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Malaria Vaccine
Malaria vaccines are vaccines that prevent malaria, a mosquito-borne infectious disease which affected an estimated 249 million people globally in 85 malaria-endemic countries and areas and caused 608,000 deaths in 2022. The first approved vaccine for malaria is RTS,S, known by the brand name Mosquirix. , the vaccine has been given to 1.5million children living in areas with moderate-to-high malaria transmission. It requires at least three doses in infants by age 2, and a fourth dose extends the protection for another 1–2 years. The vaccine reduces hospital admissions from severe malaria by around 30%. Research continues with other malaria vaccines. The most effective malaria vaccine is the R21/Matrix-M, with a 77% efficacy rate shown in initial trials and significantly higher antibody levels than with the RTS,S vaccine. It is the first vaccine that meets the World Health Organization's (WHO) goal of a malaria vaccine with at least 75% efficacy, and only the second malaria v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, Epileptic seizure, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected ''Anopheles'' mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial Immunity (medical), resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquitoes themselves are harmed by malaria, causing reduced lifespans in those infected by it. Malaria is caused by protozoa, single-celled microorganisms of the genus ''Plasmodium''. It is spread exclusively through bites of infected female ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatocytes
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: * Protein synthesis * Protein storage * Transformation of carbohydrates * Synthesis of cholesterol, bile salts and phospholipids * Detoxification, modification, and excretion of exogenous and endogenous substances * Initiation of formation and secretion of bile Structure The typical hepatocyte is cubical with sides of 20-30 μm, (in comparison, a human hair has a diameter of 17 to 180 μm).The diameter of human hair ranges from 17 to 181 μm. The typical volume of a hepatocyte is 3.4 x 10−9 cm3. Smooth endoplasmic reticulum is abundant in hepatocytes, in contrast to most other cell types. Microanatomy Hepatocytes display an eosinophilic cytoplasm, reflecting numerous mitochondria, and basophilic stippling due to large amounts of rough endoplasmic reticulum and free ribosomes. Brown lipofuscin granules are also observed (with i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oxford
The University of Oxford is a collegiate university, collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the List of oldest universities in continuous operation, second-oldest continuously operating university globally. It expanded rapidly from 1167, when Henry II of England, Henry II prohibited English students from attending the University of Paris. When disputes erupted between students and the Oxford townspeople, some Oxford academics fled northeast to Cambridge, where they established the University of Cambridge in 1209. The two English Ancient university, ancient universities share many common features and are jointly referred to as ''Oxbridge''. The University of Oxford comprises 43 constituent colleges, consisting of 36 Colleges of the University of Oxford, semi-autonomous colleges, four permanent private halls and three societies (colleges that are depar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jenner Institute
The Jenner Institute is a research institute on the Old Road Campus in Headington, east Oxford, England. It was formed in November 2005 through a partnership between the University of Oxford and the UK Institute for Animal Health. It is associated with the Nuffield Department of Medicine, in the Medical Sciences Division of Oxford University. The institute receives charitable support from the Jenner Vaccine Foundation. The institute is led by Prof. Adrian Hill. The institute develops vaccines and carries out clinical trials for diseases including malaria, tuberculosis (vaccine MVA85A), ebola, and MERS-Coronavirus. In 2020, the institute successfully developed the Oxford–AstraZeneca COVID-19 vaccine, in a project backed by private companies including Oxford Sciences Innovation, Google Ventures, and Sequoia Capital, among others. When developed, the UK government backed trials, purchased 100million doses, and encouraged Oxford to work with AstraZeneca, a company based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BBC News
BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs in the UK and around the world. The department is the world's largest broadcast news organisation and generates about 120 hours of radio and television output each day, as well as online news coverage. The service has over 5,500 journalists working across its output including in 50 foreign news bureaus where more than 250 foreign correspondents are stationed. Deborah Turness has been the CEO of news and current affairs since September 2022. In 2019, it was reported in an Ofcom report that the BBC spent £136m on news during the period April 2018 to March 2019. BBC News' domestic, global and online news divisions are housed within the largest live newsroom in Europe, in Broadcasting House in central London. Parliamentary coverage is produced and broadcast from studios in London. Through BBC English Regions, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RTS S Vs R21 Recombinant Protein Comparison
