|
Notch Family Of Receptors
Notch may refer to: * Notch (engineering), an indentation or slit in a material * Nock (arrow), notch in the rearmost end of an arrow * Markus Persson (born 1979), a Swedish video game designer known by his online alias "Notch" * Notch (musician) (born 1973), a hip hop, R&B, reggae, dancehall and reggaeton artist * ''NOTCH'' (magazine), an Indian entertainment and lifestyle magazine * Notch, Missouri, a community in the United States * Notch signalling pathway, a cell signalling system present in most multicellular organisms * Notch proteins, a family of transmembrane proteins * Notch filter, a band-stop filter with a narrow stopband * Notch test, also known as Charpy impact test * Lion Notch, a male lion featured in the nature documentary series ''Big Cat Diary'' * Notch display, an electronic screen with a cutout in it * A type of col in geomorphology See also * * * Top Notch (other) * Niche (other) * Nutch Apache Nutch is a highly extensible and scalable ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Notch (engineering)
In mechanical engineering and materials science, a notch refers to a V-shaped, U-shaped, or semi-circular defect deliberately introduced into a planar material. In structural components, a notch causes a stress concentration which can result in the initiation and growth of fatigue cracks. Notches are used in materials characterization to determine fracture mechanics related properties such as fracture toughness and rates of fatigue crack growth. Notches are commonly used in material impact tests where a morphological crack of a controlled origin is necessary to achieve standardized characterization of fracture resistance of the material. The most common is the Charpy impact test, which uses a pendulum hammer (striker) to strike a horizontal notched specimen. The height of its subsequent swing-through is used to determine the energy absorbed during fracture. The Izod impact strength test uses a circular notched vertical specimen in a cantilever configuration. Charpy testing is c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Nock (arrow)
An arrow is a fin-stabilized projectile launched by a bow. A typical arrow usually consists of a long, stiff, straight shaft with a weighty (and usually sharp and pointed) arrowhead attached to the front end, multiple fin-like stabilizers called fletchings mounted near the rear, and a slot at the rear end called a nock for engaging the bowstring. A container or bag carrying additional arrows for convenient reloading is called a quiver. The use of bows and arrows by humans predates recorded history and is common to most cultures. A craftsman who makes arrows is a fletcher, and one who makes arrowheads is an arrowsmith.Paterson ''Encyclopaedia of Archery'' p. 56 History The oldest evidence of likely arrowheads, dating to years ago, were found in Sibudu Cave, current South Africa.Backwell L, d'Errico F, Wadley L.(2008). Middle Stone Age bone tools from the Howiesons Poort layers, Sibudu Cave, South Africa. Journal of Archaeological Science, 35:1566–1580. Backwell L, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Markus Persson
Markus Alexej Persson ( , ; born 1 June 1979), known by the pseudonym Notch, is a Swedish video game programmer and Video game designer, designer. He is the creator of ''Minecraft'', which is the List of best-selling video games, best-selling video game in history. He founded the video game development company Mojang Studios in 2009. Persson began developing video games at an early age. His commercial success began after he published an early version of ''Minecraft'' in 2009. Prior to the game's official retail release in 2011, it had sold over ten million copies. After this point Persson stood down as the lead designer and transferred his creative authority to Jens Bergensten. In September 2014 Persson announced on his personal website that he had concluded he "[didn't have the connection to his fans he thought he had]", that he had "become a symbol", and that he did not wish to be responsible for Mojang's increasingly large operation. He left Mojang in November of that year, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Notch (musician)
Norman Howell (born May 11, 1975), better known as Notch, is an American R&B, reggae, dancehall, and reggaeton artist. He was the former lead vocalist and one of the creative forces behind the hip-hop/reggae group Born Jamericans. He is known for his 2001 chart topper, "Nuttin Nuh Go So." He has featured on albums such as ''Mas Flow 2'', '' Mas Flow 2.5'', '' Chosen Few II: El Documental'', '' Barrio Fino'', and '' The Cosmic Game''. His first solo album, ''Raised by the People'', was released in May 2007. Biography Early life Howell was born in Hartford, Connecticut. His mother is of African-American, Native American, and Portuguese descent, however his brothers and sisters, from the same mother but different father, are of Puerto Rican and African-American descent. His father was born in Jamaica and is of Afro-Cuban and French descent. Howell's parents separated when he was still an infant. He spent his early years with his mother, living in Hartford, Connecticut. Howe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
NOTCH (magazine)
''NOTCH'' is an Indian entertainment and lifestyle online magazine. It is part of privately held Pradeep Dadha Group of Companies, with Pradeep Dadha as chairman. ''NOTCHs corporate office is located in Chennai, India. History The online magazine was launched in September 2012, and the cover of the first issue featured Bollywood actress Kareena Kapoor. In addition to stories, the magazine includes multimedia content. Target audience ''NOTCH'' is geared to Indian consumers as well as non-resident Indians (NRI) living outside of India India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since .... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Notch, Missouri
Notch is an unincorporated community in Stone County, in the U.S. state of Missouri. Notch is located just north of Silver Dollar City on Missouri Route 76 Route 76 is a highway in the west half of southern Missouri running between U.S. Route 60 and U.S. Route 63 at Willow Springs and the Oklahoma state line near Tiff City where it continues as a county road. It bypasses Branson on the Ozark .... History A post office called Notch was established in 1895, and remained in operation until 1934. The community was named for "notches" (i.e. blazes) on the road through town. A variant name was "The Forks". References Unincorporated communities in Stone County, Missouri Unincorporated communities in Missouri {{StoneCountyMO-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Notch Signalling Pathway
The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region. Notch signaling promotes proliferative signaling during neurogenesis, and its activity is inhibited by Numb to promote neural differentiation. It plays a major role in the regulation of embryonic development. Notch signaling is dysregulated in many cancers, and faulty notch signaling is implicated in many diseases, including T-cell acute lymphoblastic leukemia ( T-ALL), cerebral autosomal-dominant arteriopathy with sub-cortical infarcts an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Notch Proteins
__NOTOC__ __FORCETOC__ Notch proteins are a family of type 1 transmembrane proteins that form a core component of the Notch signaling pathway, which is highly conserved in animals. The Notch extracellular domain mediates interactions with DSL family ligands, allowing it to participate in juxtacrine signaling. The Notch intracellular domain acts as a transcriptional activator when in complex with CSL family transcription factors. Members of this type 1 transmembrane protein family share several core structures, including an extracellular domain consisting of multiple epidermal growth factor (EGF)-like repeats and an intracellular domain transcriptional activation domain (TAD). Notch family members operate in a variety of different tissues and play a role in a variety of developmental processes by controlling cell fate decisions. Much of what is known about Notch function comes from studies done in ''Caenorhabditis elegans'' (''C.elegans'') and ''Drosophila melanogaster.'' Human hom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Band-stop Filter
In signal processing, a band-stop filter or band-rejection filter is a filter that passes most frequencies unaltered, but attenuates those in a specific range to very low levels. It is the inverse of a ''band-pass filter''. A notch filter is a band-stop filter with a narrow stopband (high Q factor). Narrow notch filters (optical) are used in Raman spectroscopy, live sound reproduction (public address systems, or PA systems) and in instrument amplifiers (especially amplifiers or preamplifiers for acoustic instruments such as acoustic guitar, mandolin, bass instrument amplifier, etc.) to reduce or prevent audio feedback, while having little noticeable effect on the rest of the frequency spectrum ( electronic or software filters). Other names include "band limit filter", "T-notch filter", "band-elimination filter", and "band-reject filter". Typically, the width of the stopband is 1 to 2 decades (that is, the highest frequency attenuated is 10 to 100 times the lowest frequency ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Charpy Impact Test
In materials science, the Charpy impact test, also known as the Charpy V-notch test, is a standardized high strain rate test which determines the amount of energy absorbed by a material during fracture. Absorbed energy is a measure of the material's notch (engineering), notch toughness. It is widely used in industry, since it is easy to prepare and conduct and results can be obtained quickly and cheaply. A disadvantage is that some results are only comparative. The test was pivotal in understanding the fracture problems of ships during World War II. The test was developed around 1900 by S. B. Russell (1898, American) and Georges Charpy (1901, French). The test became known as the Charpy test in the early 1900s due to the technical contributions and standardization efforts by Charpy. History In 1896, S. B. Russell introduced the idea of ''residual fracture energy'' and devised a pendulum fracture test. Russell's initial tests measured un-notched samples. In 1897, Frémont intro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Big Cat Diary
''Big Cat Diary'', also known as ''Big Cat Week'' or ''Big Cat Live'', is a long-running nature documentary series on BBC television which followed the lives of African big cats in Kenya's Maasai Mara. The first series, broadcast on BBC One in 1996, was developed and jointly produced by Keith Scholey, who would go on to become Head of the BBC's Natural History Unit. Eight series have followed, most recently ''Big Cat Live'', a live broadcast from the Mara in 2008. The original presenters, Jonathan Scott and Simon King, were joined by Saba Douglas-Hamilton from 2002 onwards. Kate Silverton and Jackson Looseyia were added to the presenting team for ''Big Cat Live''. Merchandise Currently available on Region 2 DVD are the 2004, 2005 and 2006 series of ''Big Cat Week'' (packaged as series 1 to 3, with series 1 and 2 being packaged together), the 2007 series of ''Big Cat Diary'' (packaged as series 4 of ''Big Cat Week'') and highlights from ''Big Cat Live'' (packaged as ''Big ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Notch Display
A smartphone is a mobile phone with advanced computing capabilities. It typically has a touchscreen interface, allowing users to access a wide range of applications and services, such as web browsing, email, and social media, as well as multimedia playback and streaming. Smartphones have built-in cameras, GPS navigation, and support for various communication methods, including voice calls, text messaging, and internet-based messaging apps. Smartphones are distinguished from older-design feature phones by their more advanced hardware capabilities and extensive mobile operating systems, access to the internet, business applications, mobile payments, and multimedia functionality, including music, video, gaming, radio, and television. Smartphones typically feature metal–oxide–semiconductor (MOS) integrated circuit (IC) chips, various sensors, and support for multiple wireless communication protocols. Examples of smartphone sensors include accelerometers, barometers, gyroscopes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
