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Kansas
Kansas ( ) is a landlocked U.S. state, state in the Midwestern United States, Midwestern region of the United States. It borders Nebraska to the north; Missouri to the east; Oklahoma to the south; and Colorado to the west. Kansas is named after the Kansas River, in turn named after the Kaw people, Kansa people. Its List of capitals in the United States, capital is Topeka, Kansas, Topeka, and its List of cities in Kansas, most populous city is Wichita, Kansas, Wichita; however, the largest urban area is the bi-state Kansas City metropolitan area split between Kansas and Missouri. For thousands of years, what is now Kansas was home to numerous and diverse Plains Indians, Indigenous tribes. The first settlement of non-indigenous people in Kansas occurred in 1827 at Fort Leavenworth. The pace of settlement accelerated in the 1850s, in the midst of political wars over the Slavery in the United States, slavery debate. When it was officially opened to settlement by the U.S. governm ...
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Kaposi's Sarcoma
Kaposi's sarcoma (KS) is a type of cancer that can form masses on the skin, in lymph nodes, in the mouth, or in other organs. The skin lesions are usually painless, purple and may be flat or raised. Lesions can occur singly, multiply in a limited area, or may be widespread. Depending on the sub-type of disease and level of immune suppression, KS may worsen either gradually or quickly. Except for classic KS where there is generally no immune suppression, KS is caused by a combination of Immunosuppression, immune suppression (such as due to HIV/AIDS) and infection by Human herpesvirus 8 (HHV8 – also called KS-associated herpesvirus (KSHV)). Classic, endemic, immunosuppression therapy-related (also known as iatrogenic), and epidemic (also known as AIDS-related) sub-types are all described. Classic KS tends to affect older men in regions where KSHV is highly prevalent (Mediterranean, Eastern Europe, Middle East), is usually slow-growing, and most often affects only the legs. Endem ...
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Kolmogorov–Smirnov Test
In statistics, the Kolmogorov–Smirnov test (also K–S test or KS test) is a nonparametric statistics, nonparametric test of the equality of continuous (or discontinuous, see #Discrete and mixed null distribution, Section 2.2), one-dimensional probability distributions. It can be used to test whether a random sample, sample came from a given reference probability distribution (one-sample K–S test), or to test whether two samples came from the same distribution (two-sample K–S test). Intuitively, it provides a method to qualitatively answer the question "How likely is it that we would see a collection of samples like this if they were drawn from that probability distribution?" or, in the second case, "How likely is it that we would see two sets of samples like this if they were drawn from the same (but unknown) probability distribution?". It is named after Andrey Kolmogorov and Nikolai Smirnov (mathematician), Nikolai Smirnov. The Kolmogorov–Smirnov statistic quantifies ...
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Keratan Sulfate
Keratan sulfate (KS), also called keratosulfate, is any of several sulfated glycosaminoglycans (structural carbohydrates) that have been found especially in the cornea, cartilage, and bone. It is also synthesized in the central nervous system where it participates both in development and in the glial scar formation following an injury. Keratan sulfates are large, highly hydrated molecules which in joints can act as a cushion to absorb mechanical shock. Structure Like other glycosaminoglycans keratan sulfate is a linear polymer that consists of a repeating disaccharide unit. Keratan sulfate occurs as a proteoglycan (PG) in which KS chains are attached to cell-surface or extracellular matrix proteins, termed core proteins. KS core proteins include lumican, keratocan, mimecan, fibromodulin, PRELP, osteoadherin, and aggrecan. The basic repeating disaccharide unit within keratan sulfate is -3 Galβ1-4 GlcNAc6Sβ1-. This can be sulfated at carbon position 6 (C6) of either or bot ...
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Ketoacyl Synthase
Ketoacyl synthases (KSs) catalyze the condensation reaction of acyl-CoA or acyl-acyl ACP with malonyl-CoA to form 3-ketoacyl-CoA or with malonyl-ACP to form 3-ketoacyl-ACP. This reaction is a key step in the fatty acid synthesis cycle, as the resulting acyl chain is two carbon atoms longer than before. KSs exist as individual enzymes, as they do in type II fatty acid synthesis and type II polyketide synthesis, or as domains in large multidomain enzymes, such as type I fatty acid synthases (FASs) and polyketide synthases (PKSs). KSs are divided into five families: KS1, KS2, KS3, KS4, and KS5. Multidomain enzyme systems Fatty acid synthase Fatty acid synthase (FAS) is the enzyme system involved in de novo fatty acid synthesis. FAS is an iterative multienzyme consisting of several component enzymes, one of which is ketoacyl synthase. There are two types of FASs: type I and type II. Type I FASs are highly integrated multidomain enzymes. They contain discrete functional domains resp ...
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Kallmann Syndrome
Kallmann syndrome (KS) is a hereditary, genetic disorder that prevents a person from starting or fully completing puberty. Kallmann syndrome is a form of a group of conditions termed hypogonadotropic hypogonadism. To distinguish it from other forms of hypogonadotropic hypogonadism, Kallmann syndrome has the additional symptom of a anosmia, total lack of sense of smell (anosmia) or a hyposmia, reduced sense of smell. If left untreated, people will have poorly defined secondary sexual characteristics, show signs of hypogonadism, almost invariably are infertile and are at increased risk of developing osteoporosis. A range of other physical symptoms affecting the face, hands and skeletal system can also occur. Cause & Diagnosis The underlying cause is due to the defective migration of gonadotropin-releasing hormone expressing neurons (GnRH neuron, GNRH neurons) from olfactory placode to hypothalamus, leading to congenital Gonadotropin-releasing hormone, GNRH deficiency. This leads ...
