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Mesonephros
The mesonephros ( el, middle kidney) is one of three excretory organs that develop in vertebrates. It serves as the main excretory organ of aquatic vertebrates and as a temporary kidney in reptiles, birds, and mammals. The mesonephros is included in the Wolffian body after Caspar Friedrich Wolff who described it in 1759. (The Wolffian body is composed of: mesonephros + paramesonephrotic blastema) Structure The mesonephros acts as a structure similar to the kidney that, in humans, functions between the sixth and tenth weeks of embryological life. Despite the similarity in structure, function, and terminology, however, the mesonephric nephrons do not form any part of the mature kidney or nephrons. In humans, the mesonephros consists of units which are similar in structure and function to nephrons of the adult kidney. Each of these consists of a glomerulus, a tuft of capillaries which arises from lateral branches of dorsal aorta and drains into the inferior cardinal vein; a Bowman' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intermediate Mesoderm
Intermediate mesoderm or intermediate mesenchyme is a narrow section of the mesoderm (one of the three primary germ layers) located between the paraxial mesoderm and the lateral plate of the developing embryo. The intermediate mesoderm develops into vital parts of the urogenital system (kidneys, gonads and respective tracts). Early formation Factors regulating the formation of the intermediate mesoderm are not fully understood. It is believed that bone morphogenic proteins, or BMPs, specify regions of growth along the dorsal-ventral axis of the mesoderm and plays a central role in formation of the intermediate mesoderm. Vg1/ Nodal signalling is an identified regulator of intermediate mesoderm formation acting through BMP signalling. Excess Vg1/Nodal signalling during early gastrulation stages results in expansion of the intermediate mesoderm at the expense of the adjacent paraxial mesoderm, whereas inhibition of Vg1/Nodal signalling represses intermediate mesoderm formation. A li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pronephros
Pronephros is the most basic of the three excretory organs that develop in vertebrates, corresponding to the first stage of kidney development. It is succeeded by the mesonephros, which in fish and amphibians remains as the adult kidney. In amniotes the mesonephros is the embryonic kidney and a more complex metanephros acts as the adult kidney. Once a more advanced kidney forms, the previous version typically degenerates by apoptosis or becomes part of the male reproductive system. The pronephros develops from the intermediate mesoderm, as do the later kidneys. It is a paired organ, consisting of a single giant nephron that processes blood filtrate produced from glomeruli or glomera- large embryonic glomeruli. The filtrate is deposited into the coelom. It then passes through thin ciliated tubules into the pronephric nephron where it is processed for solute recovery. The organ is active in adult forms of some primitive fish, like lampreys or hagfish. It is present at the embryo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kidney
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid–base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Kidney
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid–base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains only ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metanephros
Kidney development, or nephrogenesis, describes the embryologic origins of the kidney, a major organ in the urinary system. This article covers a 3 part developmental process that is observed in most reptiles, birds and mammals, including humans. Nephrogenesis is often considered in the broader context of the development of the urinary and reproductive organs. Phases The development of the kidney proceeds through a series of successive phases, each marked by the development of a more advanced kidney: the archinephros, pronephros, mesonephros, and metanephros. The pronephros is the most immature form of kidney, while the metanephros is most developed. The metanephros persists as the definitive adult kidney. Archinephros The archinephros is considered as hypothetical or primitive kidney. Pronephros The pronephros develops in the cervical region of the embryo. During approximately day 22 of human gestation, the paired pronephri appears towards the cranial end of the intermediate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mesonephric Duct
The mesonephric duct (also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct) is a paired organ that forms during the embryonic development of humans and other mammals and gives rise to male reproductive organs. Structure The mesonephric duct connects the primitive kidney, the '' mesonephros'', to the cloaca. It also serves as the primordium for male urogenital structures including the epididymis, vas deferens, and seminal vesicles. Development In both male and female the mesonephric duct develops into the trigone of urinary bladder, a part of the bladder wall, but the sexes differentiate in other ways during development of the urinary and reproductive organs. Male In a male, it develops into a system of connected organs between the efferent ducts of the testis and the prostate, namely the epididymis, the vas deferens, and the seminal vesicle. The prostate forms from the urogenital sinus and the efferent ducts form from the mesonephri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caspar Friedrich Wolff
Caspar Friedrich Wolff (18 January 1733 – 22 February 1794) was a German physiologist and one of the founders of embryology. Life Wolff was born in Berlin, Brandenburg. In 1759 he graduated as an M.D. from the University of Halle with his dissertation "Theoria Generationis" where he revived and supported the theory of epigenesis previously proposed by Aristotle and William Harvey. The paper consisted of three parts devoted to (1) development of plants, (2) development of animals, and (3) theoretical considerations. It indicated that organs are formed in differentiated layers from undifferentiated cells. Traditional and prevailing theory had speculated that organisms were already preformed in the seed (theory of preformation), that is in the human a homunculus was already sitting in the sperm. His views were not well received. Albrecht von Haller was a powerful antagonist. During the Seven Years' War, Wolff was required to practice as a field doctor in the Prussian Army. Thereaf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paramesonephric Ducts
Paramesonephric ducts (or Müllerian ducts) are paired ducts of the embryo that run down the lateral sides of the genital ridge and terminate at the sinus tubercle in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper one-third of the vagina. Development The female reproductive system is composed of two embryological segments: the urogenital sinus and the paramesonephric ducts. The two are conjoined at the sinus tubercle. Paramesonephric ducts are present on the embryo of both sexes. Only in females do they develop into reproductive organs. They degenerate in males of certain species, but the adjoining mesonephric ducts develop into male reproductive organs. The sex based differences in the contributions of the paramesonephric ducts to reproductive organs is based on the presence, and degree of presence, of Anti-Müllerian hormone. During the formation of the reproductive system, the paramesonephric ducts ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epididymis
The epididymis (; plural: epididymides or ) is a tube that connects a testicle to a vas deferens in the male reproductive system. It is a single, narrow, tightly-coiled tube in adult humans, in length. It serves as an interconnection between the multiple efferent ducts at the rear of a testicle (proximally), and the vas deferens (distally). Anatomy The epididymis is situated posterior and somewhat lateral to the testis. The epididymis is invested completely by the tunica vaginalis (which is continuous with the tunica vaginalis covering the testis). The epididymis can be divided into three main regions: * The head ( la, caput). The head of the epididymis receives spermatozoa via the efferent ducts of the mediastinium of the testis at the superior pole of the testis. The head is characterized histologically by a thick epithelium with long stereocilia (described below) and a little smooth muscle. It is involved in absorbing fluid to make the sperm more concentrated. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paradidymis
The term paradidymis (organ of Giraldés) is applied to a small collection of convoluted tubules, situated in front of the lower part of the spermatic cord, above the head of the epididymis. These tubes are lined with columnar ciliated epithelium, and probably represent the remains of a part of the Wolffian body, like the epididymis, but are functionless and vestigial. The Wolffian body operates as a kidney (mesonephros The mesonephros ( el, middle kidney) is one of three excretory organs that develop in vertebrates. It serves as the main excretory organ of aquatic vertebrates and as a temporary kidney in reptiles, birds, and mammals. The mesonephros is included ...) in fishes and amphibians, but the corresponding tissue is co-opted to form parts of the male reproductive system in other classes of vertebrate. The paradidymis represents a remnant of an unused, atrophied part of the Wolffian body. References {{Authority control Scrotum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
