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Milk Sickness
Milk sickness, also known as tremetol vomiting or, in animals, as trembles, is a kind of poisoning, characterized by trembling, vomiting, and severe intestinal pain, that affects individuals who ingest milk, other dairy products, or meat from a cow that has fed on white snakeroot plant, which contains the poison tremetol. Although very rare today, milk sickness claimed thousands of lives among migrants to the Midwestern United States in the early 19th century, especially in frontier areas along the Ohio River Valley and its tributaries where white snakeroot was prevalent. New settlers were unfamiliar with the plant and its properties. A notable victim was Nancy Hanks Lincoln, the mother of Abraham Lincoln, who died in 1818. Nursing calves and lambs may have also died from their mothers' milk contaminated with snakeroot, although the adult cows and sheep showed no signs of poisoning. Cattle, horses, and sheep are the animals most often poisoned. Anna Pierce Hobbs Bixby is credit ...
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Bloodletting
Bloodletting (or blood-letting) is the withdrawal of blood from a patient to prevent or cure illness and disease. Bloodletting, whether by a physician or by leeches, was based on an ancient system of medicine in which blood and other bodily fluids were regarded as " humours" that had to remain in proper balance to maintain health. It is claimed to have been the most common medical practice performed by surgeons from antiquity until the late 19th century, a span of over 2,000 years. In Europe, the practice continued to be relatively common until the end of the 19th century.B.) Anderson, Julie, Emm Barnes, and Enna Shackleton. "The Art of Medicine: Over 2,000 Years of Images and Imagination ardcover" The Art of Medicine: Over 2, 000 Years of Images and Imagination: Julie Anderson, Emm Barnes, Emma Shackleton: : The Ilex Press Limited, 2013. The practice has now been abandoned by modern-style medicine for all except a few very specific medical conditions. In the overwhel ...
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Philadelphia, Pennsylvania
Philadelphia, often called Philly, is the List of municipalities in Pennsylvania#Municipalities, largest city in the Commonwealth (U.S. state), Commonwealth of Pennsylvania, the List of United States cities by population, sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic (United States), Mid-Atlantic regions after New York City. Act of Consolidation, 1854, Since 1854, the city has been coextensive with Philadelphia County, Pennsylvania, Philadelphia County, the List of counties in Pennsylvania, most populous county in Pennsylvania and the urban core of the Delaware Valley, the Metropolitan statistical area, nation's seventh-largest and one of List of largest cities, world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 United States census, 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, ...
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Hardin County, Illinois
Hardin County is a county located in the U.S. state of Illinois. According to the 2020 census, it has a population of 3,649, making it the least populous county in Illinois. Its county seat is Elizabethtown. Hardin County is located in the part of the state known as Little Egypt. Hardin County was named for Hardin County, Kentucky, which was named in honor of Colonel John Hardin, an officer in the American Revolutionary War and the Northwest Indian War. History Hardin County was formed in 1839 from Pope County. Additional area was later added from Gallatin County. Hardin County was named for Hardin County, Kentucky, which was named in honor of Colonel John Hardin, an officer in the American Revolutionary War and the Northwest Indian War. Hardin was murdered by Shawnee Indians while he was on a peace mission in 1792 for President George Washington, in what is now Shelby County, Ohio. In the 1790s and early 1800s, the Hardin County area, especially Cave-In-Rock, was not ...
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Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Les ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research.Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells, Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function. Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenom ...
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Kentucky General Assembly
The Kentucky General Assembly, also called the Kentucky Legislature, is the state legislature (United States), state legislature of the U.S. state of Kentucky. It comprises the Kentucky Senate and the Kentucky House of Representatives. The General Assembly meets annually in the state Kentucky State Capitol, capitol building in Frankfort, Kentucky, convening on the first Tuesday after the first Monday in January. In even-numbered years, sessions may not last more than 60 legislative days, and cannot extend beyond April 15. In odd-numbered years, sessions may not last more than 30 legislative days, and cannot extend beyond March 30. Special sessions may be called by the Governor of Kentucky at any time for any duration. History The first meeting of the General Assembly occurred in 1792, shortly after Kentucky was granted statehood. Legislators convened in Lexington, Kentucky, Lexington, the state's temporary capital. Among the first orders of business was choosing a permanent stat ...