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Klinefelter's Syndrome
Klinefelter syndrome (KS), also known as 47,XXY, is a chromosome anomaly where a male has an extra X chromosome. These complications commonly include infertility and small, poorly functioning testicles (if present). These symptoms are often noticed only at puberty, although this is one of the most common chromosomal disorders. The birth prevalence of KS in the State of Victoria, Australia was estimated to be 223 per 100,000 males. It is named after American endocrinologist Harry Klinefelter, who identified the condition in the 1940s, along with his colleagues at Massachusetts General Hospital. The syndrome is defined by the presence of at least one extra X chromosome in addition to a Y chromosome, yielding a total of 47 or more chromosomes rather than the usual 46. Klinefelter syndrome occurs randomly. The extra X chromosome comes from the father and mother nearly equally. An older mother may have a slightly increased risk of a child with KS. The syndrome is diagnosed by the gen ...
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Kernowek Standard
Kernowek Standard (KS, ''Standard Cornish''), its initial version spelt Kernowak Standard, is a variety of the spelling of revived Cornish. It has two specifications, the first of which was published as a draft proposal in March 2007, and the second of which was published as a practical orthography in May 2012. Kernowak Standard (KS1) Its first iteration, then spelt Kernowak Standard and now designated KS1, was developed gradually by a group called ''UdnFormScrefys'' ('Single Written Form') as part of the Cornish language community's process of agreement on a Standard Written Form (SWF) for Cornish through the public body Cornish Language Partnership. It was published as a proposal in a series of revisions, Revision 11 of which was released to the Cornish Language Commission on 26 March 2007. Revision 15 was published on 22 June 2007. Revision 16 was published on 14 November 2007. Its principal authors were Michael Everson, Neil Kennedy and Nicholas Williams.The orthography wa ...
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Norwegian Association Of Local And Regional Authorities
The Norwegian Association of Local and Regional Authorities () is an employers' organisation in Norway. It was founded in 1972 as a merger between the Union of Norwegian Cities (''Norges Byforbund'', founded in 1903) and the Norwegian Association of Rural Municipalities (''Norges Herredsforbund'', founded in 1923). The two entities were also merged between 1942 and 1945, during the German occupation of Norway The occupation of Norway by Nazi Germany during the Second World War began on 9 April 1940 after Operation Weserübung. Conventional armed resistance to the German invasion ended on 10 June 1940, and Nazi Germany controlled Norway until th .... It changed its name from ''Norske Kommuners Sentralforbund'' to ''Kommunenes Sentralforbund'' in 1988, and to just ''KS'' in 2004. The current director general is Gunn Marit Helgesen. KS President Gunn Marit Helgesen was re-elected at the KS congress February 17, together with deputies Mette Gundersen and Bjørn Arild Gram ...
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Kammersänger
Kammersänger (male; ) or Kammersängerin (female; ), abbreviated Ks. or KS, is a German Title of honor, honorific title for distinguished singers of opera and classical music. It literally means "chamber singer". Historically, the title was bestowed by princes or kings, when it was styled ''Hofkammersänger(in)'', where ''Hof'' refers to the royal court. The title is given in Germany and in Austria usually on the recommendation of relevant national and local institutions. In East Germany, some concert halls bestowed this designation. Similar titles are , Staatsschauspieler, , , and Kammerkomponist/Kammerkompositeur. Titles and recipients Austria ;Österreichischer Kammersänger / Österreichische Kammersängerin The honorary title is awarded by the Federal President of Austria on the proposal of the responsible Federal Minister since 1971. * Germany * Elise Kutscherra de Nyss (Coburg, 1894) * Gerhard Unger (1952) * Theo Adam (1955) * Anny Schlemm (Frankfurt, 1963) * Sig ...
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Key Stage
A key stage is a stage of the state education system in England, Northern Ireland, the Isle of Man and the British Overseas Territory of Gibraltar setting the educational knowledge expected of students at various ages. The term is also used in some other autonomous territories such as Hong Kong, and countries such as Australia (some states), although the ages at which each key stage applies differ between countries. Key Stages in England are often abbreviated as KS (ex. KS1). Each key stage consists of a certain range of school years so there is no key stage for higher education. In Wales, the new curriculum replaces key stages with "progression steps" at ages 5, 8, 11, 14 and 16, "relating to broad expectations of a child’s progress". Stages In England, the stages are as follows: The national curriculum sets out targets to be achieved in various subject areas at each of the Key Stages. The Key Stages were first defined in the Education Reform Act 1988 to accompany the f ...
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King's Scholar
A King's Scholar, abbreviated KS in the United Kingdom, is the recipient of a scholarship from a foundation created by, or under the auspices of, a British monarch. The scholarships are awarded at certain Public school (United Kingdom), public schools and colleges in England. These include Eton College; The King's School, Canterbury; King's Ely; The King's School, Worcester; Durham School; and Westminster School, although at Westminster their name changes depending on whether the current monarch is male or female. Under Charles III, they are King's Scholars. Historical origins On 7 July 1317, Edward II of England, King Edward II established the first King's Scholars at the University of Cambridge. On that date, a writ was sent from the king to the sheriff of Cambridgeshire stating that 12 boys from his household were being sent to study at Cambridge under the care of a master, and that the sheriff was to pay their expenses from the money he collected on the king's behalf. In ...
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