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Ganglion Mother Cell
Ganglion mother cells (GMCs) are cells involved in neurogenesis, in non-mammals, that divide only once to give rise to two neurons, or one neuron and one glial cell or two glial cells, and are present only in the central nervous system. They are also responsible for transcription factor expression. While each ganglion mother cell necessarily gives rise to two neurons, a neuroblast can asymmetric cell division, asymmetrically divide multiple times.Doe, C. Q. et al (2008). Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells. {{PMC, 2804867. GMCs are the progeny of type I neuroblasts. Neuroblasts asymmetrically divide during embryogenesis to create GMCs.Doe, C. Q. (1992). Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system. Development, 116(4), 855-863. GMCs are only present in certain species and only during the embryonic and larval stages of life. Recent research has sh ...
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Neuroblast Cell Division - 486169
In vertebrates, a neuroblast or primitive nerve cell is a G0 phase, postmitotic cell that does not divide further, and which will develop into a neuron after a Cell migration, migration phase. In invertebrates such as ''Drosophila,'' neuroblasts are neural progenitor cells which divide asymmetrically to produce a neuroblast, and a daughter cell of varying potency depending on the type of neuroblast. Vertebrate neuroblasts Cellular differentiation, differentiate from radial glial cells and are committed to becoming neurons. Neural stem cells, which only divide symmetrically to produce more neural stem cells, transition gradually into radial glial cells. Radial glial cells, also called radial glial progenitor cells, divide Asymmetric cell division, asymmetrically to produce a neuroblast and another radial glial cell that will re-enter the cell cycle. This mitosis occurs in the germinal neuroepithelial cell, neuroepithelium (or germinal zone), when a radial glial cell divides to produc ...
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Neural Stem Cell
Neural stem cells (NSCs) are self-renewing, multipotent cells that firstly generate the radial glial progenitor cells that generate the neurons and glia of the nervous system of all animals during embryonic development. Some neural progenitor stem cells persist in highly restricted regions in the adult vertebrate brain and continue to produce neurons throughout life. Differences in the size of the central nervous system are among the most important distinctions between the species and thus mutations in the genes that regulate the size of the neural stem cell compartment are among the most important drivers of vertebrate evolution. Stem cells are characterized by their capacity to differentiate into multiple cell types. They undergo symmetric or asymmetric cell division into two daughter cells. In symmetric cell division, both daughter cells are also stem cells. In asymmetric division, a stem cell produces one stem cell and one specialized cell. NSCs primarily differentiate ...
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Drosophila Connectome
A ''Drosophila'' connectome is a list of neurons in the ''Drosophila melanogaster'' (fruit fly) nervous system, and the chemical synapses between them. The fly's central nervous system consists of the brain plus the ventral nerve cord, and both are known to differ considerably between male and female. Dense connectomes have been completed for the female adult brain, the male and female nerve cords, and the female larval stage. The available connectomes show only chemical synapses - other forms of inter-neuron communication such as gap junctions or neuromodulators are not represented. ''Drosophila'' is the most complex creature with a connectome, which had only been previously obtained for three other simpler organisms, first '' C. elegans''. The connectomes have been obtained by the methods of neural circuit reconstruction, which over the course of many years worked up through various subsets of the fly brain to current efforts aimed at a unified central brain and VNC connectome, fo ...
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Associative Learning
Learning is the process of acquiring new understanding, knowledge, behaviors, skills, values, attitudes, and preferences. The ability to learn is possessed by humans, non-human animals, and some machines; there is also evidence for some kind of learning in certain plants. Some learning is immediate, induced by a single event (e.g. being burned by a hot stove), but much skill and knowledge accumulate from repeated experiences. The changes induced by learning often last a lifetime, and it is hard to distinguish learned material that seems to be "lost" from that which cannot be retrieved. Human learning starts at birth (it might even start before) and continues until death as a consequence of ongoing interactions between people and their environment. The nature and processes involved in learning are studied in many established fields (including educational psychology, neuropsychology, experimental psychology, cognitive sciences, and pedagogy), as well as emerging fields of kn ...
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Mushroom Bodies
The mushroom bodies or ''corpora pedunculata'' are a pair of structures in the Supraesophageal ganglion, brain of arthropods, including insects and Crustacean, crustaceans, and some annelids (notably the ragworm ''Platynereis dumerilii''). They are known to play a role in olfactory memory, olfactory learning and memory. In most insects, the mushroom bodies and the lateral horn of insect brain, lateral horn are the two higher brain regions that receive olfactory information from the antennal lobe via projection neurons. They were first identified and described by French biologist Félix Dujardin in 1850. Structure Mushroom bodies are usually described as neuropils, i.e., as dense networks of neuronal processes (dendrite and axon terminals) and glia. They get their name from their roughly hemispherical ''calyx'', a protuberance that is joined to the rest of the brain by a central nerve tract or ''peduncle''. Most of our current knowledge of mushroom bodies comes from studies of a f ...
