Protocells
A protocell (or protobiont) is a self-organized, endogenously ordered, spherical collection of lipids proposed as a rudimentary precursor to cells during the origin of life. A central question in evolution is how simple protocells first arose and how their progeny could diversify, thus enabling the accumulation of novel biological emergences over time (i.e. biological evolution). Although a functional protocell has not yet been achieved in a laboratory setting, the goal to understand the process appears well within reach. A protocell is a pre-cell in abiogenesis, and was a contained system consisting of simple biologically relevant molecules like ribozymes, and encapsulated in a simple membrane structure – isolating the entity from the environment and other individuals – thought to consist of simple fatty acids, mineral structures, or rock-pore structures. Overview Compartmentalization was important in the origin of life. Membranes form enclosed compartments that are separa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Abiogenesis
Abiogenesis is the natural process by which life arises from non-living matter, such as simple organic compounds. The prevailing scientific hypothesis is that the transition from non-living to living entities on Earth was not a single event, but a process of increasing complexity involving the formation of a habitable planet, the prebiotic synthesis of organic molecules, molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. The transition from non-life to life has never been observed experimentally, but many proposals have been made for different stages of the process. The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It primarily uses tools from biology and chemistry, with more recent approaches attempting a synthesis of many sciences. Life functions through the specialized chemistry of carbon and water, and builds largely ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Last Universal Common Ancestor
The last universal common ancestor (LUCA) is the hypothesized common ancestral cell from which the three domains of life, the Bacteria, the Archaea, and the Eukarya originated. The cell had a lipid bilayer; it possessed the genetic code and ribosomes which translated from DNA or RNA to proteins. Although the timing of the LUCA is not able to be definitively constrained, most studies suggest that the LUCA existed by or prior to 3.5 billion years ago, and possibly as early as 4.3 billion years ago or earlier. The nature of this point or stage of divergence remains a topic of research. All earlier forms of life preceding this divergence and all extant organisms are generally thought to share common ancestry. On the basis of a formal statistical test, this theory of a universal common ancestry (UCA) is supported versus competing multiple-ancestry hypotheses. The first universal common ancestor (FUCA) is a hypothetical non-cellular ancestor to LUCA and other now-extinct s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Self-organization
Self-organization, also called spontaneous order in the social sciences, is a process where some form of overall order and disorder, order arises from local interactions between parts of an initially disordered system. The process can be spontaneous when sufficient energy is available, not needing control by any external agent. It is often triggered by seemingly random Statistical fluctuations, fluctuations, amplified by positive feedback. The resulting organization is wholly decentralized, :wikt:distribute, distributed over all the components of the system. As such, the organization is typically Robustness, robust and able to survive or self-healing material, self-repair substantial perturbation theory, perturbation. Chaos theory discusses self-organization in terms of islands of predictability in a sea of chaotic unpredictability. Self-organization occurs in many physics, physical, chemistry, chemical, biology, biological, robotics, robotic, and cognitive systems. Examples of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tibor Gánti
Tibor Gánti (10 September 1933 – 15 April 2009) was a Hungarian theoretical biologist and biochemist, who is best known for his theory of the chemoton, a model for defining the minimal nature of life. He taught industrial biochemistry at Faculty of Science of the Eötvös University, and theoretical biology at University of Gödöllő, József Attila University, and Eötvös University. Early life and education Tibor Gánti worked as laboratory assistant at the Bacteriological Laboratory, Factory of Canned Food at Dunakeszi from 1951-1952. He then moved to Photochemical Research Institute of Vác in 1953-1954. From 1958 to 1965 he was the head of Yeast Laboratory, Yeast Factory, Budapest. In the meantime he completed a diploma in chemical engineering from the Technical University of Budapest in 1958, and a Dr. techn. (PhD) in 1962. Between 1965 and 1974 he was the head of biochemical department at the Reanal Factory of Laboratory Chemicals in Budapest. He was awar ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Metabolism
Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks of proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their Structures#Biological, structures, and respond to their environments. The word ''metabolism'' can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. Metabolic reactions may be categorized as ''catabolic''—the ''breaking down'' of compounds (for example, of glucose to pyruvate by c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Entropy
