Salt Water Aspiration Syndrome
Salt water aspiration syndrome or saltwater aspiration syndrome is a medical condition caused by the inhalation or aspiration (entry of materials into lungs from mouth) of small amounts of salt water during an underwater dive, leading to lung irritation and inflammation. Unlike drowning or near-drowning, it does not involve ingestion of large volumes of water. It often results from faulty diving equipment or improper breathing techniques, allowing fine water droplets to reach the lower respiratory tract. The condition begins with a cough, followed by shortness of breath, chest discomfort or pain, shivering, fever and other systemic symptoms. It can resemble a viral infection but improves within hours, especially with supplemental oxygen. While most cases resolve on their own, severe instances may require critical care. Diagnosis is based on clinical history and symptom progression. Salt water aspiration syndrome was first described in 1970. Cause and mechanism Salt water a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pulmonary Aspiration
Pulmonary aspiration is the entry of solid or liquid material such as pharyngeal secretions, food, drink, or stomach contents from the oropharynx or gastrointestinal tract, into the trachea and lungs. When pulmonary aspiration occurs during eating and drinking, the aspirated material is often colloquially referred to as "going down the wrong pipe". Consequences of pulmonary aspiration include no injury at all, chemical pneumonitis, pneumonia, or even death from asphyxiation. These consequences depend on the volume, chemical composition, particle size, and presence of infectious agents in the aspirated material, and on the underlying health status of the person. In healthy people, aspiration of small quantities of material is common and rarely results in disease or injury. People with significant underlying disease or injury are at greater risk for developing respiratory complications following pulmonary aspiration, especially hospitalized patients, because of certain factors ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Buddy Breathing
Buddy breathing is a rescue technique used in scuba diving "out-of-gas" emergencies, when two divers share one demand valve, alternately breathing from it. Techniques have been developed for buddy breathing from both twin-hose and single hose regulators, but to a large extent it has been superseded by safer and more reliable techniques using additional equipment, such as the use of a bailout cylinder or breathing through a secondary demand valve on the rescuer's regulator. Running out of breathing gas most commonly happens as a result of poor gas management. It can also happen due to unforeseen exertion or breathing equipment failure. Equipment failure resulting in the loss of all gas could be caused by failure of a pressure retaining component such as an O-ring or hose in the regulator or, in cold conditions, a freezing of water in the regulator resulting in a free flow from the demand valve. Technique Buddy breathing is usually initialised by the diver with the "out of air" ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Marine Microorganisms
Marine microorganisms are defined by their habitat as microorganisms living in a marine habitat, marine environment, that is, in the saline water, saltwater of a sea or ocean or the brackish water of a coastal estuary. A microorganism (or microbe) is any microscopic scale, microscopic life, living organism or virus, which is invisibly small to the naked eye, unaided human eye without magnification. Microorganisms are very diverse. They can be unicellular organism, single-celled or multicellular organism, multicellular and include bacteria, archaea, viruses, and most protozoa, as well as some fungi, algae, and animals, such as rotifers and copepods. Many macroscopic scale, macroscopic animals and plants have microscopic juvenile (organism), juvenile stages. Some microbiologists also classify viruses as microorganisms, but others consider these as non-living. Marine microorganisms have been variously estimated to make up about 70%, or about 90%, Modified text was copied from th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Spandidos Publications
Demetrios A. Spandidos is a Greek virologist and cancer researcher. He is an emeritus professor at the University of Crete where he was professor of virology from 1989 till 2015. He is also the founder of Spandidos Publications and the editor-in-chief of all eight of its journals. Education Spandidos received his bachelor's degree from the University of Thessaloniki in 1971, his PhD from McGill University in 1976, and a DSc from the University of Glasgow in 1989. Career From 1976 to 1978, Spandidos worked as a postdoctoral fellow at the University of Toronto, working in the laboratory of Louis Siminovitch. In 1978, Spandidos gave a presentation to a Dana Farber Cancer Institute seminar. In this presentation, Spandidos claimed to have proven that oncogenes were the root cause of all cancers. Robert Weinberg (biologist), Robert Weinberg, a professor at the Massachusetts Institute of Technology, was in the audience when Spandidos gave this talk, and later recalled that he had ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Apoptosis
Apoptosis (from ) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. Biochemistry, Biochemical events lead to characteristic cell changes (Morphology (biology), morphology) and death. These changes include Bleb (cell biology), blebbing, Plasmolysis, cell shrinkage, Karyorrhexis, nuclear fragmentation, Pyknosis, chromatin condensation, Apoptotic DNA fragmentation, DNA fragmentation, and mRNA decay. The average adult human loses 50 to 70 1,000,000,000, billion cells each day due to apoptosis. For the average human child between 8 and 14 years old, each day the approximate loss is 20 to 30 billion cells. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Autophagy
