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Renal Column
The renal columns, Bertin columns, or columns of Bertin, a.k.a. columns of Bertini are extensions of the renal cortex in between the renal pyramids. They allow the cortex to be better anchored. (Cortical extensions into the medullary space.) Each column consists of lines of blood vessels and urinary tubes and a fibrous material. A hypertrophied renal column (or ''renal pseudotumor'') may be differentiated from an actual renal tumor with the help of a DMSA scan. The scan will show the area as one with normal activity if it is a pseudotumor or will show decreased uptake if it is a cystic or solid renal mass. See also * Renal pyramids * Renal papilla * Renal medulla The renal medulla (Latin: ''medulla renis'' 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which ... Additional images File:Slide12iii.JPG, Renal column File:Slide1 ...
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Renal Pyramid
The renal medulla (Latin: ''medulla renis'' 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries. The interlobar arteries each in turn branch into arcuate arteries, which in turn branch to form interlobular arteries, and these finally reach the glomerulus (kidney), glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum (blood), serum portion of the blood out of the vessel and into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the loop of Henle, through the distal tubule and finally leaves the kidney by means of the collecting duct, leading to the renal pelvis, the dilated portion of the ureter. The renal med ...
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Nephron
The nephron is the minute or microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule. The renal tubule extends from the capsule. The capsule and tubule are connected and are composed of epithelial cells with a lumen. A healthy adult has 1 to 1.5 million nephrons in each kidney. Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the podocyte foot processes of the lining of the capsule. The tubule has adjacent peritubular capillaries that run between the descending and ascending portions of the tubule. As the fluid from the capsule flows down into the tubule, it is processed by the epithelial cells lining the tubule: water is reabsorbed and substances are exchanged (some are added, others are removed); first wit ...
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Renal Pyramids
The renal medulla (Latin: ''medulla renis'' 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries. The interlobar arteries each in turn branch into arcuate arteries, which in turn branch to form interlobular arteries, and these finally reach the glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum portion of the blood out of the vessel and into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the loop of Henle, through the distal tubule and finally leaves the kidney by means of the collecting duct, leading to the renal pelvis, the dilated portion of the ureter. The renal medulla contains the structures of t ...
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DMSA Scan
A DMSA scan is a radionuclide scan that uses dimercaptosuccinic acid (DMSA) in assessing renal morphology, structure and function. Radioactive technetium-99m is combined with DMSA and injected into a patient, followed by imaging with a gamma camera after 2-3 hours. A DMSA scan is usually static imaging, while other radiotracers like DTPA and MAG3 are usually used for dynamic imaging to assess renal excretion. The major clinical indications for this investigation are # Detection and/or evaluation of a renal scar, especially in patients having vesicoureteric reflux (VUR) # Small or absent kidney (renal agenesis), # Ectopic kidneys (sometimes cannot be visualized by ultrasonography of abdomen due to intestinal gas) # Evaluation of an occult duplex system, # Characterization of certain renal masses, # Evaluation of systemic hypertension especially young hypertensive and in cases of suspected vasculitis. # It is sometimes used as a test for the diagnosis of acute pyelonephritis ...
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Renal Tumor
Kidney tumours are tumours, or growths, on or in the kidney. These growths can be benign or malignant (kidney cancer). Presentation Kidney tumours may be discovered on medical imaging incidentally (i.e. an incidentaloma), or may be present in patients as an abdominal mass or kidney cyst, hematuria Hematuria or haematuria is defined as the presence of blood or red blood cells in the urine. "Gross hematuria" occurs when urine appears red, brown, or tea-colored due to the presence of blood. Hematuria may also be subtle and only detectable with ..., abdominal pain, or manifest first in a paraneoplastic syndrome that seems unrelated to the kidney. Other markers or complications that may arise from kidney tumours can appear to be more subtle, including; low hemoglobin, fatigue, nausea, constipation, and/or hyperglycemia. Diagnosis A CT scan is the first choice modality for workup of solid masses in the kidneys. Nevertheless, hemorrhagic cysts can resemble renal cell carcinomas on CT, ...
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Renal Pyramid
The renal medulla (Latin: ''medulla renis'' 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries. The interlobar arteries each in turn branch into arcuate arteries, which in turn branch to form interlobular arteries, and these finally reach the glomerulus (kidney), glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum (blood), serum portion of the blood out of the vessel and into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the loop of Henle, through the distal tubule and finally leaves the kidney by means of the collecting duct, leading to the renal pelvis, the dilated portion of the ureter. The renal med ...
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Renal Cortex
The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. In the adult, it forms a continuous smooth outer zone with a number of projections ( cortical columns) that extend down between the pyramids. It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs. Erythropoietin is produced in the renal cortex. Additional images File:Njuren.gif, Kidney File:Kidney-Cortex.JPG, Microscopic cross section of the renal cortex File:Kidney_cd10_ihc.jpg, CD10 immunohistochemical staining of normal kidney In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organ (anatomy), organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the le ...
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Urinary System
The human urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, urinary bladder, bladder, and the urethra. The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressure, control levels of Electrolyte, electrolytes and Metabolite, metabolites, and regulate Acid–base homeostasis, blood pH. The urinary tract is the body's drainage system for the eventual removal of urine. The kidneys have an extensive blood supply via the Renal artery, renal arteries which leave the kidneys via the renal vein. Each kidney consists of functional units called nephrons. Following filtration of blood and further processing, waste (in the form of urine) exits the kidney via the ureters, tubes made of smooth muscle fibres that propel urine towards the urinary bladder, where it is stored and subsequently expelled through the urethra during urination. The female and male urinary system are very similar, differin ...
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Renal Papilla
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid-base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and func ...
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Major Calyx
The renal calyces ( calyx) are conduits in the kidney through which urine passes. The minor calyces form a cup-shaped drain around the apex of the renal pyramids. Urine formed in the kidney passes through a renal papilla at the apex into the minor calyx; four or five minor calyces converge to form a major calyx through which urine passes into the renal pelvis (which in turn drains urine out of the kidney through the ureter). Function Peristalsis of the smooth muscle originating in pace-maker cells originating in the walls of the calyces propels urine through the renal pelvis and ureters to the bladder. The initiation is caused by the increase in volume that stretches the walls of the calyces. This causes them to fire impulses which stimulate rhythmical contraction and relaxation, called peristalsis. Parasympathetic innervation enhances the peristalsis while sympathetic innervation inhibits it. Clinical significance A "staghorn calculus" is a kidney stone that may extend into ...
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Renal Sinus
The renal sinus is a cavity within the kidney which is occupied by the renal pelvis, renal calyces, blood vessels, nerves and fat. The renal hilum extends into a large cavity within the kidney occupied by the renal vessels, minor renal calyces, major renal calyces, renal pelvis and some adipose tissue Adipose tissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes. It also contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, Blood vessel, vascular endothel .... Additional images File:Slide3iii.JPG, Renal sinus File:Slide22iii.JPG, Renal sinus References Kidney anatomy {{genitourinary-stub ...
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