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Orellanine
Orellanine or orellanin is a mycotoxin found in a group of mushrooms known as the Orellani of the family Cortinariaceae. Structurally, it is a bipyridine N-oxide compound somewhat related to the herbicide diquat. History Orellanine first came to people's attention in 1952 when a mass poisoning of 102 people in Konin, Poland, resulted in 11 deaths. Orellanine comes from a class of mushrooms that fall under the genus ''Cortinarius,'' and has been found in the species '' C. orellanus'', '' rubellus'', ''henrici'', '' rainerensis'' and '' bruneofulvus''. Poisonings related to these mushrooms have occurred predominately in Europe where mushroom foraging was common, though cases of orellanine poisoning have been reported in North America and Australia as well. There are several reported cases of people ingesting orellanine-containing mushrooms after mistaking them for edible or hallucinogenic mushrooms. Orellanine was first isolated in 1962, when Stanisław Grzymala extracted and iso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinarius Rainierensis
The Orellani are a group of seven related species in the genus ''Cortinarius'' that have been classified as a section of the subgenus ''Leprocybe'' or a subgenus in their own right. They are among world's most poisonous mushrooms as they contain the highly toxic compound orellanine. The best-known species are the deadly webcap (''Cortinarius rubellus'', formerly also known as ''C. speciosissimus'' or ''C. orellanoides'') and the fool's webcap, '' C. orellanus''. The mushrooms' characteristics are quite common, making them difficult to identify, which often leads to fatal poisonings. Young examples of the species often have a veil between the cap of the mushroom and the stem. This veil looks like a cobweb, hence the name. The veil however partially or completely disappears in older specimens. Some other characteristics for each of the mushrooms are given below. Descriptions Deadly webcap ''(Cortinarius rubellus)'' ''Spore color'': Rusty brown to orange ''Cap'': 3–7 cm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinariaceae
The Cortinariaceae are a large family of gilled mushrooms found worldwide, containing over 2100 species. The family takes its name from its largest genus, the varied species of the genus ''Cortinarius''. Many genera formerly in the Cortinariaceae have been placed in various other families, including Hymenogastraceae, Inocybaceae and Bolbitiaceae. The deadly toxin orellanine has been found in at least 34 Cortinariaceae. Taxonomic details Cortinariaceae is a family of mushrooms within the Order Agaricales. The spore producing hymenium is located on the gills. The pileipellis is a cutis. The spores are brown in deposit and, in most genera in this family, the spores are ornamented. Differences in genera ''Cortinarius'' are mushrooms with warted spores, which are rusty-brown in deposit. Mushrooms in this genus have a partial veil which is a cortina. These mushrooms are terrestrial and mycorrhizal, and can range from small to large and fleshy. Edibility Despite the vast number of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinarius Henrici
''Cortinarius'' is a globally distributed genus of mushrooms in the family Cortinariaceae. It is suspected to be the largest genus of agarics, containing over 2,000 widespread species. A common feature among all species in the genus ''Cortinarius'' is that young specimens have a cortina (veil) between the cap and the stem, hence the name, meaning ''curtained''. Most of the fibres of the cortina are ephemeral and will leave no trace once gone, except for limited remnants on the stem or cap edge in some species. All have a rusty brown spore print. The common names cortinar and webcap refer to members of the genus. Due to dangerous toxicity of several species (such as ''Cortinarius orellanus'') and the fact that it is difficult to distinguish between various species of the genus, non-expert consumption of mushrooms from the genus is discouraged. Distinguishing features The veil protects the gill (mushroom), gills in younger specimens and usually disappears leaving little to no trace ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinarius Bruneofulvus
''Cortinarius'' is a globally distributed genus of mushrooms in the family Cortinariaceae. It is suspected to be the largest genus of agarics, containing over 2,000 widespread species. A common feature among all species in the genus ''Cortinarius'' is that young specimens have a cortina (veil) between the cap and the stem, hence the name, meaning ''curtained''. Most of the fibres of the cortina are ephemeral and will leave no trace once gone, except for limited remnants on the stem or cap edge in some species. All have a rusty brown spore print. The common names cortinar and webcap refer to members of the genus. Due to dangerous toxicity of several species (such as '' Cortinarius orellanus'') and the fact that it is difficult to distinguish between various species of the genus, non-expert consumption of mushrooms from the genus is discouraged. Distinguishing features The veil protects the gills in younger specimens and usually disappears leaving little to no trace of itself ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinarius
