Oxytocinergic
The oxytocin receptor, also known as OXTR, is a protein which functions as receptor (biochemistry), receptor for the hormone and neurotransmitter oxytocin. In humans, the oxytocin receptor is encoded by the ''OXTR'' gene which has been localized to human chromosome 3, chromosome 3p25. Function and location The OXTR protein belongs to the G protein-coupled receptor, G-protein coupled receptor family, specifically Gq alpha subunit, Gq, and acts as a receptor for oxytocin. Its activity is mediated by G proteins that activate several different second messenger systems. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. OXTR is also associated with the central nervous system. The gene is believed to play a major role in social, cog ...
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