|
Ormosil
Ormosil is a shorthand phrase for ''organically modified silica'' or ''organically modified silicate''. In general, ormosils are produced by adding silane to silica-derived gel during the sol-gel process. They are engineered materials that show great promise in a wide range of applications such as: * alternative to viral vectors for gene delivery, with higher transient transfection efficiencies * suspension media and substrates for next generation solar cells (quantum dots)and photocatalytic oxidation of water * matrix material for UV-protection coating * matrix material for laser dye-doped organic-inorganic solid state dye lasers This technology has been demonstrated as a nonviral vector to successfully deliver DNA loads to specifically targeted cells in living animals. Confirmation of results demonstrated that new DNA was working and expressed genes in the animal. Sono-Ormosil Sono-Ormosils are organically modified silicates, which were prepared by using high-performance u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solid State Dye Lasers
Solid-state dye lasers (SSDL) were introduced in 1967 by Soffer and McFarland. In these solid-state lasers, the gain medium is a laser dye-doped organic matrix such as poly(methyl methacrylate) (PMMA), rather than a liquid solution of the dye. An example is rhodamine 6G-doped PMMA. These lasers are also referred to as solid-state organic lasers and solid-state dye-doped polymer lasers. Organic gain media In the 1990s, new forms of improved PMMA, such as modified PMMA, with high optical quality characteristics were introduced. Gain media research for SSDL has been rather active in the 21st century, and various new dye-doped solid-state organic matrices have been discovered. Notable among these new gain media are organic-inorganic dye-doped polymer-nanoparticle composites. An additional form of organic-inorganic dye-doped solid-state laser gain media are the ORMOSILs. High performance solid-state dye laser oscillators This improved gain medium was central to the demonstra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Laser
Organic lasers use an organic (carbon based) material as the gain medium. The first organic laser was the liquid dye laser. These lasers use laser dye solutions as their gain media. Organic lasers are inherently tunable and when configured as optimized multiple-prism grating laser oscillators can yield efficient single-transverse mode, and single-longitudinal-mode, emission with laser linewidths as narrow as 350 MHz (approximately 0.0004 nm at a wavelength of 590 nm), in the high-power pulsed regime. Solid-state dye lasers Solid-state dye lasers are organic tunable lasers that use a variety of organic gain media, such as laser dye-doped polymers (DDP), laser dye-doped ormosil (DDO), and laser dye-doped polymer-nanoparticle (DDPN) matrices. DDO and DDPN gain media are subsets of a larger class of organic-inorganic hybrid materials used as laser matrices. Organic semiconductor laser Other types of solid-state organic lasers include the organic semicondu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Photonics
Organic photonics includes the generation, emission, transmission, modulation, signal processing, switching, amplification, and detection/sensing of light, using organic optical materials. Fields within organic photonics include the liquid organic dye laser and solid-state organic dye lasers. Materials used in solid-state dye lasers include: * laser dye-doped PMMA * laser dye-doped ormosil * laser dye-doped polymer-nanoparticle matrices * laser dye-doped bio-based gain media Organic-inorganic nanoparticle gain media are nanocomposites developed for solid-state dye lasers and can also be utilized in biosensors, bio analytics, and nonlinear organic photonics applications. An additional class of organic materials used in the generation of laser light include organic semiconductors.C. Karnutsch, ''Low Threshold Organic Thin Film Laser Devices'' (Cuvillier, Göttingen, 2007). Conjugated polymers are widely used as optically-pumped organic semiconductors. See also * Conjugated ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silica
Silicon dioxide, also known as silica, is an oxide of silicon with the chemical formula , most commonly found in nature as quartz and in various living organisms. In many parts of the world, silica is the major constituent of sand. Silica is one of the most complex and most abundant families of materials, existing as a compound of several minerals and as a synthetic product. Notable examples include fused quartz, fumed silica, silica gel, opal and aerogels. It is used in structural materials, microelectronics (as an electrical insulator), and as components in the food and pharmaceutical industries. Structure In the majority of silicates, the silicon atom shows tetrahedral coordination, with four oxygen atoms surrounding a central Si atomsee 3-D Unit Cell. Thus, SiO2 forms 3-dimensional network solids in which each silicon atom is covalently bonded in a tetrahedral manner to 4 oxygen atoms. In contrast, CO2 is a linear molecule. The starkly different structures of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silicate
