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Glycerophosphate
Glycerophosphate may refer to: * Glycerol 1-phosphate * Glycerol 2-phosphate (BGP) * Glycerol 3-phosphate ''sn''-Glycerol 3-phosphate is the organic ion with the formula HOCH2CH(OH)CH2OPO32-. It is one of two stereoisomers of the ester of dibasic phosphoric acid (HOPO32-) and glycerol. It is a component of bacterial and eukaryotic glycerophospholi ... {{Short pages monitor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycerol 1-phosphate
''sn''-Glycerol 1-phosphate is the conjugate base of a phosphoric ester of glycerol. It is a component of ether lipids, which are common for archaea. Biosynthesis and metabolism Glycerol 1-phosphate is synthesized by reducing dihydroxyacetone phosphate (DHAP), a glycolysis intermediate, with sn-glycerol-1-phosphate dehydrogenase, ''sn''-glycerol-1-phosphate dehydrogenase. DHAP and thus glycerol 1-phosphate is also possible to be synthesized from amino acids and citric acid cycle intermediates via glyconeogenesis, gluconeogenesis pathway. : + NAD(P)H + H+ → + NAD(P)+ Glycerol 1-phosphate is a starting material for ''de novo'' synthesis of ether lipids, such as those derived from archaeol and caldarchaeol. It is first geranylgeranylated on its ''sn''-3 position by a cytosolic enzyme, phosphoglycerol geranylgeranyltransferase. A second geranylgeranyl group is then added on the ''sn''-2 position making unsaturated archaetidic acid. Lipid divide Organisms other than archaea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycerol 2-phosphate
Glycerol 2-phosphate is the conjugate base of phosphoric ester of glycerol. It is commonly known as β-glycerophosphate or BGP. Unlike glycerol 1-phosphate and glycerol 3-phosphate, this isomer is not chiral. It is also less common. Applications β-Glycerophosphate is an inhibitor of the enzyme serine/threonine phosphatase. It is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. Although previously presumed to be non-transportable and reliant on extracellular phosphatases such as alkaline phosphatase (PhoA) for utilization, recent research indicates that ''Escherichia coli'' can use β-Glycerophosphate as a sole phosphorus source in the absence of PhoA, relying on the Ugp transporter system encoded by the ugpBAECQ operon. β-Glycerophosphate is also used to drive osteogenic differentiation of bone marrow stem cells ''in vitro''. β-Glycerophosphate is used to buffer M17 media for ''Lactococcus'' culture Culture ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
