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Pit Vipers
The Crotalinae, commonly known as pit vipers,Mehrtens JM (1987). ''Living Snakes of the World in Color''. New York: Sterling Publishers. 480 pp. . or pit adders, are a subfamily of vipers found in Asia and the Americas. Like all other vipers, they are venomous. They are distinguished by the presence of a heat-sensing pit organ located between the eye and the nostril on both sides of the head. Currently, 23 genera and 155 species are recognized: These are also the only viperids found in the Americas. The groups of snakes represented here include rattlesnakes, lanceheads, and Asian pit vipers. The type genus for this subfamily is '' Crotalus'', of which the type species is the timber rattlesnake, ''C. horridus''. These snakes range in size from the diminutive hump-nosed viper, '' Hypnale hypnale'', that grows to a typical total length (including tail) of only , to the bushmaster, '' Lachesis muta'', a species known to reach a maximum total length of in length. This subfam ...
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Timber Rattlesnake
The timber rattlesnake (''Crotalus horridus''), also known Common name, commonly as the canebrake rattlesnake and the banded rattlesnake,Albert Hazen WWright AH, species:Anna Allen WWright AA (1957). ''Handbook of Snakes of the United States and Canada''. Ithaca and London: Comstock Publishing Associates, a division of Cornell University Press. (7th printing, 1985). 1,105 pp. (in two volumes). . (''Crotalus horridus'', pp. 956–966.) is a species of Crotalinae, pit viper in the Family (biology), family Viperidae. The species is native to the eastern United States. Like all other pit vipers, it is Venomous snake, venomous, with a very toxic bite. Its venom is extremely potent, both hemorrhagic and neurotoxic venom are present depending on population and location. ''C. horridus'' is the only rattlesnake species in most of the populous Northeastern United States and is second only to its relatives to the west, the Crotalus viridis, prairie rattlesnake, as the most northerly distri ...
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Lachesis Muta
''Lachesis muta'', also known as the Southern American bushmaster or Atlantic bushmaster, is a pit viper species found in South America, as well as the island of Trinidad in the Caribbean. Two subspecies are currently recognized, including the nominate subspecies described here. Taxonomy Two additional subspecies, ''L. m. melanocephala'' and ''L. m. stenophrys'', had earlier been recognized. However, both were elevated to species level by Zamudio and Green in 1997 (see '' L. melanocephala'' and '' L. stenophrys''). Subspecies Description Adults grow to an average of 2 to 2.5 m (6½-8 feet), although 3 m (10 feet) is not too unusual. The largest recorded specimen was 3.65 m (almost 12 feet) long, making the species the largest of all vipers and the longest venomous snake in the Western Hemisphere.Mehrtens JM (1987). ''Living Snakes of the World in Color''. New York: Sterling Publishers. 480 pp. . ''Lachesis muta'' is the third longest venomous snake in the world, exce ...
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Nebraska
Nebraska ( ) is a landlocked U.S. state, state in the Midwestern United States, Midwestern region of the United States. It borders South Dakota to the north; Iowa to the east and Missouri to the southeast, both across the Missouri River; Kansas to the south; Colorado to the southwest; and Wyoming to the west. Nebraska is the List of U.S. states and territories by area, 16th-largest state by land area, with just over . With a population of over 2 million as of 2024, it is the List of U.S. states and territories by population, 38th-most populous state and the List of states and territories of the United States by population density, eighth-least densely populated. Its List of capitals in the United States, capital is Lincoln, Nebraska, Lincoln, and its List of municipalities in Nebraska, most populous city is Omaha, Nebraska, Omaha, which is on the Missouri River. Nebraska was admitted into the United States in 1867, two years after the end of the American Civil War. The Nebras ...
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Early Miocene
The Early Miocene (also known as Lower Miocene) is a sub-epoch of the Miocene epoch (geology), Epoch made up of two faunal stage, stages: the Aquitanian age, Aquitanian and Burdigalian stages. The sub-epoch lasted from 23.03 ± 0.05 annum, Ma to 15.97 ± 0.05 Ma (million years ago). It was preceded by the Oligocene epoch. As the climate started to get cooler, the landscape started to change. New mammals evolved to replace the extinct animals of the Oligocene epoch. The first members of the hyena and weasel family started to evolve to replace the extinct ''Hyaenodon'', entelodonts and bear-dogs. The chalicotheres survived the Oligocene epoch. A new genus of entelodont called ''Daeodon'' evolved in order to adapt to the new habitats and hunt the new prey animals of the Early Miocene epoch; it quickly became the top predator of North America. But it became extinct due to competition from ''Amphicyon'', a newcomer from Eurasia. ''Amphicyon'' bested ''Daeodon'' because the bear-dog's la ...
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Rangefinder
A rangefinder (also rangefinding telemeter, depending on the context) is a device used to Length measurement, measure distances to remote objects. Originally optical devices used in surveying, they soon found applications in other fields, such as photography, the military, and space travel. They were especially useful for finding the range of a target, such as in naval gunnery and anti-aircraft artillery. The word ''telemeter'' is derived . Designs The first rangefinder telemeter was invented by James Watt in 1769 and put to use in 1771 in surveying canals. Watt called his instrument a micrometer, a term now used with a different meaning in engineering (the micrometer screw gauge). It consisted of two parallel reticle, hairs in the focal plane of a telescope eyepiece crossing an upright hair. At the point to be measured, two sliding targets on a surveyor's rod were adjusted to align with the hairs in the telescope. The distance to the rod could then be determined from th ...