Entropy is a scientific concept, most commonly associated with states of disorder, randomness, or uncertainty. The term and the concept are used in diverse fields, from classical thermodynamics, where it was first recognized, to the microscopic description of nature in statistical physics, and to the principles of information theory. It has found far-ranging applications in chemistry and physics, in biological systems and their relation to life, in cosmology, economics, sociology, weather science, climate change and information systems including the transmission of information in telecommunication. Entropy is central to the second law of thermodynamics, which states that the entropy of an isolated system left to spontaneous evolution cannot decrease with time. As a result, isolated systems evolve toward thermodynamic equilibrium, where the entropy is highest. A consequence of the second law of thermodynamics is that certain processes are irreversible. The thermodynami ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Second Law Of Thermodynamics
The second law of thermodynamics is a physical law based on Universal (metaphysics), universal empirical observation concerning heat and Energy transformation, energy interconversions. A simple statement of the law is that heat always flows spontaneously from hotter to colder regions of matter (or 'downhill' in terms of the temperature gradient). Another statement is: "Not all heat can be converted into Work (thermodynamics), work in a cyclic process."Young, H. D; Freedman, R. A. (2004). ''University Physics'', 11th edition. Pearson. p. 764. The second law of thermodynamics establishes the concept of entropy as a physical property of a thermodynamic system. It predicts whether processes are forbidden despite obeying the requirement of conservation of energy as expressed in the first law of thermodynamics and provides necessary criteria for spontaneous processes. For example, the first law allows the process of a cup falling off a table and breaking on the floor, as well as allowi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phospholipids Aqueous Solution Structures
Phospholipids are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids typically have omega-3 fatty acids EPA and DHA integrated as part of the phospholipid molecule. The phosphate group can be modified with simple organic molecules such as choline, ethanolamine or serine. Phospholipids are a key component of all cell membranes. They can form lipid bilayers because of their amphiphilic characteristic. In eukaryotes, cell membranes also contain another class of lipid, sterol, interspersed among the phospholipids. The combination provides fluidity in two dimensions combined with mechanical strength against rupture. Purified phospholipids are produced commercially and have found applications in nanotechnology and materials science. The first phospholipid identified in 1847 as such in biological tissues was lecithi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Unit Of Selection
A unit of selection is a biological entity within the hierarchy of biological organization (for example, an entity such as: a self-replicating molecule, a gene, a cell, an organism, a group, or a species) that is subject to natural selection. There is debate among evolutionary biologists about the extent to which evolution has been shaped by selective pressures acting at these different levels.Okasha, S. (2006) ''Evolution and the levels of selection''. Oxford University Press. There is debate over the relative importance of the units themselves. For instance, is it group or individual selection that has driven the evolution of altruism? Where altruism reduces the fitness of ''individuals'', individual-centered explanations for the evolution of altruism become complex and rely on the use of game theory, for instance; see kin selection and group selection. There also is debate over the definition of the units themselves, and the roles for selection and replication, and whether ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Natural Selection
Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the Heredity, heritable traits characteristic of a population over generations. Charles Darwin popularised the term "natural selection", contrasting it with selective breeding, artificial selection, which is intentional, whereas natural selection is not. Genetic diversity, Variation of traits, both Genotype, genotypic and phenotypic, exists within all populations of organisms. However, some traits are more likely to facilitate survival and reproductive success. Thus, these traits are passed the next generation. These traits can also become more Allele frequency, common within a population if the environment that favours these traits remains fixed. If new traits become more favoured due to changes in a specific Ecological niche, niche, microevolution occurs. If new traits become more favoured due to changes in the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Autocatalytic
In chemistry, a chemical reaction is said to be autocatalytic if one of the reaction products is also a catalyst for the same reaction. Many forms of autocatalysis are recognized.Steinfeld J.I., Francisco J.S. and Hase W.L. ''Chemical Kinetics and Dynamics'' (2nd ed., Prentice-Hall 1999) pp. 151–2 A ''set'' of chemical reactions can be said to be "collectively autocatalytic" if a number of those reactions produce, as reaction products, catalysts for enough of the other reactions that the entire set of chemical reactions is self-sustaining given an input of energy and food molecules (see autocatalytic set). Examples Acid-catalyzed hydrolysis of esters produces carboxylic acids that also catalyze the same reaction. Indeed, the observation of an accelerating hydrolysis of gamma valerolactone to gamma-hydroxyvaleric acid led to the introduction of the concept of autocatalysis in 1890. The oxidation of hydrocarbons by air or oxygen is the basis of autoxidation. Like many radic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |