Heparan Sulfate 3-O-sulfotransferase
Glucosaminyl 3-O-sulfotransferase may refer to: * (heparan sulfate)-glucosamine 3-sulfotransferase 1, an enzyme * (heparan sulfate)-glucosamine 3-sulfotransferase 2 In enzymology, a eparan sulfateglucosamine 3-sulfotransferase 2 () is an enzyme that catalyzes the chemical reaction :3'-phosphoadenylyl sulfate + eparan sulfateglucosamine \rightleftharpoons adenosine 3',5'-bisphosphate + eparan sulfategluco ..., an enzyme * (heparan sulfate)-glucosamine 3-sulfotransferase 3, an enzyme {{Enzyme index ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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(heparan Sulfate)-glucosamine 3-sulfotransferase 1
Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues. It occurs in a proteoglycan (HSPG, i.e. Heparan Sulfate ProteoGlycan) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins. In this form, HS binds to a variety of protein ligands, including Wnt, and regulates a wide range of biological activities, including developmental processes, angiogenesis, blood coagulation, abolishing detachment activity by GrB (Granzyme B), and tumour metastasis. HS has also been shown to serve as cellular receptor for a number of viruses, including the respiratory syncytial virus. One study suggests that cellular heparan sulfate has a role in SARS-CoV-2 infection, particularly when the virus attaches with ACE2. Proteoglycans The major cell membrane HSPGs are the transmembrane syndecans and the glycosylphosphatidylinositol (GPI) anchored glypicans. Other minor forms of membrane HSPG include betaglycan and the V-3 isofo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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(heparan Sulfate)-glucosamine 3-sulfotransferase 2
In enzymology, a eparan sulfateglucosamine 3-sulfotransferase 2 () is an enzyme that catalyzes the chemical reaction :3'-phosphoadenylyl sulfate + eparan sulfateglucosamine \rightleftharpoons adenosine 3',5'-bisphosphate + eparan sulfateglucosamine 3-sulfate Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and heparan sulfate-glucosamine, whereas its two products are adenine 3',5'-bis-phosphate and heparan sulfate- glucosamine 3-sulfate. This enzyme belongs to the family of transferences, specifically the transformer, which transfer sulfur-containing groups. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ... of this enzyme class is 3'-phosphorylation-sulfate: eparin sulfateglucose 3-nontransferable. Other names in common use include ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |