|
Seed-based D Mapping
Seed-based d mapping (formerly Signed differential mapping) or SDM is a statistical technique created by Joaquim Radua for meta-analysis studies assessing differences in brain activity or structure via neuroimaging techniques such as fMRI, VBM, DTI or PET. It may also refer to a specific piece of software created by the SDM Project to carry out such meta-analyses. The seed-based d mapping approach Overview of the method SDM adopted and combined various positive features from previous methods, such as ALE or MKDA, and introduced a series of improvements and novel features. One of the new features, introduced to avoid positive and negative findings in the same voxel as seen in previous methods, was the representation of both positive differences and negative differences in the same map, thus obtaining a signed differential map (SDM). Another relevant feature, introduced in version 2.11, was the use of effect sizes (leading to effect-size SDM or 'ES-SDM'), which allows combinatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical
Statistics (from German language, German: ', "description of a State (polity), state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of statistical survey, surveys and experimental design, experiments. When census data (comprising every member of the target population) cannot be collected, statisticians collect data by developing specific experiment designs and survey sample (statistics), samples. Representative sampling assures that inferences and conclusions can reasonably extend from the sample ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bias Of An Estimator
In statistics, the bias of an estimator (or bias function) is the difference between this estimator's expected value and the true value of the parameter being estimated. An estimator or decision rule with zero bias is called ''unbiased''. In statistics, "bias" is an property of an estimator. Bias is a distinct concept from consistency: consistent estimators converge in probability to the true value of the parameter, but may be biased or unbiased (see bias versus consistency for more). All else being equal, an unbiased estimator is preferable to a biased estimator, although in practice, biased estimators (with generally small bias) are frequently used. When a biased estimator is used, bounds of the bias are calculated. A biased estimator may be used for various reasons: because an unbiased estimator does not exist without further assumptions about a population; because an estimator is difficult to compute (as in unbiased estimation of standard deviation); because a biased esti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monte Carlo Method
Monte Carlo methods, or Monte Carlo experiments, are a broad class of computational algorithms that rely on repeated random sampling to obtain numerical results. The underlying concept is to use randomness to solve problems that might be deterministic in principle. The name comes from the Monte Carlo Casino in Monaco, where the primary developer of the method, mathematician Stanisław Ulam, was inspired by his uncle's gambling habits. Monte Carlo methods are mainly used in three distinct problem classes: optimization, numerical integration, and generating draws from a probability distribution. They can also be used to model phenomena with significant uncertainty in inputs, such as calculating the risk of a nuclear power plant failure. Monte Carlo methods are often implemented using computer simulations, and they can provide approximate solutions to problems that are otherwise intractable or too complex to analyze mathematically. Monte Carlo methods are widely used in va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical Significance
In statistical hypothesis testing, a result has statistical significance when a result at least as "extreme" would be very infrequent if the null hypothesis were true. More precisely, a study's defined significance level, denoted by \alpha, is the probability of the study rejecting the null hypothesis, given that the null hypothesis is true; and the p-value, ''p''-value of a result, ''p'', is the probability of obtaining a result at least as extreme, given that the null hypothesis is true. The result is said to be ''statistically significant'', by the standards of the study, when p \le \alpha. The significance level for a study is chosen before data collection, and is typically set to 5% or much lower—depending on the field of study. In any experiment or Observational study, observation that involves drawing a Sampling (statistics), sample from a Statistical population, population, there is always the possibility that an observed effect would have occurred due to sampling error al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Resampling (statistics)
In statistics, resampling is the creation of new samples based on one observed sample. Resampling methods are: # Permutation tests (also re-randomization tests) for generating counterfactual samples # Bootstrapping # Cross validation # Jackknife Permutation tests Permutation tests rely on resampling the original data assuming the null hypothesis. Based on the resampled data it can be concluded how likely the original data is to occur under the null hypothesis. Bootstrap Bootstrapping is a statistical method for estimating the sampling distribution of an estimator by sampling with replacement from the original sample, most often with the purpose of deriving robust estimates of standard errors and confidence intervals of a population parameter like a mean, median, proportion, odds ratio, correlation coefficient or regression coefficient. It has been called the plug-in principle,Logan, J. David and Wolesensky, Willian R. Mathematical methods in biology. Pure and Ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Confounding
In causal inference, a confounder is a variable that influences both the dependent variable and independent variable, causing a spurious association. Confounding is a causal concept, and as such, cannot be described in terms of correlations or associations.Pearl, J., (2009). Simpson's Paradox, Confounding, and Collapsibility In ''Causality: Models, Reasoning and Inference'' (2nd ed.). New York : Cambridge University Press. The existence of confounders is an important quantitative explanation why correlation does not imply causation. Some notations are explicitly designed to identify the existence, possible existence, or non-existence of confounders in causal relationships between elements of a system. Confounders are threats to internal validity. Example Let's assume that a trucking company owns a fleet of trucks made by two different manufacturers. Trucks made by one manufacturer are called "A Trucks" and trucks made by the other manufacturer are called "B Trucks." ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Linear Model
In statistics, the term linear model refers to any model which assumes linearity in the system. The most common occurrence is in connection with regression models and the term is often taken as synonymous with linear regression model. However, the term is also used in time series analysis with a different meaning. In each case, the designation "linear" is used to identify a subclass of models for which substantial reduction in the complexity of the related statistical theory is possible. Linear regression models For the regression case, the statistical model is as follows. Given a (random) sample (Y_i, X_, \ldots, X_), \, i = 1, \ldots, n the relation between the observations Y_i and the independent variables X_ is formulated as :Y_i = \beta_0 + \beta_1 \phi_1(X_) + \cdots + \beta_p \phi_p(X_) + \varepsilon_i \qquad i = 1, \ldots, n where \phi_1, \ldots, \phi_p may be nonlinear functions. In the above, the quantities \varepsilon_i are random variables representing err ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subgroup Analysis
Subgroup analysis refers to repeating the analysis of a study within subgroups of subjects defined by a subgrouping variable. For example: smoking status defining two subgroups: smokers and non-smokers. See also *Post hoc analysis In a scientific study, post hoc analysis (from Latin ''post hoc'', "after this") consists of statistical analyses that were specified after the data were seen. They are usually used to uncover specific differences between three or more group mean ... References Statistical analysis Design of experiments Medical statistics {{health-informatics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weight Function
A weight function is a mathematical device used when performing a sum, integral, or average to give some elements more "weight" or influence on the result than other elements in the same set. The result of this application of a weight function is a weighted sum or weighted average. Weight functions occur frequently in statistics and analysis, and are closely related to the concept of a measure. Weight functions can be employed in both discrete and continuous settings. They can be used to construct systems of calculus called "weighted calculus" and "meta-calculus".Jane Grossma''Meta-Calculus: Differential and Integral'' , 1981. Discrete weights General definition In the discrete setting, a weight function w \colon A \to \R^+ is a positive function defined on a discrete set A, which is typically finite or countable. The weight function w(a) := 1 corresponds to the ''unweighted'' situation in which all elements have equal weight. One can then apply this weight to various con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mean
A mean is a quantity representing the "center" of a collection of numbers and is intermediate to the extreme values of the set of numbers. There are several kinds of means (or "measures of central tendency") in mathematics, especially in statistics. Each attempts to summarize or typify a given group of data, illustrating the magnitude and sign of the data set. Which of these measures is most illuminating depends on what is being measured, and on context and purpose. The ''arithmetic mean'', also known as "arithmetic average", is the sum of the values divided by the number of values. The arithmetic mean of a set of numbers ''x''1, ''x''2, ..., x''n'' is typically denoted using an overhead bar, \bar. If the numbers are from observing a sample of a larger group, the arithmetic mean is termed the '' sample mean'' (\bar) to distinguish it from the group mean (or expected value) of the underlying distribution, denoted \mu or \mu_x. Outside probability and statistics, a wide rang ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coregistration
Image registration is the process of transforming different sets of data into one coordinate system. Data may be multiple photographs, data from different sensors, times, depths, or viewpoints. It is used in computer vision, medical imaging, military automatic target recognition, and compiling and analyzing images and data from satellites. Registration is necessary in order to be able to compare or integrate the data obtained from these different measurements. Algorithm classification Intensity-based vs feature-based Image registration or image alignment algorithms can be classified into intensity-based and feature-based.A. Ardeshir Goshtasby2-D and 3-D Image Registration for Medical, Remote Sensing, and Industrial Applications Wiley Press, 2005. One of the images is referred to as the ''target'', ''fixed'' or ''sensed'' image and the others are referred to as the ''moving'' or ''source'' images. Image registration involves spatially transforming the source/moving image(s) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full Width At Half Maximum
In a distribution, full width at half maximum (FWHM) is the difference between the two values of the independent variable at which the dependent variable is equal to half of its maximum value. In other words, it is the width of a spectrum curve measured between those points on the ''y''-axis which are half the maximum amplitude. Half width at half maximum (HWHM) is half of the FWHM if the function is symmetric. The term full duration at half maximum (FDHM) is preferred when the independent variable is time. FWHM is applied to such phenomena as the duration of pulse waveforms and the spectral width of sources used for optical communications and the resolution of spectrometers. The convention of "width" meaning "half maximum" is also widely used in signal processing to define bandwidth as "width of frequency range where less than half the signal's power is attenuated", i.e., the power is at least half the maximum. In signal processing terms, this is at most −3 dB of att ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
