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PH Buffer
A buffer solution is a solution where the pH does not change significantly on dilution or if an acid or base is added at constant temperature. Its pH changes very little when a small amount of strong acid or base is added to it. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications. In nature, there are many living systems that use buffering for pH regulation. For example, the bicarbonate buffering system is used to regulate the pH of blood, and bicarbonate also acts as a buffer in the ocean. Principles of buffering Buffer solutions resist pH change because of a chemical equilibrium between the weak acid HA and its conjugate base A−: When some strong acid is added to an equilibrium mixture of the weak acid and its conjugate base, hydrogen ions (H+) are added, and the equilibrium is shifted to the left, in accordance with Le Chatelier's principle. Because of this, the hydrogen ion concentration increase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Strong Acid
Acid strength is the tendency of an acid, symbolised by the chemical formula , to dissociate into a hydron (chemistry), proton, , and an anion, . The Dissociation (chemistry), dissociation or ionization of a strong acid in solution is effectively complete, except in its most concentrated solutions. : Examples of strong acids are hydrochloric acid (), perchloric acid (), nitric acid () and sulfuric acid (). A weak acid is only partially dissociated, or is partly ionized in water with both the undissociated acid and its dissociation products being present, in solution, in Equilibrium chemistry, equilibrium with each other. : Acetic acid () is an example of a weak acid. The strength of a weak acid is quantified by its acid dissociation constant, K_a value. The strength of a weak organic chemistry, organic acid may depend on substituent effects. The strength of an inorganic chemistry, inorganic acid is dependent on the oxidation state for the atom to which the proton may be atta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Carbonic Acid
Carbonic acid is a chemical compound with the chemical formula . The molecule rapidly converts to water and carbon dioxide in the presence of water. However, in the absence of water, it is quite stable at room temperature. The interconversion of carbon dioxide and carbonic acid is related to the breathing cycle of animals and the acidification of natural waters. In biochemistry and physiology, the name "carbonic acid" is sometimes applied to aqueous solutions of carbon dioxide. These chemical species play an important role in the bicarbonate buffer system, used to maintain acid–base homeostasis. Terminology in biochemical literature In chemistry, the term "carbonic acid" strictly refers to the chemical compound with the formula . Some biochemistry literature effaces the distinction between carbonic acid and carbon dioxide dissolved in extracellular fluid. In physiology, carbon dioxide excreted by the lungs may be called ''volatile acid'' or ''respiratory acid''. Anh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Borate
A borate is any of a range of boron oxyanions, anions containing boron and oxygen, such as orthoborate , metaborate , or tetraborate ; or any salt of such anions, such as sodium metaborate, and borax . The name also refers to esters of such anions, such as trimethyl borate . Natural occurrence Borate ions occur, alone or with other anions, in many borate and borosilicate minerals such as borax, boracite, ulexite (boronatrocalcite) and colemanite. Borates also occur in seawater, contributing to the absorption of low-frequency sound in seawater. Common borate salts include sodium metaborate (NaBO2) and borax. Borax is soluble in water, so mineral deposits only occur in places with very low rainfall. Extensive deposits were found in Death Valley and shipped with twenty-mule teams from 1883 to 1889. In 1925, deposits were found at Boron, California on the edge of the Mojave Desert. The Atacama Desert in Chile also contains mineable borate concentrations. Borates ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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N-Cyclohexyl-2-aminoethanesulfonic Acid
CHES (''N''-cyclohexyl-2-aminoethanesulfonic acid) is a buffering agent. CHES buffers have a useful range of pH 8.6–10. It typically appears as a white crystalline powder. Effect of impurities Commercial prep of CHES (and other sulfonylethyl buffers like MES, BES, and PIPES Pipe(s), PIPE(S) or piping may refer to: Objects * Pipe (fluid conveyance), a hollow cylinder following certain dimension rules ** Piping, the use of pipes in industry * Smoking pipe ** Tobacco pipe * Half-pipe and quarter pipe, semi-circu ...) can contain a contaminant oligo(vinylsulfonic acid) (OVS), which is a polyanionic mimic of RNA, and can be a potent ( pM) inhibitor of RNA binding proteins and enzymes. References External links * Buffer solutions Sulfonic acids {{OrganicAcid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Potassium Dihydrogenphosphate
Monopotassium phosphate (MKP) (also, potassium dihydrogen phosphate, KDP, or monobasic potassium phosphate) is the inorganic compound with the formula KH2PO4. Together with dipotassium phosphate (K2HPO4.(H2O)x) it is often used as a fertilizer, food additive, and buffering agent. The salt often cocrystallizes with the dipotassium salt as well as with phosphoric acid. Single crystals are paraelectric at room temperature. At temperatures below , they become ferroelectric. Structure Monopotassium phosphate can exist in several polymorphs. At room temperature it forms paraelectric crystals with tetragonal symmetry. Upon cooling to it transforms to a ferroelectric phase of orthorhombic symmetry, and the transition temperature shifts up to when hydrogen is replaced by deuterium. Heating to changes its structure to monoclinic. When heated further, MKP decomposes, by loss of water, to potassium metaphosphate, , at . Manufacturing Monopotassium phosphate is produced by the ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Acetic Acid
Acetic acid , systematically named ethanoic acid , is an acidic, colourless liquid and organic compound with the chemical formula (also written as , , or ). Vinegar is at least 4% acetic acid by volume, making acetic acid the main component of vinegar apart from water. Historically, vinegar was produced from the third century BC and was likely the first acid to be produced in large quantities. Acetic acid is the second simplest carboxylic acid (after formic acid). It is an important Reagent, chemical reagent and industrial chemical across various fields, used primarily in the production of cellulose acetate for photographic film, polyvinyl acetate for wood Adhesive, glue, and synthetic fibres and fabrics. In households, diluted acetic acid is often used in descaling agents. In the food industry, acetic acid is controlled by the E number, food additive code E260 as an acidity regulator and as a condiment. In biochemistry, the acetyl group, derived from acetic acid, is funda ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Citric Acid
