Manchineel
The manchineel tree (''Hippomane mancinella'') is a species of flowering plant in the spurge family (Euphorbiaceae). Its native range stretches from tropical southern North America to northern South America. The name ''manchineel'' (sometimes spelled ''manchioneel'' or ''manchineal''), as well as the specific epithet ''mancinella'', are from Spanish ('little apple'), from the superficial resemblance of its fruit and leaves to those of an apple tree. It is also called beach apple. A present-day Spanish name is , 'little apple of death'. This refers to the fact that manchineel is one of the most toxic trees in the world: it has milky-white sap that contains numerous toxins and can cause blistering. The sap is present in every part of the tree—bark, leaves, and fruit. Description ''Hippomane mancinella'' grows up to tall. It has reddish-grayish bark, small greenish-yellow flowers, and shiny green leaves. The leaves are simple, alternate, very finely serrated or toothed, and l ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phorbol
Phorbol is a natural, plant-derived organic compound. It is a member of the tigliane family of terpene, diterpenes. Phorbol was first isolated in 1934 via the hydrolysis of croton oil, which is derived from the seeds of the purging croton, ''Croton tiglium''. The structure of phorbol was determined in 1967. Various phorbol esters, esters of phorbol have important biological properties, the most notable of which is the capacity to act as tumor promotion, tumor promoters through activation of protein kinase C. They mimic diglyceride, diacylglycerols, glycerol derivatives in which two hydroxyl groups have reacted with fatty acids to form esters. The most common and potent phorbol ester is 12-O-Tetradecanoylphorbol-13-acetate, 12-''O''-tetradecanoylphorbol-13-acetate (TPA), also called phorbol-12-myristate-13-acetate (PMA), which is used as a biomedical research tool in contexts such as models of carcinogenesis. History and source Phorbol is a natural product found in many plants, e ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ctenosaura Similis
''Ctenosaura similis'', commonly known as the black iguanaLiner, Ernest A. and Gustavo Cass-Andreu. (2008). ''Standard Spanish, English and Scientific Names of the Amphibians and Reptiles of Mexico (2nd. ed.).'' Herpetological Circular No. 38. Society for the Study of Amphibians and Reptiles. iv, 162 pp. or black spiny-tailed iguana, is an iguanid lizard native to Mexico and Central America. It has been reported in some Colombian islands in the Caribbean Sea and Pacific Ocean, and has been introduced to the United States in the state of Florida. The largest species in the genus ''Ctenosaura'', it is commonly found in areas such as grasslands and forests. Taxonomy ''C. similis'' was first described by British zoologist John Edward Gray in 1831. The generic name—''Ctenosaura''—is derived from two Greek words: ''ctenos'' (Κτενός), meaning "comb" (referring to the comblike spines on the lizard's back and tail), and ''saura'' (σαύρα), meaning "lizard". The specific ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sand
Sand is a granular material composed of finely divided mineral particles. Sand has various compositions but is usually defined by its grain size. Sand grains are smaller than gravel and coarser than silt. Sand can also refer to a textural class of soil or soil type; i.e., a soil containing more than 85 percent sand-sized particles by mass. The composition of sand varies, depending on the local rock sources and conditions, but the most common constituent of sand in inland continental settings and non-tropical coastal settings is silica (silicon dioxide, or SiO2), usually in the form of quartz. Calcium carbonate is the second most common type of sand. One such example of this is aragonite, which has been created over the past 500million years by various forms of life, such as coral and shellfish. It is the primary form of sand apparent in areas where reefs have dominated the ecosystem for millions of years, as in the Caribbean. Somewhat more rarely, sand may be composed ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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French West Indies
The French West Indies or French Antilles (, ; ) are the parts of France located in the Antilles islands of the Caribbean: * The two overseas departments of: ** Guadeloupe, including the islands of Basse-Terre, Grande-Terre, Les Saintes, Marie-Galante, and La Désirade. ** Martinique * The two overseas collectivities of: ** Saint Martin, the northern half of the island with the same name, the southern half is Sint Maarten, a constituent country of the Kingdom of the Netherlands. ** Saint Barthélemy History Pierre Belain d'Esnambuc was a French trader and adventurer in the Caribbean, who established the first permanent French colony, Saint-Pierre, on the island of Martinique in 1635. Belain sailed to the Caribbean in 1625, hoping to establish a French settlement on the island of St. Christopher (St. Kitts). In 1626 he returned to France, where he won the support of Cardinal Richelieu to establish French colonies in the region. Richelieu became a shareholder in the C ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Curaçao
Curaçao, officially the Country of Curaçao, is a constituent island country within the Kingdom of the Netherlands, located in the southern Caribbean Sea (specifically the Dutch Caribbean region), about north of Venezuela. Curaçao includes the main island of Curaçao and the much smaller, uninhabited island of Klein Curaçao ("Little Curaçao"). Curaçao has a population of 158,665 (January 2019 estimate), with an area of ; its capital is Willemstad. Together with Aruba and Bonaire, Curaçao forms the ABC islands (Leeward Antilles), ABC islands. Collectively, Curaçao, Aruba, and other Dutch islands in the Caribbean are often called the Dutch Caribbean. It is the largest of the ABC islands in terms of area, as well as in terms of population, and is the largest in the Dutch Caribbean. The island's name "Curaçao" may originate from the indigenous autonym of its people; this idea is supported by early Spanish accounts referring to the inhabitants as Indios Curaçaos. Curaç ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Edema