In chemistry, a silicate is any member of a family of polyatomic anions consisting of silicon and oxygen, usually with the general formula , where . The family includes orthosilicate (), metasilicate (), and pyrosilicate (, ). The name is also used for any salt of such anions, such as sodium metasilicate; or any ester containing the corresponding chemical group, such as tetramethyl orthosilicate. The name "silicate" is sometimes extended to any anions containing silicon, even if they do not fit the general formula or contain other atoms besides oxygen; such as hexafluorosilicate .Most commonly, silicates are encountered as silicate minerals. For diverse manufacturing, technological, and artistic needs, silicates are versatile materials, both natural (such as granite, gravel, and garnet) and artificial (such as Portland cement, ceramics, glass, and waterglass). Structural principles In all silicates, silicon atom occupies the center of an idealized tetrahedro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanoparticles
A nanoparticle or ultrafine particle is usually defined as a particle of matter that is between 1 and 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead. Nanoparticles are usually distinguished from microparticles (1-1000 µm), "fine particles" (sized between 100 and 2500 nm), and "coarse particles" (ranging from 2500 to 10,000 nm), because their smaller size drives very different physical or chemical properties, like colloidal properties and ultrafast optical effects or electric properties. Being more subject to the brownian motion, they usually do not sediment, like colloidal particles that conversely are usually understood to range from 1 to 1000 nm. Being much smaller than the wavelengths of visible light (400-700 nm), nan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Vector
Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism ('' in vivo'') or in cell culture (''in vitro''). Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect. Delivery of genes or other genetic material by a vector is termed transduction and the infected cells are described as transduced. Molecular biologists first harnessed this machinery in the 1970s. Paul Berg used a modified SV40 virus containing DNA from the bacteriophage λ to infect monkey kidney cells maintained in culture. In addition to their use in molecular biology research, viral vectors are used for gene therapy and the development of vaccines. Key properties of a viral vector VIRAL VECTORS are tailored to their specific applications but generally share a few key properties. *''Safety'': Although viral vectors are occasionally created from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transfection
Transfection is the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells. It may also refer to other methods and cell types, although other terms are often preferred: " transformation" is typically used to describe non-viral DNA transfer in bacteria and non-animal eukaryotic cells, including plant cells. In animal cells, transfection is the preferred term as transformation is also used to refer to progression to a cancerous state (carcinogenesis) in these cells. Transduction is often used to describe virus-mediated gene transfer into eukaryotic cells. The word ''transfection'' is a portmanteau of ''trans-'' and ''infection''. Genetic material (such as supercoiled plasmid DNA or siRNA constructs), may be transfected. Transfection of animal cells typically involves opening transient pores or "holes" in the cell membrane to allow the uptake of material. Transfection can be carried out using calcium phosphate (i.e. tricalcium phosphate), by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solar Cell
A solar cell, or photovoltaic cell, is an electronic device that converts the energy of light directly into electricity by the photovoltaic effect, which is a physical and chemical phenomenon.Solar Cells chemistryexplained.com It is a form of photoelectric cell, defined as a device whose electrical characteristics, such as current, voltage, or , vary when exposed to light. Individual solar cell devices are often the electrical building blocks of [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laser Dye
Laser dyes are dyes used as laser medium in a dye laser. Laser dyes include the coumarins and the rhodamines. Coumarin dyes emit in the green region of the spectrum, whereas rhodamine dyes are used for emission in the yellow-red. The color emitted by the laser dyes depend upon the surrounding medium i.e.the medium in which they are dissolved. However, there are dozens of laser dyes that can be used to span continuously the emission spectrum from the near ultraviolet to the near infrared.F. J. Duarte, ''Tunable Laser Optics'' (Elsevier-Academic, New York, 2003) Appendix of Laser Dyes (includes more than 50 laser dyes) Laser dyes are also used to dope solid-state matrices, such as poly(methyl methacrylate) (PMMA), and ORMOSILs, to provide gain media for solid state dye lasers. Partial list of laser dyes *Coumarins (in various nomenclatures such as Coumarin 480, 490, 504, 521, 504T, 521T) *Fluorescein * polyphenyl ("polyphenyl 1") S. C. Guggenheimer, A. B. Petersen"High ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