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Acetylcholine Esterase
Acetylcholinesterase ( HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters: : acetylcholine + H2O = choline + acetate It is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate cholinergic synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Enzyme structure and mechanism AChE is a hydrolase that hydrolyzes choline esters. It has a very high catalytic activity—each molecule of AChE degrades about 5,000 molecules of acetylcholine (ACh) per second, approaching the limit allowed by diffusion of the substrate. The active site ...
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Esterase
In biochemistry, an esterase is a class of enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis (and as such, it is a type of hydrolase). A wide range of different esterases exist that differ in their substrate specificity, their protein structure, and their biological function. EC classification/list of enzymes * ''EC 3.1.1'': Carboxylic ester hydrolases ** Acetylesterase (EC 3.1.1.6), splits off acetyl groups *** Cholinesterase **** Acetylcholinesterase, inactivates the neurotransmitter acetylcholine **** Pseudocholinesterase, broad substrate specificity, found in the blood plasma and in the liver ** Pectinesterase (EC 3.1.1.11), clarifies fruit juices * ''EC 3.1.2'': Thiolester hydrolases ** Thioesterase *** Ubiquitin carboxy-terminal hydrolase L1 * ''EC 3.1.3'': Phosphoric monoester hydrolases ** Phosphatase (EC 3.1.3.x), hydrolyses phosphoric acid monoesters into a phosphate ion and an alcohol *** Alkaline phosp ...
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Monoamine Oxidase
Monoamine oxidases (MAO) () are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. The first such enzyme was discovered in 1928 by Mary Bernheim in the liver and was named tyramine oxidase. The MAOs belong to the protein family of flavin-containing amine oxidoreductases. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs. Subtypes and tissue distribution In humans there are two types of MAO: MAO-A and MAO-B. * Both are found in neurons and astroglia. * Outside the central nervous system: ** MAO-A is also found in the liver, pulmonary vascular end ...
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Adenosine Triphosphate
Adenosine triphosphate (ATP) is a nucleoside triphosphate that provides energy to drive and support many processes in living cell (biology), cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all known forms of life, it is often referred to as the "molecular unit of currency" for intracellular energy transfer. When consumed in a Metabolism, metabolic process, ATP converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). Other processes regenerate ATP. It is also a Precursor (chemistry), precursor to DNA and RNA, and is used as a coenzyme. An average adult human processes around 50 kilograms (about 100 mole (unit), moles) daily. From the perspective of biochemistry, ATP is classified as a nucleoside triphosphate, which indicates that it consists of three components: a nitrogenous base (adenine), the sugar ribose, and the Polyphosphate, triphosphate. Structure ATP consists of three parts: a sugar, an amine base ...
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Mitochondria
A mitochondrion () is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'', meaning a thread-like granule, was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase popularized by Philip Siekevitz in a 1957 ''Scientific American'' article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). The multicellular animal '' Henneguya salminicola'' is known to have retained mitochondrion-related organelles despite a complete loss of their mitochondrial genome. A large number of unicellular organisms, such as microspo ...
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Pythonidae
The Pythonidae, commonly known as pythons, are a Family (biology), family of Venomous snake, nonvenomous snakes found in Africa, Asia, and Australia. Among its members are some of the largest snakes in the world. Ten Genus, genera and 39 species are currently recognized. Being naturally non-venomous, pythons must constrict their prey to induce cardiac arrest prior to consumption. Pythons will typically strike at and bite their prey of choice to gain hold of it; they then must use physical strength to constrict their prey, by coiling their muscular bodies around the animal, effectively suffocating it before swallowing whole. This is in stark contrast to venomous snakes such as the rattlesnake, for example, which delivers a swift, venomous bite but releases, waiting as the prey succumbs to envenomation before being consumed. Collectively, the pythons are well-documented and studied as constrictors, much like other non-venomous snakes, including the Boidae, boas and even kingsnakes ...
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Boidae
The Boidae, commonly known as boas or boids, are a family of nonvenomous snakes primarily found in the Americas, as well as Africa, Europe, Asia, and some Pacific islands. Boas include some of the world's largest snakes, with the green anaconda of South America being the heaviest and second-longest snake known; in general, adults are medium to large in size, with females usually larger than the males. Six subfamilies comprising 14-15 genera and 54-67 species are currently recognized. Description Like the pythons, boas have elongated supratemporal bones. The quadrate bones are also elongated, but not as much, while both are capable of moving freely so when they swing sideways to their maximum extent, the distance between the hinges of the lower jaw is greatly increased.Parker, H.W.; Grandison, A.G.C. 1977. ''Snakes – A Natural History''. Second Edition. British Museum (Natural History) and Cornell University Press. 108 pp. 16 plates. LCCCN 76-54625. (cloth), (paper). Bo ...
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