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Psychological Resilience
Psychological resilience, or mental resilience, is the ability to cope mentally and emotionally with a crisis, or to return to pre-crisis status quickly. The term was popularized in the 1970s and 1980s by psychologist Emmy Werner as she conducted a forty-year-long study of a cohort of Hawaiian children who came from low socioeconomic status backgrounds. Numerous factors influence a person's level of resilience. Internal factors include personal characteristics such as self-esteem, self-regulation, and a positive outlook on life. External factors include social support systems, including relationships with family, friends, and community, as well as access to resources and opportunities. People can leverage psychological interventions and other strategies to enhance their resilience and better cope with adversity. These include cognitive-behavioral techniques, mindfulness practices, building psychosocial factors, fostering positive emotions, and promoting self-compassion. ...
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Coping (psychology)
Coping refers to conscious or unconscious strategies used to reduce and manage unpleasant emotions. Coping strategies can be cognitions or behaviors and can be individual or social. To cope is to deal with struggles and difficulties in life. It is a way for people to maintain their mental and emotional well-being. Everybody has ways of handling difficult events that occur in life, and that is what it means to cope. Coping can be healthy and productive, or unhealthy and destructive. It is recommended that an individual cope in ways that will be beneficial and healthy. "Managing your stress well can help you feel better physically and psychologically and it can impact your ability to perform your best." Theories of coping Hundreds of coping strategies have been proposed in an attempt to understand how people cope. Classification of these strategies into a broader architecture has not been agreed upon. Researchers try to group coping responses rationally, empirically by factor a ...
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Self-concept
In the psychology of self, one's self-concept (also called self-construction, self-identity, self-perspective or self-structure) is a collection of beliefs about oneself. Generally, self-concept embodies the answer to the question ''"Who am I?".'' The self-concept is distinguishable from self-awareness, which is the extent to which self-knowledge (psychology), self-knowledge is defined, consistent, and currently applicable to one's Attitude (psychology), attitudes and dispositions. Self-concept also differs from self-esteem: self-concept is a cognitive or descriptive component of one's self (e.g. "I am a fast runner"), while self-esteem is evaluative and opinionated (e.g. "I feel good about being a fast runner"). Self-concept is made up of one's self-schemas, and interacts with self-esteem, self-knowledge, and the social self to form the self as a whole. It includes the past, present, and future selves, where future selves (or possible selves) represent individuals' ideas of w ...
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Schizophrenic
Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, flat or inappropriate affect. Symptoms Prodrome, develop gradually and typically begin during young adulthood and rarely resolve. There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person. For a diagnosis of schizophrenia, the described symptoms need to have been present for at least six months (according to the DSM-5) or one month (according to the ICD-11). Many people with schizophrenia have other mental disorders, especially mood disorder, mood, anxiety disorder, anxiety, and substance use disorders, substance use disorders, as well as obsessive–compulsive disorder (OCD). About 0.3% to 0.7% of peo ...
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Marriage
Marriage, also called matrimony or wedlock, is a culturally and often legally recognised union between people called spouses. It establishes rights and obligations between them, as well as between them and their children (if any), and between them and their Affinity (law), in-laws. It is nearly a cultural universal, but the definition of marriage varies between cultures and religions, and over time. Typically, it is an institution in which interpersonal relationships, usually sexual, are acknowledged or sanctioned. In some cultures, marriage is recommended or considered to be Premarital sex, compulsory before pursuing sexual activity. A marriage ceremony is called a wedding, while a private marriage is sometimes called an elopement. Around the world, there has been a general trend towards ensuring Women's rights, equal rights for women and ending discrimination and harassment against couples who are Interethnic marriage, interethnic, Interracial marriage, interracial, In ...
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Hawaii
Hawaii ( ; ) is an island U.S. state, state of the United States, in the Pacific Ocean about southwest of the U.S. mainland. One of the two Non-contiguous United States, non-contiguous U.S. states (along with Alaska), it is the only state not on the North American mainland, the only state that is an archipelago, and the only state in the tropics. Hawaii consists of 137 volcanic islands that comprise almost the entire Hawaiian Islands, Hawaiian archipelago (the exception, which is outside the state, is Midway Atoll). Spanning , the state is Physical geography, physiographically and Ethnology, ethnologically part of the Polynesian subregion of Oceania. Hawaii's ocean coastline is consequently the List of U.S. states and territories by coastline, fourth-longest in the U.S., at about . The eight main islands, from northwest to southeast, are Niihau, Niihau, Kauai, Kauai, Oahu, Oahu, Molokai, Molokai, Lanai, Lānai, Kahoʻolawe, Kahoolawe, Maui, and Hawaii (island), Hawaii, a ...
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Kauai
Kauai (), anglicized as Kauai ( or ), is one of the main Hawaiian Islands. It has an area of 562.3 square miles (1,456.4 km2), making it the fourth-largest of the islands and the 21st-largest island in the United States. Kauai lies 73 miles (117 km) northwest of Oahu, across the Kauai Channel. The island's 2020 population was 73,298. Styling itself the "Garden Isle", Kauai is the site of Waimea Canyon State Park and Nā Pali Coast State Park. It forms the bulk of Kauai County, which includes Niihau as well as the small nearby islands of Kaula and Lehua. Etymology and language Hawaiian narrative derives the name's origin from the legend of Hawaiiloa, the Polynesian navigator credited with discovering the Hawaiian Islands. The story relates that he named the island after a favorite son; a possible translation of Kauai is "place around the neck", describing how a father would carry his child. Another possible translation is "food season". Kauai was known for its ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent diseases. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying Risk factor (epidemiology), risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission (medicine), transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic ...
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Oxytocin
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. Present in animals since early stages of evolution, in humans it plays roles in behavior that include Human bonding, social bonding, love, reproduction, childbirth, and the Postpartum period, period after childbirth. Oxytocin is released into the bloodstream as a hormone in response to Human sexual activity, sexual activity and during childbirth. It is also available in Oxytocin (medication), pharmaceutical form. In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. In its natural form, it also plays a role in maternal bonding and lactation, milk production. Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further oxytocin. For example, when oxytocin is released during a contraction of the uterus at the start of c ...
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Blood–brain Barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane, semipermeable border of endothelium, endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. The blood–brain barrier is formed by endothelial cells of the Capillary, capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system allows the passage of some small molecules by passive transport, passive diffusion, as well as the selective and active transport of various nutrients, ions, organic anions, and macromolecules such as glucose and amino acids that are crucial to neural function. The blood–brain barrier restricts the passage of pathogens, the diffusion of solutes in the blood, and Molecular mass, large or Hydrophile, hydrophilic molecules into the cerebrospinal fluid, while a ...
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Glial Cell Line-derived Neurotrophic Factor
Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the ''GDNF'' gene. GDNF is a small protein that potently promotes the survival of many types of neurons. It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes, i.e. it is received by RET proto-oncogene (RET) and by forming gradient with SCF it divides the spermatogonia into two cells. As the result there is retention of spermatogonia and formation of spermatocyte. History GDNF was discovered in 1991 and was the first identified member of the GDNF family of ligands (GFL). Structure GDNF has a structure that is similar to TGF beta 2. GDNF has two finger-like structures that interact with the GFRα1 receptor. N-linked glycosylation, which occurs during the secretion of pro-GDNF, takes place at the tip of one of the finger-like structures. The C-terminal of mature GDNF plays an important r ...
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DNA Methylation
DNA methylation is a biological process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without changing the sequence. When located in a gene promoter (genetics), promoter, DNA methylation typically acts to repress gene Transcription (genetics), transcription. In mammals, DNA methylation is essential for normal development and is associated with a number of key processes including genomic imprinting, X-chromosome inactivation, repression of transposable elements, aging, and carcinogenesis. As of 2016, two nucleobases have been found on which natural, enzymatic DNA methylation takes place: adenine and cytosine. The modified bases are N6-methyladenine,D. B. Dunn, J. D. Smith: "The occurrence of 6-methylaminopurine in deoxyribonucleic acids". In: ''Biochem J.'' 68(4), Apr 1958, S. 627–636. [//www.ncbi.nlm.nih.gov/pubmed/13522672?dopt=Abstract PMID 13522672]. . 5-methylcytosineB. F. Vanyushin, S. G. Tkacheva, A. N. Belozers ...
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