Muramoylpentapeptide Carboxypeptidase
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Muramoylpentapeptide Carboxypeptidase
Muramoylpentapeptide carboxypeptidase (, ''D-alanine carboxypeptidase I'', ''DD-carboxypeptidase'', ''D-alanine carboxypeptidase'', ''D-alanyl-D-alanine carboxypeptidase'', ''D-alanine-D-alanine-carboxypeptidase'', ''carboxypeptidase D-alanyl-D-alanine'', ''carboxypeptidase I'', ''UDP-N-acetylmuramoyl-tetrapeptidyl-D-alanine alanine-hydrolase'', ''D-alanyl-D-alanine peptidase'', ''DD-peptidase'', ''penicillin binding protein 5'', ''PBP5'', ''PdcA'', ''VanY'') is an enzyme. This enzyme catalyses the following chemical reaction. : Cleavage of the bond UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-6-carboxy-L-lysyl-D-alanyl--D-alanine Alanine (symbol Ala or A), or α-alanine, is an α-amino acid that is used in the biosynthesis of proteins. It contains an amine, amine group and a carboxylic acid, carboxylic acid group, both attached to the central carbon atom which also carri ... This bacterial enzyme that requires a divalent cation for activity. References External links ...
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Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ...
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Catalysis
Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quickly, very small amounts of catalyst often suffice; mixing, surface area, and temperature are important factors in reaction rate. Catalysts generally react with one or more reactants to form intermediates that subsequently give the final reaction product, in the process of regenerating the catalyst. The rate increase occurs because the catalyst allows the reaction to occur by an alternative mechanism which may be much faster than the noncatalyzed mechanism. However the noncatalyzed mechanism does remain possible, so that the total rate (catalyzed plus noncatalyzed) can only increase in the presence of the catalyst and never decrease. Catalysis may be classified as either homogeneous, whose components are dispersed in the same phase (usual ...
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Chemical Reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, energy change as new products are generated. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the Atomic nucleus, nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive Chemical element, elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reagent, reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more Product (c ...
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D-alanine
Alanine (symbol Ala or A), or α-alanine, is an α-amino acid that is used in the biosynthesis of proteins. It contains an amine, amine group and a carboxylic acid, carboxylic acid group, both attached to the central carbon atom which also carries a methyl group side chain. Consequently it is classified as a Chemical polarity, non-polar, Aliphatic compound, aliphatic α-amino acid. Under biological conditions, it exists in its zwitterionic form with its amine group protonated (as ) and its carboxyl group deprotonated (as ). It is non-essential to humans as it can be synthesized human metabolism, metabolically and does not need to be present in the diet. It is Genetic code, encoded by all codons starting with Guanine, GCytosine, C (GCUracil, U, GCC, GCAdenine, A, and GCG). The L-isomer of alanine (chirality, left-handed) is the one that is incorporated into proteins. L-alanine is second only to L-leucine, L-leucine in rate of occurrence, accounting for 7.8% of the primary struct ...
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