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Hybrizyme
Hybrizyme is a term coined to indicate novel or normally rare gene variants (or alleles) that are associated with hybrid zones, geographic areas where two related taxa (e.g. species or subspecies) meet, mate, and produce hybrid offspring. The hybrizyme phenomenon is widespread and these alleles occur commonly, if not in all hybrid zones. Initially considered to be caused by elevated rates of mutation in hybrids, the most probable hypothesis infers that they are the result of negative (purifying) selection. Namely, in the center of the hybrid zone, negative selection purges alleles against hybrid disadvantage (e.g. hybrid inviability or infertility). Stated differently, any allele that will decrease reproductive isolation is favored and any linked alleles (genetic markers) also increase their frequency by genetic hitchhiking. If the linked alleles used to be rare variants in the parental taxa, they will become more common in the area where the hybrids are formed. Etymology Original ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hybrid Zone
A hybrid zone exists where the ranges of two interbreeding species or diverged intraspecific lineages meet and cross-fertilize. Hybrid zones can form ''in situ'' due to the evolution of a new lineage but generally they result from secondary contact of the parental forms after a period of geographic isolation, which allowed their differentiation. Hybrid zones are useful in studying the genetics of speciation as they can provide natural examples of differentiation and gene flow between populations that are at some point on the continuum between diverging populations and separate species with reproductive isolation. Definition Hybrid zones are areas where the hybrid offspring of two divergent taxa (species, subspecies or genetic "forms") are prevalent and there is a cline in the genetic composition of populations from one taxon to the other. The two (or more) genetically differentiated species or lineages contributing to formation of a hybrid zone are regarded as parental forms. Pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Point Mutation
A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome. Point mutations have a variety of effects on the downstream protein product—consequences that are moderately predictable based upon the specifics of the mutation. These consequences can range from no effect (e.g. Synonymous substitution, synonymous mutations) to deleterious effects (e.g. frameshift mutations), with regard to protein production, composition, and function. Causes Point mutations usually take place during DNA replication. DNA replication occurs when one double-stranded DNA molecule creates two single strands of DNA, each of which is a template for the creation of the complementary strand. A single point mutation can change the whole DNA sequence. Changing one purine or pyrimidine may change the amino acid that the nucleotides code for. Point mutations may arise from spontaneous mutations that occur during DNA re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hybrid Swarm
A hybrid swarm is a population of hybrids that has survived beyond the initial hybrid generation, with interbreeding between hybrid individuals and backcrossing with its parent types. Such population are highly variable, with the genetic and phenotypic characteristics of individuals ranging widely between the two parent types. Hybrid swarms thus blur the boundary between the parent taxa. Precise definitions of which populations can be classified as hybrid swarms vary, with some specifying simply that all members of a population should be hybrids, while others differ in whether all members should have the same or different levels of hybridization. Hybrid swarms occur when the hybrid is viable and at least as vigorous as its parent types; and there are no barriers to crossbreeding between the hybrid and parent types. Swarms cannot occur if one of these conditions is not met: if the hybrid type has low viability, the hybrid population cannot maintain itself except by further h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Next-generation Sequencing
Massive parallel sequencing or massively parallel sequencing is any of several high-throughput approaches to DNA sequencing using the concept of massively parallel processing; it is also called next-generation sequencing (NGS) or second-generation sequencing. Some of these technologies emerged between 1993 and 1998 and have been commercially available since 2005. These technologies use miniaturized and parallelized platforms for sequencing of 1 million to 43 billion short reads (50 to 400 bases each) per instrument run. Many NGS platforms differ in engineering configurations and sequencing chemistry. They share the technical paradigm of massive parallel sequencing via spatially separated, clonally amplified DNA templates or single DNA molecules in a flow cell. This design is very different from that of Sanger sequencing—also known as capillary sequencing or first-generation sequencing—which is based on electrophoretic separation of chain-termination products produced in indiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondrial DNA, mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplast DNA, chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been Whole-genome sequencing, sequenced and various regions have been annotated. The first genome to be sequenced was that of the virus φX174 in 1977; the first genome sequence of a prokaryote (''Haemophilus influenzae'') was published in 1995; the yeast (''Saccharomyces cerevisiae'') genome was the first eukaryotic genome to be sequenced in 1996. The Human Genome Project ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Flow
