competitors include Givaudan, Takasago International Corporation, International Flavors and Fragrances and Döhler. Symrise is a member of the European Flavour Association. In 2021, Symrise was ranked 4th by FoodTalks' Global Top 50 Food Flavours and Fragrances Companies list. History Symrise was founded in 2003 by the merger of Bayer subsidiary Haarmann & Reimer (H&R) and Dragoco, both based in Holzminden, Germany. Haarman & Reimer Haarman & Reimer (H&R) was founded in 1874 by chemists Ferdinand Tiemann and Wilhelm Haarmann after they succeeded in first synthesizing vanillin from coniferin. Holzminden was the site where vanillin was first produced industrially. In 1917, H&R supported Leopold Ružička's unsuccessful three-year project to synthesize irone, a fragrance of violets. In 1953, H&R was acquired by Bayer. Dragoco Dragoco was ...
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Taste Modifiers
The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste. Taste is the perception stimulated when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue. Taste, along with the sense of smell and trigeminal nerve stimulation (registering texture, pain, and temperature), determines flavors of food and other substances. Humans have taste receptors on taste buds and other areas, including the upper surface of the tongue and the epiglottis. The gustatory cortex is responsible for the perception of taste. The tongue is covered with thousands of small bumps called papillae, which are visible to the naked eye. Within each papilla are hundreds of taste buds. The exceptions to this is the filiform papillae that do not contain taste buds. There are between 2000 and 5000Boron, W.F., E.L. Boulpaep. 2003. Medical Physiology. 1st ed. Elsevier Science U ...
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