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Central Complex
Central is an adjective usually referring to being in the center (other), center of some place or (mathematical) object. Central may also refer to: Directions and generalised locations * Central Africa, a region in the centre of Africa continent, also known as Middle Africa * Central America, a region in the centre of America continent * Central Asia, a region in the centre of Eurasian continent * Central Australia, a region of the Australian continent * Central Belt, an area in the centre of Scotland * Central Europe, a region of the European continent * Central London, the centre of London * Central Region (other) * Central United States, a region of the United States of America Specific locations Countries * Central African Republic, a country in Africa States and provinces * Blue Nile (state) or Central, a state in Sudan * Central Department, Paraguay * Central Province (Kenya) * Central Province (Papua New Guinea) * Central Province (Solomon Islands) * Ce ...
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Insect Brain
The supraesophageal ganglion (also "supraoesophageal ganglion", "arthropod brain" or "microbrain") is the first part of the arthropod, especially insect, central nervous system. It receives and processes information from the first, second, and third Metamerism (biology), metameres. The supraesophageal ganglion lies Dorsum (anatomy), dorsal to the esophagus and consists of three parts, each a pair of ganglia that may be more or less pronounced, reduced, or fused depending on the genus (biology), genus: * The ''protocerebrum'', associated with the arthropod eye, eyes (Eye#Compound eyes, compound eyes and ocelli). Directly associated with the eyes is the optic lobe (arthropod), optic lobe, as the visual center of the brain. * The ''deutocerebrum'' processes sensory information from the Antenna (biology), antennae. It consists of two parts, the antennal lobe and the dorsal lobe. The dorsal lobe also contains motor neurons which control the antennal muscles. * The ''tritocerebrum'' i ...
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Embryonic Development
In developmental biology, animal embryonic development, also known as animal embryogenesis, is the developmental stage of an animal embryo. Embryonic development starts with the fertilization of an egg cell (ovum) by a sperm, sperm cell (spermatozoon). Once fertilized, the ovum becomes a single diploid cell known as a zygote. The zygote undergoes mitosis, mitotic cell division, divisions with no significant growth (a process known as cleavage (embryo), cleavage) and cellular differentiation, leading to development of a multicellular embryo after passing through an organizational checkpoint during mid-embryogenesis. In mammals, the term refers chiefly to the early stages of prenatal development, whereas the terms fetus and fetal development describe later stages. The main stages of animal embryonic development are as follows: * The zygote undergoes a series of cell divisions (called cleavage) to form a structure called a morula. * The morula develops into a structure called a bla ...
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Neurogenesis In Optic Lobe Development - 486169
Neurogenesis is the process by which nervous system cells, the neurons, are produced by neural stem cells (NSCs). This occurs in all species of animals except the porifera (sponges) and placozoans. Types of NSCs include neuroepithelial cells (NECs), radial glial cells (RGCs), basal progenitors (BPs), intermediate neuronal precursors (INPs), subventricular zone astrocytes, and subgranular zone radial astrocytes, among others. Neurogenesis is most active during embryonic development and is responsible for producing all the various types of neurons of the organism, but it continues throughout adult life in a variety of organisms. Once born, neurons do not divide (see mitosis), and many will live the lifespan of the animal, except under extraordinary and usually pathogenic circumstances. In mammals Developmental neurogenesis During embryonic development, the mammalian central nervous system (CNS; brain and spinal cord) is derived from the neural tube, which contains NSCs that wi ...
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Motor Neuron
A motor neuron (or motoneuron), also known as efferent neuron is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. There are two types of motor neuron – upper motor neurons and lower motor neurons. Axons from upper motor neurons synapse onto interneurons in the spinal cord and occasionally directly onto lower motor neurons. The axons from the lower motor neurons are efferent nerve fibers that carry signals from the spinal cord to the effectors. Types of lower motor neurons are alpha motor neurons, beta motor neurons, and gamma motor neurons. A single motor neuron may innervate many muscle fibres and a muscle fibre can undergo many action potentials in the time taken for a single muscle twitch. Innervation takes place at a neuromuscular junction and twitches can become superimpo ...
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Interneurons
Interneurons (also called internuncial neurons, association neurons, connector neurons, or intermediate neurons) are neurons that are not specifically motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits, enabling communication between sensory or motor neurons and the central nervous system (CNS). They play vital roles in reflexes, neuronal oscillations, and neurogenesis in the adult mammalian brain. Interneurons can be further broken down into two groups: local interneurons and relay interneurons. Local interneurons have short axons and form circuits with nearby neurons to analyze small pieces of information. Relay interneurons have long axons and connect circuits of neurons in one region of the brain with those in other regions. However, interneurons are generally considered to operate mainly within local brain areas. The interaction between interneurons allows the brain to perform complex functions such as learning and decision-making. S ...
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