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Oroxindin
Oroxindin is a flavone, a type of phenolic chemical compound. It is a wogonoside, more accurately a wogonin glucuronide isolated from ''Oroxylum indicum'' (Bignoniaceae), ''Bacopa monnieri'' (Plantaginaceae) and ''Holmskioldia sanguinea'' (Chinese hat plant, Verbenaceae). References External links Oroxindin at nextbio.com
Flavone glycosides Flavonoid glucuronides Glucuronide esters {{Aromatic-stub ...
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Wogonoside
Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in '' Scutellaria baicalensis''. The glycosides of wogonin are known as wogonosides. For example, oroxindin is a wogonin glucuronide isolated from ''Oroxylum indicum''. It is one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement. Wogonin has been found in one study to have anxiolytic properties in mice at doses of 7.5 to 30 mg/kg, without exhibiting the sedative and muscle-relaxing properties of benzodiazepines. Preliminary '' in vitro'' studies have shown pharmacological effects that indicate wogonin may have anti-tumor properties. Wogonin has also been found to possess anticonvulsant Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of b ... effects. It acts as a posit ...
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Flavone
Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products. Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone. Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bon .... References {{Flavones ...
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Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond. The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucuronides, is a method that animals use to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; bloo ...s. Enzymes that cleave the glycosidic bond of a glucuronide are called glucuronidases. Examples * Miquelianin ( Quercetin 3-O-glucur ...
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Oroxylum Indicum
''Oroxylum indicum'' is a species of flowering plant belonging to the monotypic genus ''Oroxylum'' and the family Bignoniaceae, and is commonly called Indian trumpet tree, oroxylum, Indian trumpet flower, broken bones, Indian caper, scythe tree or tree of Damocles. It can reach a height of . Various segments of the tree are used in traditional medicine, where it is known as Shyonaka or Sona Patha. Description The large leaf stalks wither and fall off the tree and collect near the base of the trunk, appearing to look like a pile of broken limb bones. The pinnate leaves are approximately in length and comparably wide, borne on petioles or stalks up to in length, making this the largest of all dicot tree leaves, which are quadripinnate (leaflets display four orders of branching). The tree is a night-bloomer and flowers are adapted to natural pollination by bats. They form enormous seed pods – the fruits – are up to long that hang down from bare branches, resembling ...
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Bacopa Monnieri
''Bacopa monnieri'' is a perennial, creeping herb native to the wetlands of southern and Eastern India, Australia, Europe, Africa, Asia, and North and South America. It is known by the common names water hyssop, waterhyssop, brahmi, thyme-leafed gratiola, herb of grace, and Indian pennywort. ''Bacopa monnieri'' is used in Ayurveda. In 2019, the US Food and Drug Administration (FDA) warned manufacturers of dietary supplement products containing ''Bacopa monnieri'' against making illegal and unproven claims that the herb can treat various diseases. Description ''Bacopa monnieri'' is a non-aromatic herb. The leaves of this plant are succulent, oblong, and thick. Leaves are oblanceolate and are arranged oppositely on the stem. The flowers are small, actinomorphic and white, with four to five petals. It can even grow in slightly brackish conditions. Propagation is often achieved through cuttings. Ecology ''Bacopa monnieri'' is one of the most widespread ''Bacopa'' species. It ...
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Holmskioldia Sanguinea
''Holmskioldia'' is a genus of flowering plants in the mint family, Lamiaceae. It is native to the Himalayas (India, Pakistan, Nepal, Bhutan, Bangladesh, Myanmar) but widely cultivated as an ornamental and naturalized in many places (Southeast Asia, New Caledonia, Hawaii, Mexico, West Indies, Venezuela, etc.) It contains only one known species, ''Holmskioldia sanguinea'', commonly called the Chinese hat plant, cup-and-saucer-plant or mandarin's hat. The genus name commemorates Johan Theodor Holmskiold (1731-1793), a Danish botanist who wrote ''Beata ruris otia fungis Danicis'', published in two volumes in 1790 and 179 Species formerly included The following species have been moved to genus '' Karomia'': * '' Holmskioldia gigas'' Faden = '' Karomia gigas'' (Faden) Verdc. * '' Holmskioldia speciosa'' Hutch. & Corbishley = '' Karomia speciosa'' (Hutch. & Corbishley) R.Fern. – Southern Chinese hats, wild parasol flower * '' Holmskioldia tettensis'' (Klotzsch) Vatke = '' Karomia te ...
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Flavone Glycosides
Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products. Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone. Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bon .... References {{Flavones ...
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Flavonoid Glucuronides
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids *isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4-benzopyrone) structure *neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to describe non- ...
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