Spindle Cell (other)
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Spindle Cell (other)
In neurobiology, spindle cell refers to: * Spindle neuron, also known as a von Economo neuron In general medicine, a spindle cell may refer to the spindle-shaped cells that are found in certain types of tumor: * Inflammatory fibroid polyp * Pigmented spindle cell nevus * Spindle cell carcinoma * Spindle cell lipoma * Spindle cell sarcoma See also * Spindle apparatus In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter Cell (biology), cells. It is referred to as the mitotic spindle during mitos ...
(part of a cell) {{disambiguation ...
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Spindle Neuron
Von Economo neurons, also called spindle neurons, are a specific class of mammalian Cerebral cortex, cortical neurons characterized by a large Spindle (textiles), spindle-shaped soma (biology), soma (or body) gradually tapering into a single apical axon (the wikt:ramification , ramification that ''transmits'' signals) in one direction, with only a single dendrite (the ramification that ''receives'' signals) facing opposite. Other cortical neurons tend to have many dendrites, and the Bipolar neuron, bipolar-shaped morphology of von Economo neurons is unique here. Von Economo neurons are found in two very restricted regions in the brains of Hominidae, hominids (humans and other great apes): the anterior cingulate cortex (ACC) and the fronto-insular cortex (FI) (which each make up the salience network). In 2008, they were also found in the dorsolateral prefrontal cortex of humans. Von Economo neurons are also found in the brains of a number of cetaceans, African elephant, African a ...
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Spindle (textiles)
A spindle is a straight spike, usually made from wood, used for spinning, twisting fibers such as wool, flax, hemp, and cotton into yarn. It is often weighted at either the bottom, middle, or top, commonly by a disc or spherical object called a whorl; many spindles, however, are weighted simply by thickening their shape towards the bottom, e.g. Orenburg and French spindles. The spindle may also have a hook, groove, or notch at the top to guide the yarn. Spindles come in many different sizes and weights depending on the thickness of the yarn one desires to spin. History The origin of the first wooden spindle is lost to history because the materials did not survive. Whorl-weighted spindles date back at least to Neolithic times; spindle whorls have been found in archaeological digs around the world. Possible remains of spindle whorls were found in a Natufian village at Nahal Ein Gev II archeological site, Israel, from 12000 years ago. A spindle is also part of traditional spin ...
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Inflammatory Fibroid Polyp
An inflammatory fibroid polyp (IFP) is an uncommon digestive system tumor. J. Vanek initially identified it as a separate pathological entity in 1949 when he reported six case reports of eosinophilic infiltration in gastric submucosal granulomas. It is a single, non-encapsulated polypoid lesion that is typically submucosal. It is characterized by a large number of small blood vessels, oedematous connective tissue, and an inflammatory eosinophilic infiltrate. Inflammatory fibroid polyp has also been referred to as polypoid myo-endothelioma, fibroma with eosinophilic infiltration, inflammatory pseudotumour, myxoma, haemangiopericytoma, eosinophilic granuloma, Vanek's tumour, and gastric eosinophilic submucosal granuloma. When the lesions are symptomatic, they typically measure less than 3 cm in size and are linked to symptoms such as iron deficiency anemia, bleeding, weight loss, and dyspeptic symptoms. Significant complications like obstruction, intussusception, and even hyp ...
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Pigmented Spindle Cell Nevus
A pigmented spindle cell nevus is a skin condition characterized by a dark brown to black macule or papule, usually less than 6 mm. It was characterized in 1975. See also * Partial unilateral lentiginosis * List of cutaneous conditions * Spitz nevus A Spitz nevus is a benign Skin condition#Lesions, skin lesion. A type of melanocytic nevus, it affects the Epidermis (skin), epidermis and dermis.LeBoit, PE, Burg G, Weedon D, Sarasin A. (Eds) World Health Organization Classification of Tumours: ... References External links Melanocytic nevi and neoplasms {{Cutaneous-condition-stub} ...
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Spindle Cell Carcinoma
Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to a ... and that contains long spindle-shaped cells. It is also called sarcomatoid carcinoma. See also * Spindle cell sarcoma * Spindle cell squamous cell carcinoma External links Spindle cell cancerentry in the public domain NCI Dictionary of Cancer Terms Carcinoma {{Oncology-stub ...
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Spindle Cell Lipoma
Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . Signs and symptoms Spindle cell lipoma is most frequently located in the upper back, shoulder, or posterior neck subcutaneous layer. Nonetheless, reports of it occurring in the mediastinum, hypopharynx, larynx, anterior neck, suprasellar region, esophagus, nasal vestibule, tongue, floor of mouth, vallecula, parotid gland, and breast have been made. The tumor is said to have an average diameter of 4 to 5 cm and is growing slowly. Usually, the tumor is painless and solitary. There have been documented rare instances of numerous lesions, including family occurrences. Causes The exact cause of spindle cell lipoma is unknown. Diagnosis The diagnosis of spindle cell lipoma is mainly made in conjunc ...
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Spindle Cell Sarcoma
Spindle cell sarcoma is a type of connective tissue cancer. The tumors generally begin in layers of connective tissue, as found under the skin, between muscles, and surrounding organs, and will generally start as a small, inflamed lump, which grows in size. At first, the lump is, small in size, as the tumor exists in stage 1, and will not necessarily expand beyond its encapsulated form. However, it may develop cancerous traits that can only be detected through microscopic examination or cell-level molecular analysis. As such, at Stage 1, the tumor is usually treated by excision, which includes wide margins of healthy-looking tissue, followed by thorough biopsy, and additional excision, if necessary. The prognosis for a stage 1 tumor excision is usually fairly optimistic, but if the tumor progresses to levels 2 and 3, prognosis worsens, due to tumor cells' likely having spread to other parts of the body, including nearby healthy tissues, or to system-wide locations that include th ...
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