''Cortinarius'' is a globally distributed genus of mushrooms in the family Cortinariaceae. It is suspected to be the largest genus of agarics, containing over 2,000 widespread species. A common feature among all species in the genus ''Cortinarius'' is that young specimens have a cortina (veil) between the cap and the stem, hence the name, meaning ''curtained''. Most of the fibres of the cortina are ephemeral and will leave no trace once gone, except for limited remnants on the stem or cap edge in some species. All have a rusty brown spore print. The common names cortinar and webcap refer to members of the genus. Due to dangerous toxicity of several species (such as '' Cortinarius orellanus'') and the fact that it is difficult to distinguish between various species of the genus, non-expert consumption of mushrooms from the genus is discouraged. Distinguishing features The veil protects the gills in younger specimens and usually disappears leaving little to no trace of itself as t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinarius Orellanus
''Cortinarius orellanus'', commonly known as the fool's webcap or fools webcap, is a species of deadly fungus in the family Cortinariaceae native to Europe. Within the genus it belongs to a group known as the Orellani, all of which are highly toxic—eating them results in kidney failure, which is often irreversible. The mushroom is generally tan to brown all over. Taxonomy ''Cortinarius orellanus'' was first described by Swedish mycologist Elias Magnus Fries in his 1838 book ''Epicrisis Systematis Mycologici seu Synopsis Hymenomycetum''. It is one of seven highly toxic species that make up the orellani, a subgenus within genus ''Cortinarius''. Description ''Cortinarius orellanus'' has a concave cap of diameter, though rare specimens reach across. The cap flattens with age. In colour, it is an orange-brown, and is covered in fine, fibrous scales but become smooth with age. The cap surface turns black with potassium hydroxide. The thick gills are light ochre-coloured, chang ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycotoxin
A mycotoxin (from the Greek μύκης , "fungus" and τοξίνη , "toxin") is a toxic secondary metabolite produced by organisms of kingdom Fungi and is capable of causing disease and death in both humans and other animals. The term 'mycotoxin' is usually reserved for the toxic chemical products produced by fungi that readily colonize crops. Examples of mycotoxins causing human and animal illness include aflatoxin, citrinin, fumonisins, ochratoxin A, patulin, trichothecenes, zearalenone, and ergot alkaloids such as ergotamine. One mold species may produce many different mycotoxins, and several species may produce the same mycotoxin. Production Most fungi are aerobic (use oxygen) and are found almost everywhere in extremely small quantities due to the diminute size of their spores. They consume organic matter wherever humidity and temperature are sufficient. Where conditions are right, fungi proliferate into colonies and mycotoxin levels become high. The reason for the product ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortinarius Rubellus
''Cortinarius rubellus'', commonly known as the deadly webcap, is a species of fungus in the family Cortinariaceae, native to high-latitude temperate to subalpine forests of Eurasia and North America. Within the genus it belongs to a group known as the Orellani, all of which are highly toxic. Eating them results in kidney failure, which is often irreversible. The mushroom is generally tan to brown all over, with a conical to convex cap in diameter, adnate gills and a tall stipe. Taxonomy British naturalist Mordecai Cubitt Cooke described ''Cortinarius rubellus'' in 1887 from material collected by a Dr. Carlyle at Orton Moss near Carlisle, Cumbria. The name was rarely used before 1980, however. ''Cortinarius orellanoides'' was described by Henry in 1937 from mushrooms growing under bracken (''Pteridium aquilinum'') and beech in France, while Robert Kühner and Henri Romagnesi described ''C. speciosissimus'' (initially ''C. speciosus'', but that name had already been given to an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Racemic Mixture
In chemistry, a racemic mixture, or racemate (), is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds are produced industrially as racemates. History The first known racemic mixture was racemic acid, which Louis Pasteur found to be a mixture of the two enantiomeric isomers of tartaric acid. He manually separated the crystals of a mixture by hand, starting from an aqueous solution of the sodium ammonium salt of racemate tartaric acid. Pasteur benefited from the fact that ammonium tartrate salt that gives enantiomeric crystals with distinct crystal forms (at 77 °F). Reasoning from the macroscopic scale down to the molecular, he reckoned that the molecules had to have non-superimposable mirror images. A sample with only a single enantiomer is an ''enantiomerically pure'' or ''enantiopure'' compound. Etymology From racemic acid found in grapes; from Latin ''racemus'', m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamma-glutamyltransferase
Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT, gamma-glutamyl transpeptidase; ) is a transferase (a type of enzyme) that catalyzes the transfer of gamma- glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione as well as drug and xenobiotic detoxification. Other lines of evidence indicate that GGT can also exert a pro-oxidant role, with regulatory effects at various levels in cellular signal transduction and cellular pathophysiology. This transferase is found in many tissues, the most notable one being the liver, and has significance in medicine as a diagnostic marker. Nomenclature The name γ-glutamyltransferase is preferred by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. The Expert Panel on Enzymes of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