Edema (American English), also spelled oedema (British English), and also known as fluid retention, swelling, dropsy and hydropsy, is the build-up of fluid in the body's tissue (biology), tissue. Most commonly, the legs or arms are affected. Symptoms may include skin that feels tight, the area feeling heavy, and joint stiffness. Other symptoms depend on the underlying cause. Causes may include Chronic venous insufficiency, venous insufficiency, heart failure, kidney problems, hypoalbuminemia, low protein levels, liver problems, deep vein thrombosis, infections, kwashiorkor, angioedema, certain medications, and lymphedema. It may also occur in immobile patients (stroke, spinal cord injury, aging), or with temporary immobility such as prolonged sitting or standing, and during menstruation or pregnancy. The condition is more concerning if it starts suddenly, or pain or shortness of breath is present. Treatment depends on the underlying cause. If the underlying mechanism involve ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fruit
In botany, a fruit is the seed-bearing structure in flowering plants (angiosperms) that is formed from the ovary after flowering. Fruits are the means by which angiosperms disseminate their seeds. Edible fruits in particular have long propagated using the movements of humans and other animals in a symbiotic relationship that is the means for seed dispersal for the one group and nutrition for the other; humans, and many other animals, have become dependent on fruits as a source of food. Consequently, fruits account for a substantial fraction of the world's agricultural output, and some (such as the apple and the pomegranate) have acquired extensive cultural and symbolic meanings. In common language and culinary usage, ''fruit'' normally means the seed-associated fleshy structures (or produce) of plants that typically are sweet (or sour) and edible in the raw state, such as apples, bananas, grapes, lemons, oranges, and strawberries. In botanical usage, the term ''fruit'' als ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Keratoconjunctivitis
Keratoconjunctivitis is a term used to describe inflammation of both the cornea (the clear, front part of the eye) and the conjunctiva (the thin, transparent membrane covering the white part of the eye and lining the inside of the eyelids). This condition can have various causes, and its presentation may vary depending on the underlying factors. When only the cornea is inflamed, it is called '' keratitis''; when only the conjunctiva is inflamed, it is called ''conjunctivitis''. __TOC__ Causes There are several potential causes of the inflammation: * Keratoconjunctivitis sicca is used when the inflammation is due to dryness. ("Sicca" means "dryness" in medical contexts.) It occurs with 20% of rheumatoid arthritis patients. * The term " vernal keratoconjunctivitis" (VKC) is used to refer to keratoconjunctivitis occurring in spring, and is usually considered to be due to allergens. * "Atopic keratoconjunctivitis" is one manifestation of atopy. * " Adenoviral keratoconjunctivitis, al ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bullous Drug Reaction
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails). While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described. Classification of these conditions often presents many nosological challenges, since underlying causes and pathogenetics are often not known. Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology ( chronic blistering conditions), cause (skin conditions resul ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Smoke
Smoke is an aerosol (a suspension of airborne particulates and gases) emitted when a material undergoes combustion or pyrolysis, together with the quantity of air that is entrained or otherwise mixed into the mass. It is commonly an unwanted by-product of fires (including stoves, candles, internal combustion engines, oil lamps, and fireplaces), but may also be used for pest control ( fumigation), communication ( smoke signals), defensive and offensive capabilities in the military ( smoke screen), cooking, or smoking (tobacco, cannabis, etc.). It is used in rituals where incense, sage, or resin is burned to produce a smell for spiritual or magical purposes. It can also be a flavoring agent and preservative. Smoke inhalation is the primary cause of death in victims of indoor fires. The smoke kills by a combination of thermal damage, poisoning and pulmonary irritation caused by carbon monoxide, hydrogen cyanide and other combustion products. Smoke is an aerosol (or mi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Allergic Contact Dermatitis
Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance; the other type being irritant contact dermatitis (ICD). Although less common than ICD, ACD is accepted to be the most prevalent form of immunotoxicity found in humans. By its allergic nature, this form of contact dermatitis is a hypersensitive reaction that is atypical within the population. The mechanisms by which these reactions occur are complex, with many levels of fine control. Their immunology centres on the interaction of immunoregulatory cytokines and discrete subpopulations of T lymphocytes. Signs and symptoms The symptoms of allergic contact dermatitis are very similar to the ones caused by irritant contact dermatitis, which makes the first even harder to diagnose. The first sign of allergic contact dermatitis is the presence of the rash or skin lesion at the site of exposure. Depending on the type of allergen causi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Toxin
A toxin is a naturally occurring poison produced by metabolic activities of living cells or organisms. They occur especially as proteins, often conjugated. The term was first used by organic chemist Ludwig Brieger (1849–1919), derived from '' toxic''. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. They vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Less strict understandings embrace naturally occurring inorganic toxins, such as arsenic. Other understandings embrace synthetic analogs of naturally occurring organic poisons as toxins, and may or may not embrace naturally oc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |