Primary Amoebic Meningoencephalitis
Naegleriasis, also known as primary amoebic meningoencephalitis (PAM), is an almost invariably fatal infection of the brain by the free-living protozoan '' Naegleria fowleri''. Symptoms include headache, fever, nausea, vomiting, a stiff neck, confusion, hallucinations and seizures. Symptoms progress rapidly over around five days with characteristics of both meningitis and encephalitis, making it a type of meningoencephalitis. Death usually results within one to two weeks of symptom onset. ''N. fowleri'' is typically found in warm bodies of fresh water, such as ponds, lakes, rivers and hot springs. It is found in an amoeboid, temporary flagellate stage or microbial cyst in soil, poorly maintained municipal water supplies, water heaters, near warm-water discharges of industrial plants and in poorly chlorinated or unchlorinated swimming pools. There is no evidence of it living in salt water. As the disease is rare, it is often not considered during diagnosis. Although infec ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fluorescent Antibody
Immunofluorescence (IF) is a light microscopy-based technique that allows detection and localization of a wide variety of target biomolecules within a cell or tissue at a quantitative level. The technique utilizes the binding specificity of antibodies and antigens. The specific region an antibody recognizes on an antigen is called an epitope. Several antibodies can recognize the same epitope but differ in their binding affinity. The antibody with the higher affinity for a specific epitope will surpass antibodies with a lower affinity for the same epitope. By conjugating the antibody to a fluorophore, the position of the target biomolecule is visualized by exciting the fluorophore and measuring the emission of light in a specific predefined wavelength using a fluorescence microscope. It is imperative that the binding of the fluorophore to the antibody itself does not interfere with the immunological specificity of the antibody or the binding capacity of its antigen. Immunofluoresc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Headache
A headache, also known as cephalalgia, is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of Depression (mood), depression in those with severe headaches. Headaches can occur as a result of many conditions. There are a number of different classification systems for headaches. The most well-recognized is that of the International Headache Society, which classifies it into more than 150 types of Primary headache disorder, primary and secondary headaches. Causes of headaches may include dehydration; fatigue; sleep deprivation; Stress (biology), stress; the effects of medications (overuse) and recreational drugs, including withdrawal; viral infections; loud noises; head injury; rapid ingestion of a very cold food or beverage; and dental or sinus issues (such as sinusitis). Treatment of a headache depends on the underlying cause, but commonly involves analgesic, pain medication (esp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Manufacturing Plant
A factory, manufacturing plant or production plant is an Industry (manufacturing), industrial facility, often a complex consisting of several buildings filled with Outline of industrial machinery, machinery, where workers manufacturing, manufacture items or operate machines which Process Manufacturing, process each item into another. They are a critical part of modern Production (economics), economic production, with the majority of the world's goods being created or processed within factories. Factories arose with the introduction of machinery during the Industrial Revolution, when the Capital (economics), capital and space requirements became too great for Putting-out system, cottage industry or workshops. Early factories that contained small amounts of machinery, such as one or two spinning mules, and fewer than a dozen workers have been called "glorified workshops". Most modern factories have large warehouses or warehouse-like facilities that contain heavy equipment used fo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Microbial Cyst
A microbial cyst is a resting or dormant stage of a microorganism, that can be thought of as a state of suspended animation in which the metabolic processes of the cell are slowed and the cell ceases all activities like feeding and locomotion. Many groups of single-celled, microscopic organisms, or microbes, possess the ability to enter this dormant state. Encystment, the process of cyst formation, can function as a method for dispersal and as a way for an organism to survive in unfavorable environmental conditions. These two functions can be combined when a microbe needs to be able to survive harsh conditions between habitable environments (such as between hosts) in order to disperse. Cysts can also be sites for nuclear reorganization and cell division, and in parasitic species they are often the infectious stage between hosts. When the encysted microbe reaches an environment favorable to its growth and survival, the cyst wall breaks down by a process known as excystation. E ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Flagellate
A flagellate is a cell or organism with one or more whip-like appendages called flagella. The word ''flagellate'' also describes a particular construction (or level of organization) characteristic of many prokaryotes and eukaryotes and their means of motion. The term presently does not imply any specific relationship or classification of the organisms that possess flagella. However, several derivations of the term "flagellate" (such as " dinoflagellate" and " choanoflagellate") are more formally characterized. Form and behavior Flagella in eukaryotes are supported by microtubules in a characteristic arrangement, with nine fused pairs surrounding two central singlets. These arise from a basal body. In some flagellates, flagella direct food into a cytostome or mouth, where food is ingested. Flagella role in classifying eukaryotes. Among protoctists and microscopic animals, a flagellate is an organism with one or more flagella. Some cells in other animals may be flage ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Amoeboid
