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Haustrum (anatomy)
The haustra (: haustrum) of the colon are the small pouches caused by sacculation (sac formation), which give the colon its segmented appearance. The teniae coli run the length of the colon. A proposed explanation for the existence of haustra is that the colon becomes sacculated between the teniae coli because the taenia coli are shorter than the colon. However, it is now more commonly accepted that the haustra form because of enteric nervous system activity. Haustral contractions are slow segmenting, uncoordinated movements that occur approximately every 25 minutes. One haustrum distends as it fills with chyme, which stimulates muscles to contract, pushing the contents to the next haustrum. Also see peristalsis. There is a wider distance between haustra than between the circular folds of the small intestine, and the haustra do not reach around the entire circumference of the intestine, in contrast to circular folds of the small intestine that do. These differences can assist i ...
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Colon (anatomy)
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The colon (progressing from the ascending colon to the transverse, the descending and finally the sigmoid colon) is the longest portion of the large intestine, and the terms "large intestine" and "colon" are often used interchangeably, but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending the abdomen, across the width of the abdominal cavity as the transverse colon, and then desce ...
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Teniae Coli
The taeniae coli (also teniae coli or tenia coli) are three separate longitudinal ribbons (''taeniae'' meaning ribbon in Latin) of smooth muscle on the outside of the ascending, transverse, descending and sigmoid colons. They are visible and can be seen just below the serosa or fibrosa. There are three teniae coli: mesocolic, free and omental taeniae coli. The teniae coli contract lengthwise to produce the haustra, the bulges in the colon. The bands converge at the root of the vermiform appendix. At the rectosigmoid junction, the taeniae spread out and unite to form the longitudinal muscle layer. In the caecum, the ascending colon, the descending colon and sigmoid colon the positions of these bands are fixed. The taenia libera, is placed anteriorly in the caecum, ascending, descending and sigmoid colon, but is placed inferiorly in the transverse colon. The taenia mesocolica is present on the posteromedial surface of the caecum, ascending, descending and sigmoid colon, but is ...
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Enteric Nervous System
The enteric nervous system (ENS) is one of the three divisions of the autonomic nervous system (ANS), the others being the sympathetic nervous system (SNS) and parasympathetic nervous system (PSNS). It consists of a mesh-like system of neurons that governs the function of the gastrointestinal tract. The ENS is nicknamed the "second brain". It is derived from neural crest cells. The enteric nervous system is capable of operating independently of the brain and spinal cord, but is thought to rely on innervation from the vagus nerve and prevertebral ganglia in healthy subjects. However, studies have shown that the system is operable with a severed vagus nerve. The neurons of the enteric nervous system control the motor functions of the system, in addition to the secretion of gastrointestinal enzymes. These neurons communicate through many neurotransmitters similar to the CNS, including acetylcholine, dopamine, and serotonin. The large presence of serotonin and dopamine in the intest ...
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Chyme
Chyme or chymus (; ) is the semi-fluid mass of partly digested food that is expelled by the stomach, through the pyloric valve, into the duodenum (the beginning of the small intestine). Chyme results from the mechanical and chemical breakdown of a bolus and consists of partially digested food, water, hydrochloric acid, and various digestive enzymes. Chyme slowly passes through the pyloric sphincter and into the duodenum, where the extraction of nutrients begins. Depending on the quantity and contents of the meal, the stomach will digest the food into chyme in some time from 40 minutes to 3 hours. With a pH of approximately 2, chyme emerging from the stomach is very acidic. The duodenum secretes a hormone, cholecystokinin (CCK), which causes the gall bladder to contract, releasing alkaline bile into the duodenum. CCK also causes the release of digestive enzymes from the pancreas. The duodenum is a short section of the small intestine located between the stomach and the re ...
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Peristalsis
Peristalsis ( , ) is a type of intestinal motility, characterized by symmetry in biology#Radial symmetry, radially symmetrical contraction and relaxation of muscles that propagate in a wave down a tube, in an wikt:anterograde, anterograde direction. Peristalsis is progression of coordinated contraction of involuntary circular muscles, which is preceded by a simultaneous contraction of the longitudinal muscle and relaxation of the circular muscle in the lining of the gut. In much of a digestive tract, such as the human gastrointestinal tract, smooth muscle tissue contracts in sequence to produce a peristaltic wave, which propels a ball of food (called a bolus (digestion), bolus before being transformed into chyme in the stomach) along the tract. The peristaltic movement comprises relaxation of circular smooth muscles, then their contraction behind the chewed material to keep it from moving backward, then longitudinal contraction to push it forward. Earthworms use a similar mec ...
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Circular Folds
The circular folds (also known as valves of Kerckring, valves of Kerchkring, plicae circulares, ''plicae circulae'', and ''valvulae conniventes'') are large valvular flaps projecting into the lumen of the small intestine. Structure The entire small intestine has circular folds of mucous membrane. The majority extend transversely around the cylinder of the small intestine, for about one-half or two-thirds of its circumference. Some form complete circles. Others have a spiral direction. The latter usually extend a little more than once around the bowel, but occasionally two or three times. While the larger folds are about 1 cm in depth at their broadest part, most folds are smaller. There tends to be an alternating pattern between larger and smaller folds. Distribution They are not found at the commencement of the duodenum, but begin to appear about 2.5 or 5 cm beyond the pylorus. In the lower part of the descending portion, below the point where the bile and pancre ...
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Small Intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about long and folds many times to fit in the abdomen. Although it is longer than the large intestine, it is called the small intestine because it is narrower in diameter. The small intestine has three distinct regions – the duodenum, jejunum, and ileum. The duodenum, the shortest, is where preparation for absorption through small finger-like protrusions called intestinal villus, intestinal villi begins. The jejunum is specialized for the absorption through its lining by enterocytes: small nutrient particles which have been previously digested by enzymes in the duodenum. The main function of the ileum is to absorb vitami ...
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Abdominal X-ray
An abdominal x-ray is an x-ray of the abdomen. It is sometimes abbreviated to AXR, or KUB (for kidneys, ureters, and urinary bladder). Indications In adults, abdominal X-rays have a very low specificity and cannot rule out suspected obstruction, injury or disease reliably. CT scan provides an overall better diagnosis, allows surgical strategy planning, and possibly fewer unnecessary laparotomies. Abdominal x-ray is therefore not recommended for adults with acute abdominal pain presenting in the emergency department. In children, abdominal x-ray is indicated in the acute setting: *Suspected bowel obstruction or gastrointestinal perforation; Abdominal x-ray will demonstrate most cases of bowel obstruction, by showing dilated bowel loops. * Foreign body in the alimentary tract; can be identified if it is radiodense. *Suspected abdominal mass *In suspected intussusception, an abdominal x-ray does not exclude intussusception but is useful in the differential diagnosis to exclu ...
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Ulcerative Colitis
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. It is a long-term condition that results in inflammation and ulcers of the colon and rectum. The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood ( hematochezia). Weight loss, fever, and anemia may also occur. Often, symptoms come on slowly and can range from mild to severe. Symptoms typically occur intermittently with periods of no symptoms between flares. Complications may include abnormal dilation of the colon ( megacolon), inflammation of the eye, joints, or liver, and colon cancer. The cause of UC is unknown. Theories involve immune system dysfunction, genetics, changes in the normal gut bacteria, and environmental factors. Rates tend to be higher in the developed world with some proposing this to be the result of less exposure to intestinal infections, or to a Western diet and lifestyle. The remova ...
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Volvulus
A volvulus is when a loop of intestine twists around itself and the mesentery that supports it, resulting in a bowel obstruction. Symptoms include abdominal pain, abdominal bloating, vomiting, constipation, and bloody stool. Onset of symptoms may be rapid or more gradual. The mesentery may become so tightly twisted that blood flow to part of the intestine is cut off, resulting in ischemic bowel. In this situation there may be fever or significant pain when the abdomen is touched. Risk factors include a birth defect known as intestinal malrotation, an enlarged colon, Hirschsprung disease, pregnancy, and abdominal adhesions. Long term constipation and a high fiber diet may also increase the risk. The most commonly affected part of the intestines in adults is the sigmoid colon, with the cecum being the second most affected. In children the small intestine is more often involved. The stomach can also be affected. Diagnosis is typically with medical imaging such as ...
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Sigmoidal Volvolus
Sigmoid colon volvulus, also known as sigmoid volvulus, is volvulus affecting the sigmoid colon. It is a common cause of bowel obstruction and constipation. It is common in Asia, India (7% of intestinal obstruction) and especially South India because of the high fibre diet. It is a very common cause of large bowel obstruction in Peru and Bolivia due to high altitude. Signs and symptoms * Pain in abdomen – initially left-sided, eventually all over * Absolute constipation * Enormous distension of abdomen * Late vomiting and eventually dehydration * Features of peritonitis * Hiccup and retching may occur * Tyre-like feel of the abdomen is diagnostic Cause The condition is more common in males and with old age. It is also common in people with chronic constipation and laxative abuse. It is common in: * Ogilvie syndrome * Individuals with learning difficulties * Chagas disease * Hypothyroidism * Anticholinergic drugs * Multiple sclerosis * Scleroderma * Parkinson's disease In si ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ...
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