Citric acid is an organic compound with the formula . It is a Transparency and translucency, colorless Weak acid, weak organic acid. It occurs naturally in Citrus, citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, which occurs in the metabolism of all aerobic organisms. More than two million tons of citric acid Commodity chemicals, are manufactured every year. It is used widely as acidifier, flavoring, preservative, and chelating agent. A citrate is a derivative of citric acid; that is, the salt (chemistry), salts, esters, and the polyatomic ion, polyatomic anion found in solutions and salts of citric acid. An example of the former, a salt is trisodium citrate; an ester is triethyl citrate. When citrate anion, trianion is part of a salt, the formula of the citrate trianion is written as or . Natural occurrence and industrial production Citric acid occurs in a variety of fruits and vegetables, most notably Citrus, citrus fruits. Lemons and Lime ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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PH meter
A pH meter is a scientific instrument that measures the hydrogen-ion Thermodynamic activity, activity in Aqueous solution, water-based solutions, indicating its acidity or alkalinity expressed as pH. The pH meter measures the difference in electrical potential between a pH electrode and a reference electrode, and so the pH meter is sometimes referred to as a "potentiometric pH meter". The difference in electrical potential relates to the acidity or pH of the solution. Testing of pH via pH meters (pH-metry) is used in many applications ranging from Experimentation, laboratory experimentation to quality control. Applications The rate and outcome of chemical reactions taking place in water often depends on the acidity of the water, and it is therefore useful to know the acidity of the water, typically measured by means of a pH meter. Knowledge of pH is useful or critical in many situations, including chemical laboratory analyses. pH meters are used for soil measurements in agric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Fermentation (biochemistry)
Fermentation is a type of anaerobic metabolism which harnesses the redox potential of the reactants to make adenosine triphosphate (ATP) and organic end products. Organic molecules, such as glucose or other sugars, are catabolized and reduced by donating their electrons to other organic molecules (cofactors, coenzymes, etc.). Fermentation is important in several areas of human society. Humans have used fermentation in the production and preservation of food for 13,000 years. It has been associated with health benefits, unique flavor profiles, and making products have better texture. Humans and their livestock also benefit from fermentation from the microbes in the gut that release end products that are subsequently used by the host for energy. Perhaps the most commonly known use for fermentation is at an industrial level to produce commodity chemicals, such as ethanol and lactate. Ethanol is used in a variety of alcoholic beverages (beers, wine, and spirits) while lactate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Phosphate Buffered Saline
Phosphate-buffered saline (PBS) is a buffer solution (pH ~ 7.4) commonly used in biological research. It is a water-based salt solution containing disodium hydrogen phosphate, sodium chloride and, in some formulations, potassium chloride and potassium dihydrogen phosphate. The buffer helps to maintain a constant pH. The osmolarity and ion concentrations of the solutions are isotonic, meaning they match those of the human body. Applications PBS has many uses because it is isotonic and non-toxic to most cells. These uses include substance dilution and cell container rinsing. PBS with EDTA is also used to disengage attached and clumped cells. Divalent metals such as zinc, however, cannot be added as this will result in precipitation. For these types of applications, Good's buffers are recommended. PBS has been shown to be an acceptable alternative to viral transport medium regarding transport and storage of RNA viruses, such as SARS-CoV-2. Preparation There are many different way ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Denaturation (biochemistry)
In biochemistry, denaturation is a process in which proteins or nucleic acids lose folded structure present in their native state due to various factors, including application of some external stress or compound, such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation, radiation, or heat. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death. Protein denaturation is also a consequence of cell death. Denatured proteins can exhibit a wide range of characteristics, from conformational change and loss of solubility or dissociation of cofactors to aggregation due to the exposure of hydrophobic groups. The loss of solubility as a result of denaturation is called ''coagulation''. Denatured proteins, e.g., metalloenzymes, lose their 3D structure or metal cofactor, and therefore, cannot function. Proper protein folding is key to whether a globular or memb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Alkalosis
Alkalosis is the result of a process reducing hydrogen ion concentration of arterial blood plasma (alkalemia). In contrast to acidemia (serum pH 7.35 or lower), alkalemia occurs when the serum pH is higher than normal (7.45 or higher). Alkalosis is usually divided into the categories of respiratory alkalosis and metabolic alkalosis or a combined respiratory/metabolic alkalosis. Signs and symptoms Metabolic alkalosis is usually accompanied by low blood potassium concentration, causing, e.g., muscular weakness, muscle pain, and muscle cramps (from disturbed function of the skeletal muscles), and muscle spasms (from disturbed function of smooth muscles). It may also cause low blood calcium concentration. As the blood pH increases, blood transport proteins, such as albumin, become more ionized into anions. This causes the free calcium present in blood to bind more strongly with albumin. If severe, it may cause tetany. Causes Respiratory alkalosis is caused by hyperventilati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |