Isoflavene
Isoflavenes are a type of isoflavonoids. Examples * Glabrene, found in the roots of liquorice, is also a xenoestrogen. * 2-Methoxyjudaicin found in the roots of ''Cicer bijugum'' * Haginin D * Idronoxil, also known as phenoxodiol, which is used for anticancer purposes. References Isoflavonoids {{aromatic-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Liquorice
Liquorice ( Commonwealth English) or licorice (American English; see spelling differences; ) is the common name of ''Glycyrrhiza glabra'', a flowering plant of the bean family Fabaceae, from the root of which a sweet, aromatic flavouring is extracted. The liquorice plant is an herbaceous perennial legume native to West Asia, North Africa, and Southern Europe. Liquorice is used as a flavouring in confectionery, tobacco, beverages, and pharmaceuticals, and is marketed as a dietary supplement. Liquorice extracts have been used in herbalism and traditional medicine. Excessive consumption of liquorice (more than per day of pure glycyrrhizinic acid, a key component of liquorice) can lead to undesirable consequences. Clinically, it is suspected that overindulgence in liquorice may manifest as unexplained hypertension, low blood potassium levels ( hypokalemia), and muscle weakness in individuals. Consuming liquorice should be avoided during pregnancy. Etymology The word '' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Glabrene
Glabrene is an isoflavonoid that is found in ''Glycyrrhiza glabra'' (licorice). It has estrogenic activity, showing estrogenic effects on breast, vascular, and bone tissue, and hence is a phytoestrogen ( IC50 for estrogen receptor binding = 1 μM). It has also been found to act as a tyrosinase inhibitor ( IC50 = 3.5 μM) and to inhibit the formation of melanin in melanocytes, and for these reasons, has been suggested as a potential skin-lightening agent. See also * Glabridin * Isoliquiritigenin * Liquiritigenin Liquiritigenin is a flavanone that was isolated from ''Glycyrrhiza uralensis'', and is found in a variety of plants of the Glycyrrhiza genus, including ''Glycyrrhiza glabra'' (licorice). It is an estrogenic compound which acts as a selective agoni ... References Isoflavonoids Phytoestrogens {{alkanederivative-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Isoflavonoid
Isoflavonoids are a class of flavonoid phenolic compounds, many of which are biologically active. Isoflavonoids and their derivatives are sometimes referred to as phytoestrogens, as many isoflavonoid compounds have biological effects via the estrogen receptor. Medically, isoflavonoids and related compounds have been used in many dietary supplements but the medical and scientific community is generally skeptical of their use. Recently, some natural isoflavonoids have been identified as toxins, including biliatresone which may cause biliary atresia when infants are exposed to the plant product. The isoflavonoid group is broad, and includes many structurally similar groups, including: * isoflavones * isoflavanones * isoflavans * pterocarpans * rotenoids Isoflavonoids are derived from the flavonoid biosynthesis pathway via liquiritigenin or naringenin. Chemical makeup While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, isoflavonoids have the 3- ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Xenoestrogen
Xenoestrogens are a type of xenohormone that imitates estrogen. They can be either synthetic or natural chemical compounds. Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any organism. Natural xenoestrogens include phytoestrogens which are plant-derived xenoestrogens. Because the primary route of exposure to these compounds is by consumption of phytoestrogenic plants, they are sometimes called "dietary estrogens". Mycoestrogens, estrogenic substances from fungi, are another type of xenoestrogen that are also considered mycotoxins. Xenoestrogens are clinically significant because they can mimic the effects of endogenous estrogen and thus have been implicated in precocious puberty and other disorders of the reproductive system. Xenoestrogens include pharmac ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cicer Bijugum
''Cicer'' is a genus of the legume family, Fabaceae, and the only genus found in tribe Cicereae. It is included within the IRLC, and its native distribution is across the Middle East and Asia. Its best-known and only domesticated member is ''Cicer arietinum'', the chickpea. Species 45 species are accepted: *''Cicer acanthophyllum'' *'' Cicer anatolicum'' *''Cicer arietinum'' ** ''Cicer arietinum'' subsp. ''arietinum'' - cultivated annual chickpea ** ''Cicer arietinum'' subsp. ''reticulatum'' (synonym '' Cicer reticulatum'') *''Cicer atlanticum'' *''Cicer balcaricum'' *''Cicer baldshuanicum'' *'' Cicer bijugum'' *'' Cicer canariense'' *''Cicer chorassanicum'' *''Cicer cuneatum'' *'' Cicer echinospermum'' *''Cicer fedtschenkoi'' *''Cicer flexuosum'' *''Cicer floribundum'' *''Cicer graecum'' *''Cicer grande'' *''Cicer heterophyllum'' *''Cicer incanum'' *''Cicer incisum'' *''Cicer judaicum'' *''Cicer kermanense'' *''Cicer korshinskyi'' *''Cicer laetum'' *''Ci ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |