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Myalgic Encephalitis
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. People with ME/CFS experience profound fatigue that does not go away with rest, as well as sleep issues and problems with memory or concentration. The hallmark symptom is post-exertional malaise (PEM), a worsening of the illness which can start immediately or hours to days after even minor physical or mental activity. This "crash" can last from hours or days to several months. Further common symptoms include dizziness or faintness when upright and pain. The cause of the disease is unknown. ME/CFS often starts after an infection, such as mononucleosis. It can run in families, but no genes that contribute to ME/CFS have been confirmed. ME/CFS is associated with changes in the nervous and immune systems, as well as in energy production. Diagnosis is based on distinctive symptoms, and a differential diagnosis, because no diagnostic test such as a blood test or imaging is available. Sy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fatigue
Fatigue is a state of tiredness (which is not sleepiness), exhaustion or loss of energy. It is a signs and symptoms, symptom of any of various diseases; it is not a disease in itself. Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases, and post-infectious-disease states. However, fatigue is complex and in up to a third of primary care cases no medical or psychiatric diagnosis is found. Fatigue (in the general usage sense of normal tiredness) often follows prolonged physical or mental activity. Physical fatigue results from muscle fatigue brought about by intense physical activity. Mental fatigue results from prolonged periods of Cognition, cognitive activity which impairs cognitive ability, can manifest as sleepiness, lethargy, or directed attention fatigue, and can also impair physical performance. Definition Fatigue in a medica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Geneva, Switzerland, and has 6 regional offices and 150 field offices worldwide. Only sovereign states are eligible to join, and it is the largest intergovernmental health organization at the international level. The WHO's purpose is to achieve the highest possible level of health for all the world's people, defining health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." The main functions of the World Health Organization include promoting the control of epidemic and endemic diseases; providing and improving the teaching and training in public health, the medical treatment of disease, and related matters; and promoting the establishment of international standards for biologic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurological Disorder
Neurological disorders represent a complex array of medical conditions that fundamentally disrupt the functioning of the nervous system. These disorders affect the brain, spinal cord, and nerve networks, presenting unique diagnosis, treatment, and patient care challenges. At their core, they represent disruptions to the intricate communication systems within the nervous system, stemming from genetic predispositions, environmental factors, infections, structural abnormalities, or degenerative processes. The impact of neurological disorders is profound and far-reaching. Conditions like epilepsy create recurring seizures through abnormal electrical brain activity, while multiple sclerosis damages the protective myelin covering of nerve fibers, interrupting communication between the brain and body. Parkinson's disease progressively affects movement through the loss of dopamine-producing nerve cells, and strokes can cause immediate and potentially permanent neurological damage by inter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Controversies Related To ME/CFS
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an illness with a long history of controversy. Some professionals within the medical community do not recognize ME/CFS as a genuine condition, nor is there agreement on its prevalence. There has been much disagreement over the pathophysiology of chronic fatigue syndrome, how it should be diagnosed, and how to treat it. The diagnosis is controversial, and its etiology is still not fully understood. Alternative names to describe the condition(s) have been used over time throughout the world. Patient groups have criticized the name "chronic fatigue syndrome", saying that it trivializes the illness. Neglect and lack of awareness ME/CFS suffers from a lack of awareness among clinical professionals. Despite being a relatively common and disabling disease, a large proportion of professionals are either unaware or dismissive of it. This often leads to patient neglect, which happens in clinical, government, bureaucratic, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Institut Für Qualität Und Wirtschaftlichkeit Im Gesundheitswesen
The Institute for Quality and Efficiency in Healthcare (IQWiG) () is a German agency responsible for assessing the quality and efficiency of medical treatments, including drugs, non-drug interventions (e.g. surgical procedures), diagnostic and screening methods, and treatment and disease management. IQWiG also supplies health information to patients and the general public. The organization is independent of the pharmaceutical industry, contracted solely by the Federal Ministry of Health and the Joint Federal Committee. Statuory basis IQWiG operates on a legal basis laid down in §139a and §139b of the Fifth Book of the German Social Code (SGB V) that summarises almost all provisions on statutory health insurance in Germany. History IQWiG was founded in 2004 under the directorship of Dr Peter Sawicki, who was replaced in September 2010 by Dr Jürgen Windeler. Windeler retired from the position in 2023, succeeded in the post by Dr Thomas Kaiser. Its deputy director is D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middle Age
Middle age (or middle adulthood) is the age range of the years halfway between childhood and old age. The exact range is subject to public debate, but the term is commonly used to denote the age range from 45 to 65 years. Overall This time span is generally referred to as "middle age" and can be defined as the time of ages about 40–45 to about 60–65. Many changes may occur between young adulthood and this stage. There is no universal consensus on what the exact definition of middle age is, but usual characteristics include the beginning of rapid decline of fertility, graying of hair, and other physical changes. Those in middle age continue to develop relationships and adapt to changes in relationships. Such changes are highly evident in the maturing relationships between growing or grown children and aging parents. Community involvement is fairly typical of this stage of adulthood, as is continued career development. Physical characteristics Middle-aged adults may begin t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Long COVID
Long may refer to: Measurement * Long, characteristic of something of great duration * Long, characteristic of something of great length * Longitude (abbreviation: long.), a geographic coordinate * Longa (music), note value in early music mensural notation Places Asia * Long District, Laos * Long District, Phrae, Thailand * Longjiang (other) or River Long (lit. "dragon river"), one of several rivers in China * Yangtze River or Changjiang (lit. "Long River"), China Elsewhere * Long, Somme, France People * Long (Chinese surname) * Long (Western surname) Fictional characters * Long (''Bloody Roar''), in the video game series * Long, Aeon of Permanence in Honkai: Star Rail Sports * Long, a fielding term in cricket * Long, in tennis and similar games, beyond the service line during a serve and beyond the baseline during play Other uses * , a U.S. Navy ship name * Long (finance), a position in finance, especially stock markets * Lòng, name for a laneway in Sh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pacing (activity Management)
Pacing is an activity management technique for managing a long-term health condition or disability, aiming to maximize what a person can do while reducing, or at least controlling, any symptoms that restrict activity. Patients with varying fatigue-causing conditions such as Multiple Sclerosis, Lupus, and Rheumatoid Arthritis can benefit from exercise with pacing Pacing is commonly used to help manage conditions that cause chronic pain or Fatigue#Chronic, chronic fatigue. Aims of pacing Pacing aims to manage symptoms and allow people with chronic energy-limiting conditions to be able to be as active as possible by avoiding the "boom and bust" cycle that is common among people exceeding their current, limited capacities. This often leads to being forced to stop their activities as a result of pain, fatigue, or other symptoms, and then requiring a large amount of rest before being able to resume their activity. The cycle then repeats. One goal of pacing for people with energy-limiti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differential Diagnosis
In healthcare, a differential diagnosis (DDx) is a method of analysis that distinguishes a particular disease or condition from others that present with similar clinical features. Differential diagnostic procedures are used by clinicians to diagnose the specific disease in a patient, or, at least, to consider any imminently life-threatening conditions. Often, each possible disease is called a differential diagnosis (e.g., acute bronchitis could be a differential diagnosis in the evaluation of a cough, even if the final diagnosis is common cold). More generally, a differential diagnostic procedure is a systematic diagnostic method used to identify the presence of a disease entity where multiple alternatives are possible. This method may employ algorithms, akin to the process of elimination, or at least a process of obtaining information that decreases the "probabilities" of candidate conditions to negligible levels, by using evidence such as symptoms, patient history, and medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genes
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infectious Mononucleosis
Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). Most people are infected by the virus as children, when the disease produces few or no symptoms. In young adults, the disease often results in fever, sore throat, lymphadenopathy, enlarged lymph nodes in the neck, and fatigue (medical), fatigue. Most people recover in two to four weeks; however, feeling tired may last for months. The liver or spleen may also become swollen, and in less than one percent of cases splenic rupture may occur. While usually caused by the Epstein–Barr virus, also known as human herpesvirus 4, which is a member of the herpesviridae, herpesvirus family, a few other viruses and the protozoon ''Toxoplasma gondii'' may also cause the disease. It is primarily spread through saliva but can rarely be spread through semen or blood. Spread may occur by objects such as drinking glasses or toothbrushes or through a cough or sneez ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