In population genetics, gene flow (also known as migration and allele flow) is the transfer of genetic variation, genetic material from one population to another. If the rate of gene flow is high enough, then two populations will have equivalent allele frequencies and therefore can be considered a single effective population. It has been shown that it takes only "one migrant per generation" to prevent populations from diverging due to Genetic drift, drift. Populations can diverge due to Natural selection, selection even when they are exchanging alleles, if the selection pressure is strong enough. Gene flow is an important mechanism for transferring genetic diversity among populations. Migrants change the distribution of genetic diversity among populations, by modifying allele frequencies (the proportion of members carrying a particular variant of a gene). High rates of gene flow can reduce the genetic differentiation between the two groups, increasing homogeneity. Gene flow has b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maple
''Acer'' is a genus of trees and shrubs commonly known as maples. The genus is placed in the soapberry family Sapindaceae.Stevens, P. F. (2001 onwards). Angiosperm Phylogeny Website. Version 9, June 2008 nd more or less continuously updated since http://www.mobot.org/MOBOT/research/APweb/. There are approximately 132 species, most of which are native to Asia, with a number also appearing in Europe, northern Africa, and North America. Only one species, '' Acer laurinum'', extends to the Southern Hemisphere.Gibbs, D. & Chen, Y. (2009The Red List of Maples Botanic Gardens Conservation International (BGCI) The type species of the genus is the sycamore maple ''Acer pseudoplatanus'', one of the most common maple species in Europe.van Gelderen, C. J. & van Gelderen, D. M. (1999). '' Maples for Gardens: A Color Encyclopedia'' Most maples usually have easily identifiable palmate leaves (with a few exceptions, such as '' Acer carpinifolium'', '' Acer laurinum'', and '' Acer negundo'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alloenzyme
Alloenzymes (or also called allozymes) are variant forms of an enzyme which differ structurally but not functionally from other allozymes coded for by different alleles at the same locus. These are opposed to isozymes, which are enzymes that perform the same function, but which are coded by genes located at different loci. Alloenzymes are common biological enzymes that exhibit high levels of functional evolutionary conservation throughout specific phyla and kingdoms. They are used by phylogeneticists as molecular markers to gauge evolutionary histories and relationships between different species. This can be done because allozymes do not have the same structure. They can be separated by capillary electrophoresis. However, some species are monomorphic for many of their allozymes which would make it difficult for phylogeneticists to assess the evolutionary histories of these species. In these instances, phylogeneticists would have to use another method to determine the evolut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pocket Gophers
Pocket gophers, commonly referred to simply as gophers, are burrowing rodents of the family Geomyidae. The roughly 41 speciesSearch results for "Geomyidae" on thASM Mammal Diversity Database are all Endemism, endemic to North and Central America. They are commonly known for their extensive tunneling activities and their ability to destroy farms and gardens. The name "pocket gopher" on its own may refer to any of a number of genus, genera within the family (biology), family Geomyidae. These are the "true" gophers, but several ground squirrels in the distantly related family Sciuridae are often called "gophers", as well. The origin of the word "gopher" is uncertain; the French , meaning waffle, has been suggested, on account of the gopher tunnels resembling the honeycomb-like pattern of holes in a waffle; another suggestion is that the word is of Muskogean languages, Muskogean origin. Description Pocket gophers weigh around , and are about in body length, with a tail long. A f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alleles
An allele is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. Alleles can differ at a single position through single nucleotide polymorphisms (SNP), but they can also have insertions and deletions of up to several thousand base pairs. Most alleles observed result in little or no change in the function or amount of the gene product(s) they code or regulate for. However, sometimes different alleles can result in different observable phenotypic traits, such as different pigmentation. A notable example of this is Gregor Mendel's discovery that the white and purple flower colors in pea plants were the result of a single gene with two alleles. Nearly all multicellular organisms have two sets of chromosomes at some point in their biological life cycle; that is, they are diploid. For a given locus, if the two chromosomes contain the same allele, they, and the organism, are homozygous with respect to that allele. If the alleles are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Hitchhiking
Genetic hitchhiking, also called genetic draft or the hitchhiking effect, is when an allele changes frequency not because it itself is under natural selection, but because it is near another gene that is undergoing a selective sweep and that is on the same DNA chain. When one gene goes through a selective sweep, any other nearby polymorphisms that are in linkage disequilibrium will tend to change their allele frequencies too.Futuyma, Douglas J. 2013. Evolution: Third Edition. Sinauer Associates, Inc: Sunderland, MA. Selective sweeps happen when newly appeared (and hence still rare) mutations are advantageous and increase in frequency. Neutral or even slightly deleterious alleles that happen to be close by on the chromosome 'hitchhike' along with the sweep. In contrast, effects on a neutral locus due to linkage disequilibrium with newly appeared deleterious mutations are called background selection. Both genetic hitchhiking and background selection are stochastic (random) ev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