RTS may refer to: Medicine * Rape trauma syndrome, the psychological trauma experienced by a rape victim * Revised Trauma Score, a system to evaluate injuries secondary to violent trauma * Rubinstein–Taybi syndrome, a condition characterized by short stature, etc. Radio and television * Royal Television Society, a UK-based society for the discussion of television * Radio-televizija Srbije, the national broadcasting company of Serbia * Radiodiffusion Télévision Sénégalaise, the Senegalese national broadcasting company * Radiotelevizija Slovenija (RTV SLO), the national broadcaster of Slovenia * Radio Télévision Suisse, the French-speaking public broadcasting company of Switzerland * Radio and Television of Slovakia (RTVS), the national broadcasting company of Slovakia * Radio & Television of Singapore, Mediacorp's name from 1963 till 1980 * RedTeleSistema, a private television station in Ecuador * SES/RTS, the callsign of a TV station in Loxton, South Australia Technology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UNICEF
UNICEF ( ), originally the United Nations International Children's Emergency Fund, officially United Nations Children's Fund since 1953, is an agency of the United Nations responsible for providing Humanitarianism, humanitarian and Development aid, developmental aid to children worldwide. The organization is one of the most widely known and visible social welfare entities globally, operating in 192 countries and territories. UNICEF's activities include providing immunizations and disease prevention, administering Antiretroviral drug, treatment for children and mothers with HIV, enhancing childhood and maternal nutrition, improving sanitation, promoting education, and providing emergency relief in response to disasters. UNICEF is the successor of the United Nations International Children's Emergency Fund, and was created on 11 December 1946, in New York, by the United Nations Relief and Rehabilitation Administration, U.N. Relief Rehabilitation Administration to provide immediate r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kenya
Kenya, officially the Republic of Kenya, is a country located in East Africa. With an estimated population of more than 52.4 million as of mid-2024, Kenya is the 27th-most-populous country in the world and the 7th most populous in Africa. Kenya's capital and largest city is Nairobi. Its second-largest and oldest city is Mombasa, a major port city located on Mombasa Island. Other major cities within the country include Kisumu, Nakuru & Eldoret. Going clockwise, Kenya is bordered by South Sudan to the northwest (though much of that border includes the disputed Ilemi Triangle), Ethiopia to the north, Somalia to the east, the Indian Ocean to the southeast, Tanzania to the southwest, and Lake Victoria and Uganda to the west. Kenya's geography, climate and population vary widely. In western, rift valley counties, the landscape includes cold, snow-capped mountaintops (such as Batian, Nelion and Point Lenana on Mount Kenya) with vast surrounding forests, wildlife and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malawi
Malawi, officially the Republic of Malawi, is a landlocked country in Southeastern Africa. It is bordered by Zambia to the west, Tanzania to the north and northeast, and Mozambique to the east, south, and southwest. Malawi spans over and has an estimated population of 21,240,689 (as of 2024). Lilongwe is its capital and largest city, while the next three largest cities are Blantyre, Mzuzu, and Zomba, the former capital. The part of Africa now known as Malawi was settled around the 10th century by the Akafula, also known as the Abathwa. Later, the Bantu groups came and drove out the Akafula and formed various kingdoms such as the Maravi and Nkhamanga kingdoms, among others that flourished from the 16th century. In 1891, the area was colonised by the British as the British Central African Protectorate, and it was renamed '' Nyasaland'' in 1907. In 1964, Nyasaland became an independent country as a Commonwealth realm under Prime Minister Hastings Banda, and was rena ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Medicines Agency
The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of pharmaceutical products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency (EMEA).Set up by EC Regulation No. 2309/93 as the European Agency for the Evaluation of Medicinal Products, and renamed by EC Regulation No. 726/2004 to the European Medicines Agency, it had the acronym EMEA until December 2009. The European Medicines Agency does not call itself EMA either – it has no official acronym but may reconsider if EMA becomes commonly accepted (secommunication on new visual identity an). The EMA was set up in 1995, with funding from the European Union and the pharmaceutical industry, as well as indirect subsidy from member states, its stated intention to harmonise (but not replace) the work of existing national medicine regulatory bodies. The hope was that this plan would ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adjuvant
In pharmacology, an adjuvant is a drug or other substance, or a combination of substances, that is used to increase the efficacy or potency of certain drugs. Specifically, the term can refer to: * Adjuvant therapy in cancer management * Analgesic adjuvant in pain management * Immunologic adjuvant In immunology, an adjuvant is a substance that increases or modulates the immune response to a vaccine. The word "adjuvant" comes from the Latin word , meaning to help or aid. "An immunologic adjuvant is defined as any substance that acts to acce ... in vaccines {{sia Adjuvants ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
