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Fucitol
Fucitol, also known as L-fucitol, 1-deoxy-L-galactitol, and (2''R'',3''S'',4''R'',5''S'')-hexane-1,2,3,4,5-pentol, is a sugar alcohol derived from fucoidan which is found in the North Atlantic seaweed ''Fucus vesiculosus'' or by the reduction of fucose. See also * Galactitol Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose. It has a slightly sweet taste. In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens of the eye leading to cataracts. Gal ... References External links * Sugar alcohols {{Alcohol-stub ...
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Sugar Alcohol
Sugar alcohols (also called polyhydric alcohols, polyalcohols, alditols or glycitols) are organic compounds, typically derived from sugars, containing one hydroxyl group attached to each carbon atom. They are white, water-soluble solids that can occur naturally or be produced industrially by hydrogenating sugars. Since they contain multiple groups, they are classified as polyols. Sugar alcohols are used widely in the food industry as thickeners and sweeteners. In commercial foodstuffs, sugar alcohols are commonly used in place of table sugar (sucrose), often in combination with high-intensity artificial sweeteners, in order to offset their low sweetness. Xylitol and sorbitol are popular sugar alcohols in commercial foods. Structure Sugar alcohols have the general formula . In contrast, sugars have two fewer hydrogen atoms, for example, or . Like their parent sugars, sugar alcohols exist in diverse chain length. Most have five- or six-carbon chains, because they are deriv ...
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Fucose
Fucose is a hexose deoxy sugar with the chemical formula C6H12O5. It is found on ''N''-linked glycans on the mammalian, insect and plant cell surface. Fucose is the fundamental sub-unit of the seaweed polysaccharide fucoidan. The α(1→3) linked core of fucoidan is a suspected carbohydrate antigen for IgE-mediated allergy. Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a hydroxyl group on the carbon at the 6-position (C-6) (thereby making it a deoxy sugar) and the L -configuration. It is equivalent to 6-deoxy--galactose. In the fucose-containing glycan structures, fucosylated glycans, fucose can exist as a terminal modification or serve as an attachment point for adding other sugars. In human ''N''-linked glycans, fucose is most commonly linked α-1,6 to the reducing terminal β-''N''-acetylglucosamine. However, fucose at the non-reducing termini linked α-1,2 to galactose forms the H antigen, the substructure o ...
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Fucoidan
Fucoidan is a long chain sulfated polysaccharide found in various species of brown algae. Commercially available fucoidan is commonly extracted from the seaweed species ''Fucus vesiculosus'' (Wrack (seaweed), wracks), ''Cladosiphon okamuranus'', ''Laminaria japonica'' (''kombu'', sugar kelp) and ''Undaria pinnatifida'' (''wakame''). Variant forms of fucoidan have also been found in animal species, including the sea cucumber. Fucoidan occurs in the cell walls of the seaweed plant and serves to protect it from external stresses. The same protective benefits that are of value to the seaweed plant have also found to be of potential benefit for both human and animal health. Fucoidan extracts are utilised in a range of therapeutic health care preparations, being incorporated as high value ingredients in nutritional, medical device, skincare and dermatological products. The bioactivity of fucoidan extracts is largely determined by the fucoidan extraction method and the seaweed species fro ...
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North Atlantic
The Atlantic Ocean is the second largest of the world's five oceanic divisions, with an area of about . It covers approximately 17% of Earth's surface and about 24% of its water surface area. During the Age of Discovery, it was known for separating the New World of the Americas (North America and South America) from the Old World of Afro-Eurasia (Africa, Asia, and Europe). Through its separation of Afro-Eurasia from the Americas, the Atlantic Ocean has played a central role in the development of human society, globalization, and the histories of many nations. While the Norse were the first known humans to cross the Atlantic, it was the expedition of Christopher Columbus in 1492 that proved to be the most consequential. Columbus's expedition ushered in an age of exploration and colonization of the Americas by European powers, most notably Portugal, Spain, France, and the United Kingdom. From the 16th to 19th centuries, the Atlantic Ocean was the center of both an epo ...
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Seaweed
Seaweed, or macroalgae, refers to thousands of species of macroscopic, multicellular, marine algae. The term includes some types of ''Rhodophyta'' (red), '' Phaeophyta'' (brown) and ''Chlorophyta'' (green) macroalgae. Seaweed species such as kelps provide essential nursery habitat for fisheries and other marine species and thus protect food sources; other species, such as planktonic algae, play a vital role in capturing carbon and producing at least 50% of Earth's oxygen. Natural seaweed ecosystems are sometimes under threat from human activity. For example, mechanical dredging of kelp destroys the resource and dependent fisheries. Other forces also threaten some seaweed ecosystems; for example, a wasting disease in predators of purple urchins has led to an urchin population surge which has destroyed large kelp forest regions off the coast of California. Humans have a long history of cultivating seaweeds for their uses. In recent years, seaweed farming has become a global ...
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Fucus Vesiculosus
''Fucus vesiculosus'', known by the common names bladderwrack, black tang, rockweed, sea grapes, bladder fucus, sea oak, cut weed, dyers fucus, red fucus and rock wrack, is a seaweed found on the coasts of the North Sea, the western Baltic Sea and the Atlantic and Pacific Oceans. It was the original source of iodine, discovered in 1811, and was used extensively to treat goitre. Description The fronds of ''F. vesiculosus'' grow to long and wide and have a prominent midrib throughout. It is attached by a basal disc-shaped holdfast. It has almost spherical air bladders, which are usually paired one on either side of the mid-rib but may be absent in young plants. The margin is smooth and the frond is dichotomously branched. It is sometimes confused with '' Fucus spiralis'' with which it hybridises and is similar to ''Fucus serratus''. Biology Plants of ''F. vesiculosus'' are dioecious. Gametes are generally released into the seawater under calm conditions, and the eggs are fer ...
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Galactitol
Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose. It has a slightly sweet taste. In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens of the eye leading to cataracts. Galactitol is produced from galactose in a reaction catalyzed by aldose reductase. The other common galactose metabolism defect is a defect in galactose-1-phosphate uridylyltransferase Galactose-1-phosphate uridyltransferase (or GALT, G1PUT) is an enzyme () responsible for converting ingested galactose to glucose. Galactose-1-phosphate uridyltransferase (GALT) catalyzes the second step of the Leloir pathway of galactose meta ..., an autosomal recessive disorder, which also causes a buildup of galactitol as a result of increased concentrations of galactose-1-phosphate and galactose. This disorder leads to cataracts caused by galactitol buildup. References External links * {{Fructose and galactose metabolic intermediates Sugar a ...
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