An amoeba (; less commonly spelled ameba or amœba; : amoebas (less commonly, amebas) or amoebae (amebae) ), often called an amoeboid, is a type of cell or unicellular organism with the ability to alter its shape, primarily by extending and retracting pseudopods. Amoebae do not form a single taxonomic group; instead, they are found in every major lineage of eukaryotic organisms. Amoeboid cells occur not only among the protozoa, but also in fungi, algae, and animals. Microbiologists often use the terms "amoeboid" and "amoeba" interchangeably for any organism that exhibits amoeboid movement. In older classification systems, most amoebae were placed in the class or subphylum Sarcodina, a grouping of single-celled organisms that possess pseudopods or move by protoplasmic flow. However, molecular phylogenetic studies have shown that Sarcodina is not a monophyletic group whose members share common descent. Consequently, amoeboid organisms are no longer classified together in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hot Spring
A hot spring, hydrothermal spring, or geothermal spring is a Spring (hydrology), spring produced by the emergence of Geothermal activity, geothermally heated groundwater onto the surface of the Earth. The groundwater is heated either by shallow bodies of magma (molten rock) or by circulation through fault (geology), faults to hot rock deep in the Earth's crust. Hot spring water often contains large amounts of dissolved minerals. The chemistry of hot springs ranges from acid sulfate springs with a pH as low as 0.8, to alkaline chloride springs saturated with silica, to bicarbonate springs saturated with carbon dioxide and carbonate minerals. Some springs also contain abundant dissolved iron. The minerals brought to the surface in hot springs often feed communities of extremophiles, microorganisms adapted to extreme conditions, and it is possible that life on Earth had its origin in hot springs. Humans have made use of hot springs for bathing, relaxation, or medical therapy for th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Meningoencephalitis
Meningoencephalitis (; from ; ; and the medical suffix ''-itis'', "inflammation"), also known as herpes meningoencephalitis, is a medical condition that simultaneously resembles both meningitis, which is an infection or inflammation of the meninges, and encephalitis, which is an infection or inflammation of the brain tissue. Signs and symptoms Signs of meningoencephalitis include unusual behavior, personality changes, nausea, and thinking problems. Symptoms may include headache, fever, pain in neck movement, light sensitivity, and seizure. Causes The organisms which cause meningoencephalitis include bacterial pathogens, protozoans, and viruses. Bacterial Veterinarians have observed meningoencephalitis in animals infected with listeriosis, caused by the pathogenic bacteria '' L. monocytogenes''. Meningitis and encephalitis already present in the brain or spinal cord of an animal may form simultaneously into meningeoencephalitis. The bacteria commonly targets the sensiti ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Encephalitis
Encephalitis is inflammation of the Human brain, brain. The severity can be variable with symptoms including reduction or alteration in consciousness, aphasia, headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing. Causes of encephalitis include viruses such as herpes simplex virus and rabies virus as well as bacteria, fungi, or parasites. Other causes include autoimmune diseases and certain medications. In many cases the cause remains unknown. Risk factors include a immunosuppression, weak immune system. Diagnosis is typically based on symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid. Certain types are preventable with vaccines. Treatment may include antiviral medications (such as acyclovir), anticonvulsants, and corticosteroids. Treatment generally takes place in hospital. Some people require artificial respiration. Once ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hallucination
A hallucination is a perception in the absence of an external stimulus that has the compelling sense of reality. They are distinguishable from several related phenomena, such as dreaming ( REM sleep), which does not involve wakefulness; pseudohallucination, which does not mimic real perception, and is accurately perceived as unreal; illusion, which involves distorted or misinterpreted real perception; and mental imagery, which does not mimic real perception, and is under voluntary control. Hallucinations also differ from " delusional perceptions", in which a correctly sensed and interpreted stimulus (i.e., a real perception) is given some additional significance. Hallucinations can occur in any sensory modality— visual, auditory, olfactory, gustatory, tactile, proprioceptive, equilibrioceptive, nociceptive, thermoceptive and chronoceptive. Hallucinations are referred to as multimodal if multiple sensory modalities occur. A mild form of hallucination is known as ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Confusion
In psychology, confusion is the quality or emotional state of being bewildered or unclear. The term "acute mental confusion"''Confusion Definition'' on Oxford Dictionaries. is often used interchangeably with delirium in the '' International Statistical Classification of Diseases and Related Health Problems'' and the '' [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stiff Neck
Neck stiffness, stiff neck and nuchal rigidity are terms often used interchangeably to describe the medical condition when one experiences discomfort or pain when trying to turn, move, or flex the neck. Possible causes include muscle strain or sprain, cervical spine disorder, meningitis, and subarachnoid hemorrhage. Nuchal rigidity due to irritation of the lining of the brain and spinal cord is one of the main symptoms of meningitis. stiff neckis the body's way of reminding us that we've been carrying more than just our head on our shoulders. See also * Neck pain * Torticollis Torticollis, also known as wry neck, is an extremely painful, dystonic condition defined by an abnormal, asymmetrical head or neck position, which may be due to a variety of causes. The term ''torticollis'' is derived . The most common case ha ... References Human head and neck {{Med-sign-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |