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Rs5569
In genetics, rs5569 (A1287G or G1287A) is a genetic variant. It is a single nucleotide polymorphism (SNP) in the '' SLC6A2'' gene in exon 9. This gene codes the norepinephrine transporter. The SNP is a silent substitution and the nucleotides of both variants code a threonine amino acid. Several research studies have examined the effect of the variant in relation to alcohol dependence, attention deficit hyperactivity disorder, diabetes, major depressive disorder, panic disorder, Tourette syndrome and personality traits. None of the studies have found an association. References Further reading * {{Cite journal , author = E. G. Jonsson, M. M. Nothen, J. P. Gustavsson, H. Neidt, R. Bunzel, P. Propping & G. C. Sedvall , title = Polymorphisms in the dopamine, serotonin, and norepinephrine transporter genes and their relationships to monoamine metabolite concentrations in CSF of healthy volunteers , journal = Psychiatry Research ''Psychiatry Research'' is a peer-reviewed m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuropsychobiology
''Neuropsychobiology'' is a peer-reviewed scientific journal that focuses on neuroscience, psychopharmacology, and biological psychiatry Biological psychiatry or biopsychiatry is an approach to psychiatry that aims to understand mental disorder in terms of the biological function of the nervous system. It is interdisciplinary in its approach and draws on sciences such as neuroscie .... It was established in 1975 and is published by Karger Publishers. Karger academic journals English-language journals Neuroscience journals Publications established in 1975 8 times per year journals {{neuroscience-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychiatric Genetics (journal)
''Psychiatric Genetics'' is a bimonthly medical journal published by Lippincott Williams & Wilkins within the field of psychiatric genetics. It is abstracted and indexed in MEDLINE/PubMed, BIOSIS Previews and the Science Citation Index Expanded. According to the ''Journal Citation Reports'', the journal has a 2017 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 1.586. See also * List of psychiatry journals References External links * Behavioural genetics journals Psychiatry journals Medical genetics journals Lippincott Williams & Wilkins academic journals Bimonthly journals English-language journals Publications established in 1990 {{genetics-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tourette Syndrome
Tourette syndrome or Tourette's syndrome (abbreviated as TS or Tourette's) is a common neurodevelopmental disorder that begins in childhood or adolescence. It is characterized by multiple movement (motor) tics and at least one vocal (phonic) tic. Common tics are blinking, coughing, throat clearing, sniffing, and facial movements. These are typically preceded by an unwanted urge or sensation in the affected muscles known as a premonitory urge, can sometimes be suppressed temporarily, and characteristically change in location, strength, and frequency. Tourette's is at the more severe end of a spectrum of tic disorders. The tics often go unnoticed by casual observers. Tourette's was once regarded as a rare and bizarre syndrome and has popularly been associated with coprolalia (the utterance of obscene words or socially inappropriate and derogatory remarks). It is no longer considered rare; about 1% of school-age children and adolescents are estimated to have Tourette's, and c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience Letters
''Neuroscience Letters'' is a biweekly rapid-publication scientific journal for short articles covering all aspects of neuroscience. According to the ''Journal Citation Reports'', ''Neuroscience Letters'' has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 3.046. References Neuroscience journals Elsevier academic journals Publications established in 1975 English-language journals Biweekly journals {{neuroscience-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Panic Disorder
Panic disorder is a mental and behavioral disorder, specifically an anxiety disorder characterized by reoccurring unexpected panic attacks. Panic attacks are sudden periods of intense fear that may include palpitations, sweating, shaking, shortness of breath, numbness, or a feeling that something terrible is going to happen. The maximum degree of symptoms occurs within minutes. There may be ongoing worries about having further attacks and avoidance of places where attacks have occurred in the past. The cause of panic disorder is unknown. Panic disorder often runs in families. Risk factors include smoking, psychological stress, and a history of child abuse. Diagnosis involves ruling out other potential causes of anxiety including other mental disorders, medical conditions such as heart disease or hyperthyroidism, and drug use. Screening for the condition may be done using a questionnaire. Panic disorder is usually treated with counselling and medications. The typ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological & Pharmaceutical Bulletin
