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Pityriasis Rubra Pilaris
Pityriasis rubra pilaris refers to a group of chronic disorders characterized by reddish orange, scaling plaques and keratotic follicular papules.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. . Symptoms may include reddish-orange patches (Latin: ''rubra'') on the skin, severe flaking (Latin: ''pityriasis''), uncomfortable itching, thickening of the skin on the feet and hands, and thickened bumps around hair follicles (Latin: ''pilus'' for hair). For some, early symptoms may also include generalized swelling of the legs, feet and other parts of the body. PRP has a varied clinical progression and a varied rate of improvement. There is currently no known cause or cure for PRP. It was first described by Marie-Guillaume-Alphonse Devergie in 1856, and the condition is also known as Devergie's disease. Diagnosis Classification Dr. W.A.D. Griffiths, from Great Britain, classified six forms of PRP in the early 1980s. At this time, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Papule
A papule is a small, well-defined bump in the skin lesion, skin. It may have a rounded, pointed or flat top, and may have a umbilication, dip. It can appear with a Peduncle (anatomy), stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some have Crust (dermatology), crusts or Scale (dermatology), scales. A papule can be flesh colored, yellow, white, brown, red, blue or purplish. There may be just one or many, and they may occur irregularly in different parts of the body or appear in clusters. It does not contain fluid but may progress to a pustule or vesicle (dermatology), vesicle. A papule is smaller than a Nodule (medicine), nodule; it can be as tiny as a pinhead and is typically less than 1 cm in width, according to some sources, and 0.5 cm according to others. When merged together, it appears as a plaque. A papule's colour might indicate its cause, such as white in Milium (dermatology), milia, red in eczema, yellowish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pityriasis
Pityriasis commonly refers to flaking (or scaling) of the skin. The word comes from the Greek πίτυρον 'bran'. Classification Types include: * Pityriasis alba, dry, fine-scaled, pale patches on the face * Pityriasis lichenoides chronica, caused by a hypersensitivity reaction to infectious agents * Pityriasis lichenoides et varioliformis acuta, a disease of the immune system * Pityriasis rosea, a type of skin rash ** Pityriasis circinata, * Pityriasis rubra pilaris, reddish-orange patches (Latin: ''rubra'') on the skin * Pityriasis versicolor, a skin eruption on the trunk and proximal extremities, usually caused by a fungus * Dandruff, historically called ''Pityriasis capitis'' * Pityriasis amiantacea, condition of the scalp in which thick tenaciously adherent scale infiltrates and surrounds the base of a group of scalp hairs See also * Desquamation * List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system cove ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hair Follicle
The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. This complex interaction induces the hair follicle to produce different types of hair as seen on different parts of the body. For example, terminal hairs grow on the scalp and lanugo hairs are seen covering the bodies of fetuses in the uterus and in some newborn babies. The process of hair growth occurs in distinct sequential stages: ''anagen'' is the active growth phase, ''catagen'' is the regression of the hair follicle phase, ''telogen'' is the resting stage, ''exogen'' is the active shedding of hair phase and ''kenogen'' is the phase between the empty hair follicle and the growth of new hair. The function of hair in humans has long been a subject of interest and continues to be an impor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marie-Guillaume-Alphonse Devergie
Marie-Guillaume-Alphonse Devergie (February 15, 1798 – October 2, 1879) was a French dermatologist born in Paris. In 1834 he became a physician of Parisian hospitals (''médecin des hôpitaux''), and in 1840 succeeded Laurent-Théodore Biett (1781–1840) at the Hôpital Saint-Louis, where he practiced medicine until his retirement. During his career he was also associated with the Hôpitaux Bicêtre and St. Antoine. In 1874 he was elected president of the '' Académie de Médecine''. In 1856 Devergie was the first to describe a chronic papulosquamous disorder known as pityriasis rubra pilaris, also referred to as "Devergie's disease", a term introduced by Ernest Henri Besnier (1831-1909) in 1889. In 1854 he published an important textbook on skin diseases titled ''Traité pratique des maladies de la peau''. When he retired, Devergie donated his collection of dermatological watercolors to the Parisian hospital administration. This donation was instrumental in creation of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Britain
Great Britain is an island in the North Atlantic Ocean off the north-west coast of continental Europe, consisting of the countries England, Scotland, and Wales. With an area of , it is the largest of the British Isles, the List of European islands by area, largest European island, and the List of islands by area, ninth-largest island in the world. It is dominated by a maritime climate with narrow temperature differences between seasons. The island of Ireland, with an area 40 per cent that of Great Britain, is to the west – these islands, along with over List of islands of the British Isles, 1,000 smaller surrounding islands and named substantial rocks, comprise the British Isles archipelago. Connected to mainland Europe until 9,000 years ago by a land bridge now known as Doggerland, Great Britain has been inhabited by modern humans for around 30,000 years. In 2011, it had a population of about , making it the world's List of islands by population, third-most-populous islan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Disorder
A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosome abnormality. Although polygenic disorders are the most common, the term is mostly used when discussing disorders with a single genetic cause, either in a gene or chromosome. The mutation responsible can occur spontaneously before embryonic development (a ''de novo'' mutation), or it can be inherited from two parents who are carriers of a faulty gene ( autosomal recessive inheritance) or from a parent with the disorder (autosomal dominant inheritance). When the genetic disorder is inherited from one or both parents, it is also classified as a hereditary disease. Some disorders are caused by a mutation on the X chromosome and have X-linked inheritance. Very few disorders are inherited on the Y chromosome or mitochondrial DNA (due to their size). There are well over 6,000 known ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis (skin), epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. Embryology, In the embryo, the epidermis, hair, and glands form from the ectod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