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Green River (Kentucky)
The Green River is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map , accessed June 13, 2011 tributary of the Ohio River that rises in Lincoln County in south-central Kentucky. Tributaries of the Green River include the Barren River, the Nolin River, the Pond River and the Rough River. The river was named after Nathanael Greene, a general of the American Revolutionary War. History Following the Revolutionary War, many veterans staked claims along the Green River as payment for their military service. The river valley also attracted several vagrants, earning it the dubious nickname Rogue's Harbor. In 1842, the Green River was canalized, with a series of locks and dams being built to create a navigable channel as far inland as Bowling Green, Kentucky. Four locks and dams were constructed on the Green River, and one lock and dam was built on the Barren River, a tributary that passed through Bowling Green. During the Ameri ...
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Henderson County, Kentucky
Henderson County is a county in the U.S. state of Kentucky. The county is located in western Kentucky on the Ohio River across from Evansville, Indiana. As of the 2020 United States census, 2020 census, the population was 44,793. Its county seat is Henderson, Kentucky, Henderson. The county was formed in 1798 and named for Richard Henderson (jurist), Richard Henderson who purchased of land from the Cherokee Indians, part of which would later make up the county. Henderson County lies within the West Kentucky Coal Field area. It is also part of the Evansville, Indiana, Evansville, Indiana, IN-KY Evansville, IN-KY Metropolitan Statistical Area, Metropolitan Statistical Area. History The Transylvania Co., also known as Richard Henderson (jurist), Richard Henderson & Co., in 1775 purchased from the Cherokees a large swath of wilderness between the Kentucky River and Cumberland River, encompassing approximately half of what would become Kentucky as well as a portion of northern Te ...
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Illinois
Illinois ( ) is a state in the Midwestern United States. Its largest metropolitan areas include the Chicago metropolitan area, and the Metro East section, of Greater St. Louis. Other smaller metropolitan areas include, Peoria and Rockford, as well Springfield, its capital. Of the fifty U.S. states, Illinois has the fifth-largest gross domestic product (GDP), the sixth-largest population, and the 25th-largest land area. Illinois has a highly diverse economy, with the global city of Chicago in the northeast, major industrial and agricultural hubs in the north and center, and natural resources such as coal, timber, and petroleum in the south. Owing to its central location and favorable geography, the state is a major transportation hub: the Port of Chicago has access to the Atlantic Ocean through the Great Lakes and Saint Lawrence Seaway and to the Gulf of Mexico from the Mississippi River via the Illinois Waterway. Additionally, the Mississippi, Ohio, and W ...
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Indiana
Indiana () is a U.S. state in the Midwestern United States. It is the 38th-largest by area and the 17th-most populous of the 50 States. Its capital and largest city is Indianapolis. Indiana was admitted to the United States as the 19th state on December 11, 1816. It is bordered by Lake Michigan to the northwest, Michigan to the north, Ohio to the east, the Ohio River and Kentucky to the south and southeast, and the Wabash River and Illinois to the west. Various Indigenous peoples of the Americas, indigenous peoples inhabited what would become Indiana for thousands of years, some of whom the U.S. government expelled between 1800 and 1836. Indiana received its name because the state was largely possessed by native tribes even after it was granted statehood. Since then, settlement patterns in Indiana have reflected regional cultural segmentation present in the Eastern United States; the state's northernmost tier was settled primarily by people from New England and New York ...
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Tennessee
Tennessee ( , ), officially the State of Tennessee, is a landlocked state in the Southeastern region of the United States. Tennessee is the 36th-largest by area and the 15th-most populous of the 50 states. It is bordered by Kentucky to the north, Virginia to the northeast, North Carolina to the east, Georgia, Alabama, and Mississippi to the south, Arkansas to the southwest, and Missouri to the northwest. Tennessee is geographically, culturally, and legally divided into three Grand Divisions of East, Middle, and West Tennessee. Nashville is the state's capital and largest city, and anchors its largest metropolitan area. Other major cities include Memphis, Knoxville, Chattanooga, and Clarksville. Tennessee's population as of the 2020 United States census is approximately 6.9 million. Tennessee is rooted in the Watauga Association, a 1772 frontier pact generally regarded as the first constitutional government west of the Appalachian Mountains. Its name derives fr ...
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