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Pseudorabies
Aujeszky's disease, usually called pseudorabies in the United States, is a viral disease in swine that is endemic in most parts of the world. It is caused by pseudorabies virus (PRV). Aujeszky's disease is considered to be the most economically important viral disease of swine in areas where classical swine fever ( hog cholera) has been eradicated. Other mammals, such as cattle, sheep, goats, cats, dogs, and raccoons, are also susceptible. The disease is usually fatal in these animal species. Research on PRV in pigs has pioneered animal disease control with genetically modified vaccines. PRV is now used in model studies of basic processes during lytic herpesvirus infection, and for unravelling molecular mechanisms of herpesvirus neurotropism. History In 1902, a Hungarian veterinarian, Aladár Aujeszky, demonstrated a new infectious agent in a dog, ox, and cat, and showed it caused the same disease in swine and rabbits. In the following decades the infection was found in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aladár Aujeszky
Aladár Aujeszky (11 January 1869 Pest – 9 March 1933 Budapest) was a Hungarian veterinary pathologist, professor of bacteriology and microbiologist, noted for his work on pseudorabies. Pseudorabies (also known as PRV, Aujeszky's disease, infectious bulbar paralysis, or mad itch), is caused by a virus with icosahedral symmetry and belongs to the subfamily Alphaherpesvirinae within the family Herpesviridae. This subfamily has a wide host range and attacks the peripheral nervous system The peripheral nervous system (PNS) is one of two components that make up the nervous system of Bilateria, bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia, which lie outside t ... of the host. It was first described in 1813 in a situation where cattle and pigs shared a stable. In 1909 Weiss found that pigs are the reservoir host of the virus, and that, even though other species such as cattle, sheep, cats, dogs, goats, hor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Neuronal Tracing
Viral neuronal tracing is the use of a virus to trace neural pathways, providing a self-replicating tracer. Viruses have the advantage of self-replication over molecular tracers but can also spread too quickly and cause degradation of neural tissue. Viruses that can infect the nervous system, called neurotropic viruses, spread through spatially close assemblies of neurons through synapses, allowing for their use in studying functionally connected neural networks. The use of viruses to label functionally connected neurons stems from the work and bioassay developed by Albert Sabin. Subsequent research allowed for the incorporation of immunohistochemical techniques to systematically label neuronal connections. To date, viruses have been used to study multiple circuits in the nervous system. Neuronal Cartography The individual connections of neurons have long evaded neuroanatomists. Neuronal tracing methods offer an unprecedented view into the morphology and connectivity of neura ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ELISA
The enzyme-linked immunosorbent assay (ELISA) (, ) is a commonly used analytical biochemistry assay, first described by Eva Engvall and Peter Perlmann in 1971. The assay is a solid-phase type of enzyme immunoassay (EIA) to detect the presence of a ligand (commonly an amino acid) in a liquid sample using antibodies directed against the ligand to be measured. ELISA has been used as a medical diagnosis, diagnostic tool in medicine, plant pathology, and biotechnology, as well as a quality control check in various industries. In the most simple form of an ELISA, antigens from the sample to be tested are attached to a surface. Then, a matching antibody is applied over the surface so it can bind the antigen. This antibody is linked to an enzyme, and then any unbound antibodies are removed. In the final step, a substance containing the enzyme's Enzyme substrate, substrate is added. If there was binding, the subsequent reaction produces a detectable signal, most commonly a color change. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neural Network
A neural network is a group of interconnected units called neurons that send signals to one another. Neurons can be either biological cells or signal pathways. While individual neurons are simple, many of them together in a network can perform complex tasks. There are two main types of neural networks. *In neuroscience, a '' biological neural network'' is a physical structure found in brains and complex nervous systems – a population of nerve cells connected by synapses. *In machine learning, an '' artificial neural network'' is a mathematical model used to approximate nonlinear functions. Artificial neural networks are used to solve artificial intelligence problems. In biology In the context of biology, a neural network is a population of biological neurons chemically connected to each other by synapses. A given neuron can be connected to hundreds of thousands of synapses. Each neuron sends and receives electrochemical signals called action potentials to its conne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilateria, bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and Coelenterata, diploblasts. It is a structure composed of nervous tissue positioned along the Anatomical_terms_of_location#Rostral,_cranial,_and_caudal, rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain, though precursor structures exist in onychophorans, gastropods and lancelets. The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iatrogenic
Iatrogenesis is the causation of a disease, a harmful complication, or other ill effect by any medical activity, including diagnosis, intervention, error, or negligence." Iatrogenic", ''Merriam-Webster.com'', Merriam-Webster, Inc., accessed 27 Jun 2020. First used in this sense in 1924, the term was introduced to sociology in 1976 by Ivan Illich, alleging that industrialized societies impair quality of life by overmedicalizing life."iatrogenesis" ''A Dictionary of Sociology'', . updated 31 May 2020. Iatrogenesis may thus include mental suffering via medical beliefs or a practitioner's statements. Some iatrogen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mink
Mink are dark-colored, semiaquatic, carnivorous mammals of the genera ''Neogale'' and '' Mustela'' and part of the family Mustelidae, which also includes weasels, otters, and ferrets. There are two extant species referred to as "mink": the American mink and the European mink. The extinct sea mink was related to the American mink but was much larger. The American mink's fur has been highly prized for use in clothing. Their treatment on fur farms has been a focus of animal rights and animal welfare activism. American mink have established populations in Europe (including Great Britain and Denmark) and South America. Some people believe this happened after the animals were released from mink farms by animal rights activists, or otherwise escaped from captivity. In the UK, under the Wildlife and Countryside Act 1981, it is illegal to release mink into the wild. In some countries, any live mink caught in traps must be humanely killed. American mink are believed by some to hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coyotes
The coyote (''Canis latrans''), also known as the American jackal, prairie wolf, or brush wolf, is a species of canine native to North America. It is smaller than its close relative, the gray wolf, and slightly smaller than the closely related eastern wolf and red wolf. It fills much of the same ecological niche as the golden jackal does in Eurasia; however, the coyote is generally larger. The coyote is listed as least concern by the International Union for Conservation of Nature, due to its wide distribution and abundance throughout North America. The species is versatile, able to adapt to and expand into environments modified by humans; urban coyotes are common in many cities. The coyote was sighted in eastern Panama (across the Panama Canal from their home range) for the first time in 2013. The coyote has 19 recognized subspecies. The average male weighs and the average female . Their fur color is predominantly light gray and red or fulvous interspersed with black and w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Florida Panther
The Florida panther is a North American cougar (''P. c. couguar'') population in South Florida. It lives in pinelands, tropical hardwood hammocks and mixed freshwater swamp forests. Its range includes the Big Cypress National Preserve, Everglades National Park, Florida Panther National Wildlife Refuge, Picayune Strand State Forest, as well as rural communities in the counties of Collier County, Florida, Collier, Hendry County, Florida, Hendry, Hardee County, Florida, Hardee, DeSoto County, Florida, Desoto, Lee County, Florida, Lee, Miami-Dade County, Florida, Miami-Dade, and Monroe County, Florida, Monroe County. It is the only confirmed cougar population in the Eastern United States, and currently occupies 5% of its historic range. As of 2024, about 200 individuals are left in the wild. Description Florida panthers are spotted at birth, and typically have blue eyes. As the panther grows, the spots fade and the coat becomes completely tan, while the eyes typically take on a yell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Black Bear
The American black bear (''Ursus americanus''), or simply black bear, is a species of medium-sized bear which is Endemism, endemic to North America. It is the continent's smallest and most widely distributed bear species. It is an omnivore, with a diet varying greatly depending on season and location. It typically lives in largely forested areas; it will leave forests in search of food and is sometimes attracted to human communities due to the immediate availability of food. The International Union for Conservation of Nature (IUCN) lists the American black bear as a least-concern species because of its widespread distribution and a large population, estimated to be twice that of all other bear species combined. Along with the brown bear (''Ursus arctos''), it is one of the two modern bear species not considered by the IUCN to be globally threatened with extinction. Taxonomy and evolution The American black bear is not closely related to the brown bear or polar bear, though all ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
