Methylornithine Synthase
Methylornithine may refer to: * 3-Methylornithine 3-Methylornithine is an amino acid with the formula H2N(CH2)2CH(CH3)CH(NH2)CO2H. This amino acid contains two stereogenic centers, but only one stereoisomer (namely (3''R'')-3-methyl-D-ornithine) occurs in nature. It is produced from lysine by th ... * ''N''-Methylornithine {{Short pages monitor ...
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3-Methylornithine
3-Methylornithine is an amino acid with the formula H2N(CH2)2CH(CH3)CH(NH2)CO2H. This amino acid contains two stereogenic centers, but only one stereoisomer (namely (3''R'')-3-methyl-D-ornithine) occurs in nature. It is produced from lysine by the action of the enzyme methylornithine synthase. The combination of lysine and 3-methylornithine, also mediated enzymatically, produces pyrrolysine, which, for some organisms, is a 22nd genetically coded amino acid.Quitterer, F.; Beck, P.; Bacher, A.; Groll, M., "Structure and Reaction Mechanism of Pyrrolysine Synthase (PylD)", Angew. Chem. Int. Ed. 2013, volume 52, pp. 7033-7037. See also * Ornithine Ornithine is a non-proteinogenic α-amino acid that plays a role in the urea cycle. It is not incorporated into proteins during translation. Ornithine is abnormally accumulated in the body in ornithine transcarbamylase deficiency, a disorder of th ... References {{DEFAULTSORT:Methylornithine, 3- Alpha-Amino acids Basic amino aci ...
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