''Biological and Pharmaceutical Bulletin'' is a monthly peer reviewed medical journal published by the Pharmaceutical Society of Japan. The journal was established in 1993 as the successor to '' The Journal of Pharmacobio-Dynamics'' (established in 1978). In 2012, the society re-organized its journals, and most material published in the '' Journal of Health Science'' now started to be published in ''Biological and Pharmaceutical Bulletin'' and with some being published in its sister publication ''Chemical and Pharmaceutical Bulletin''. The editor in chief is Naoto Oku (University of Shizuoka). Abstracting and indexing ''Biological and Pharmaceutical Bulletin'' is abstracted and indexed in the following databases: *Biosis *Chemical Abstracts Core *Chimica *MEDLINE *Veterinary Science Database *Science Citation Index Expanded *Scopus Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuropsychopharmacology (journal)
''Neuropsychopharmacology'' is a monthly peer-reviewed scientific journal published by Springer Nature. It was established in 1987 and is an official publication of the American College of Neuropsychopharmacology. The journal covers all aspects of neuropsychopharmacology, including clinical and basic science research into the brain and behavior, the properties of agents acting within the central nervous system, and drug targeting and development. Editors-in-chief Over the years, there have been ten editors-in-chief ("principal editors"), including J. Christian Gillin (1987-1993), Ronald D. Ciaranello (1994), Herbert Y. Meltzer (1994-1998), Hans C. Fibiger (1995-1998), Robert H. Lenox (1999-2001), Charles B. Nemeroff (2002-2006), and James H. Meador-Woodruff (2007-2012) and William A. Carlezon, Jr. (2013-2022). Since 2023, Tony P. George (University of Toronto) and Lisa M. Monteggia (Vanderbilt University) have been co-editors. Abstracting and indexing The journal is abs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Major Depressive Disorder
Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, the term was adopted by the American Psychiatric Association for this symptom cluster under mood disorders in the 1980 version of the '' Diagnostic and Statistical Manual of Mental Disorders'' (DSM-III), and has become widely used since. The diagnosis of major depressive disorder is based on the person's reported experiences, behavior reported by relatives or friends, and a mental status examination. There is no laboratory test for the disorder, but testing may be done to rule out physical conditions that can cause similar symptoms. The most common time of onset is in a person's 20s, with females affected about twice as often as males. The course of the disorder varies widely, from one e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kidney And Blood Pressure Research
Karger Publishers (also: Karger Medical and Scientific Publishers, S. Karger AG) is an academic publisher of scientific and medical journals and books. The current CEO is Daniel Ebneter. History The company was founded in 1890 in Berlin by Samuel Karger, who remained at the helm of the company until his death in 1935. His son, Heinz Karger led the company until his death in 1959, and Heinz's son (and Samuel's grandson) Thomas Karger took over the leadership of the company; he was followed as the company leader by his eldest son, Steven Karger, and, most recently, by his youngest daughter, Gabriella Karger, who leads the publishing house now. Its first medical journal, '' Dermatologische Zeitschrift'' (later: ''Dermatologica'', now: ''Dermatology'') was established in 1893. The company published works from well-known scientists such as Sigmund Freud. Because of political pressure from the Nazi regime, the company was relocated to Basel, Switzerland, in 1937 and lost all German aut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level (hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Attention Deficit Hyperactivity Disorder
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by excessive amounts of inattention, hyperactivity, and impulsivity that are pervasive, impairing in multiple contexts, and otherwise age-inappropriate. ADHD symptoms arise from executive dysfunction, and emotional dysregulation is often considered a core symptom. In children, problems paying attention may result in poor school performance. ADHD is associated with other neurodevelopmental and mental disorders as well as some non-psychiatric disorders, which can cause additional impairment, especially in modern society. Although people with ADHD struggle to focus on tasks they are not particularly interested in completing, they are often able to maintain an unusually prolonged and intense level of attention for tasks they do find interesting or rewarding; this is known as hyperfocus. The precise causes of ADHD are unknown in the majority of cases. Genetic factors play an im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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