Autophagy (or autophagocytosis; from the Greek language, Greek , , meaning "self-devouring" and , , meaning "hollow") is the natural, conserved degradation of the cell that removes unnecessary or dysfunctional components through a lysosome-dependent regulated mechanism. It allows the orderly degradation and recycling of cellular components. Although initially characterized as a primordial degradation pathway induced to protect against starvation, it has become increasingly clear that autophagy also plays a major role in the homeostasis of non-starved cells. Defects in autophagy have been linked to various human diseases, including neurodegeneration and cancer, and interest in modulating autophagy as a potential treatment for these diseases has grown rapidly. Four forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. In macroautophagy (the most thoroughly researched form of autophagy), cytoplasmic components ( ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pulmonary Surfactant
Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by Type II cells, type II alveolar cells. The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions. By adsorption, adsorbing to the air-water Interface (chemistry), interface of pulmonary alveolus, alveoli, with hydrophilic head groups in the water and the hydrophobic tails facing towards the air, the main lipid component of the surfactant, dipalmitoylphosphatidylcholine (DPPC), reduces surface tension. As a medication, Pulmonary surfactant (medication), pulmonary surfactant is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. Function * To increase pulmonary compliance. * To prevent atelectasis (collapse of the alveoli or atriums) at the end of expiration. * To facilitate recruitment of collapsed airways. Alveoli can be compared to gas in water, as the alveoli are wet and surround a central a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oxidative Stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from oxidative metabolism causes base damage, as well as strand breaks in DNA. Base damage is mostly indirect and caused by the reactive oxygen species generated, e.g., (superoxide radical), OH ( hydroxyl radical) and (hydrogen peroxide). Further, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling. In humans, oxidative stress is thought to be involved in the development of attention deficit hyperactivity disorder, cancer, Parkin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bronchioles
The bronchioles ( ) are the smaller branches of the bronchial airways in the lower respiratory tract. They include the terminal bronchioles, and finally the respiratory bronchioles that mark the start of the respiratory zone delivering air to the gas exchanging units of the alveoli. The bronchioles no longer contain the cartilage that is found in the bronchi, or glands in their submucosa. Structure The pulmonary lobule is the portion of the lung ventilated by one bronchiole. Bronchioles are approximately 1 mm or less in diameter and their walls consist of ciliated cuboidal epithelium and a layer of smooth muscle. Bronchioles divide into even smaller bronchioles, called ''terminal'', which are 0.5 mm or less in diameter. Terminal bronchioles in turn divide into smaller respiratory bronchioles which divide into alveolar ducts. Terminal bronchioles mark the end of the conducting division of air flow in the respiratory system while respiratory bronchioles are the be ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lung Alveoli
A pulmonary alveolus (; ), also called an air sac or air space, is one of millions of hollow, distensible cup-shaped cavities in the lungs where pulmonary gas exchange takes place. Oxygen is exchanged for carbon dioxide at the blood–air barrier between the alveolar air and the pulmonary capillary. Alveoli make up the functional tissue of the mammalian lungs known as the lung parenchyma, which takes up 90 percent of the total lung volume. Alveoli are first located in the respiratory bronchioles that mark the beginning of the respiratory zone. They are located sparsely in these bronchioles, line the walls of the alveolar ducts, and are more numerous in the blind-ended alveolar sacs. The acini are the basic units of respiration, with gas exchange taking place in all the alveoli present. The alveolar membrane is the gas exchange surface, surrounded by a network of capillaries. Oxygen is diffused across the membrane into the capillaries and carbon dioxide is released from the c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Edema
Edema (American English), also spelled oedema (British English), and also known as fluid retention, swelling, dropsy and hydropsy, is the build-up of fluid in the body's tissue (biology), tissue. Most commonly, the legs or arms are affected. Symptoms may include skin that feels tight, the area feeling heavy, and joint stiffness. Other symptoms depend on the underlying cause. Causes may include Chronic venous insufficiency, venous insufficiency, heart failure, kidney problems, hypoalbuminemia, low protein levels, liver problems, deep vein thrombosis, infections, kwashiorkor, angioedema, certain medications, and lymphedema. It may also occur in immobile patients (stroke, spinal cord injury, aging), or with temporary immobility such as prolonged sitting or standing, and during menstruation or pregnancy. The condition is more concerning if it starts suddenly, or pain or shortness of breath is present. Treatment depends on the underlying cause. If the underlying mechanism involve ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |