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Flubendazole
Flubendazole is an anthelmintic, used both in humans and for veterinarian purposes. It is very close chemically to mebendazole, the only difference being an added fluorine atom. __TOC__ Human use It is available for human use to treat worm infections. In certain countries such as France, it is inexpensive and available OTC (without prescription) under the brand name Fluvermal as an alternative to mebendazole which is not currently sold there. Veterinarian use Under veterinary use, its brand name is Flutelmium which is a paste manufactured by Janssen Pharmaceutica N.V. used by veterinarians for protection against internal parasites and worms in dogs and cats. Other brand names are Flubenol, Biovermin, and Flumoxal. Since 2000, Flubendazole-treated grit has increasingly been laid out on a landscape-scale across many UK Red grouse, grouse-shooting moors by gamekeepers in an attempt to reduce the impact on bird numbers from Trichostrongylus tenuis, strongyle worm. Evidence of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzimidazoles
Benzimidazole is a heterocyclic aromatic organic compound. This bicyclic compound may be viewed as fused rings of the aromatic compounds benzene and imidazole. It is a white solid that appears in form of tabular crystals. Preparation Benzimidazole was discovered during research on vitamin B12. The benzimidazole nucleus was found to be a stable platform on which drugs could be developed. Benzimidazole is produced by condensation of o-phenylenediamine with formic acid, or the equivalent trimethyl orthoformate: :C6H4(NH2)2 + HC(OCH3)3 → C6H4N(NH)CH + 3 CH3OH 2-Substituted derivatives are obtained when the condensation is conducted with aldehydes in place of formic acid, followed by oxidation. Reactions Benzimidazole is a base: :C6H4N(NH)CH + H+ → 6H4(NH)2CHsup>+ It can also be deprotonated with stronger bases: :C6H4N(NH)CH + LiH → Li 6H4N2CH + H2 The imine can be alkylated and also serves as a ligand in coordination chemistry. The most pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthelmintic
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals, particularly small ruminants such as goats and sheep. Anthelmintic medication is also used in mass deworming campaigns of school-aged children in many developing countries. Anthelmintics are also used for mass deworming of livestock. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Many early treatments were herbal, such as the oil of herbs of the genus '' Chenopodium'' that were given as anthelmintic treatment for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mebendazole
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. It has been used for treatment of giardiasis but is not a preferred agent. It is taken by mouth. Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type. Mebendazole came into use in 1971, after it was developed by Janssen Pharmaceutica in Belgium. It is on the World Health Organization's List of Essential Medicines. Mebendazole is available as a generic medication. Medical use Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nema ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Janssen Pharmaceutica
Johnson & Johnson Innovative Medicine (formerly Janssen Pharmaceuticals) is a Belgian pharmaceutical company headquartered in Beerse, Belgium, and wholly owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Pharmaceuticals was purchased by New Jersey–based American corporation Johnson & Johnson, and became part of Johnson & Johnson Pharmaceutical Research and Development (J&J PRD), later renamed to Janssen Research and Development, LLC (JRD), which conducts research and development activities related to a wide range of human medical disorders, including mental illness, neurological disorders, anesthesia and Analgesic, analgesia, gastrointestinal disorders, fungal infection, HIV/AIDS, Allergy, allergies and cancer. Janssen and Ortho-McNeil Pharmaceutical have been placed in the Ortho-McNeil-Janssen group within Johnson & Johnson Company. Subsidiaries * Actelion * Cilag, Cilag AG * Janssen Biotech (formerly ''Centocor'') * Janssen Vaccines (f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Veterinarian
A veterinarian (vet) or veterinary surgeon is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, veterinarians also play a role in animal reproduction, health management, Animal Conservation, conservation, husbandry and breeding and preventive medicine like animal nutrition, nutrition, vaccination and parasitic control as well as biosecurity and zoonotic disease surveillance and prevention. Description In many countries, the local nomenclature for a veterinarian is a regulated and protected term, meaning that members of the public without the prerequisite qualifications and/or license are not able to use the title. This title is selective in order to produce the most knowledgeable veterinarians that pass these qualifications. In many cases, the activities that may be undertaken by a veterinarian (such as treatment of illness or surgery in animals) are restricted only to thos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parasite
Parasitism is a Symbiosis, close relationship between species, where one organism, the parasite, lives (at least some of the time) on or inside another organism, the Host (biology), host, causing it some harm, and is Adaptation, adapted structurally to this way of life. The entomologist E. O. Wilson characterised parasites' way of feeding as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as Armillaria mellea, honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the Orobanchaceae, broomrapes. There are six major parasitic Behavioral ecology#Evolutionarily stable strategy, strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), wikt:trophic, trophicallytransmitted parasitism (by being eaten), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Red Grouse
The red grouse (''Lagopus scotica'') is a medium-sized bird of the grouse family which is found in Calluna, heather moorland in Great Britain and Ireland. It was formerly classified as a subspecies of the willow ptarmigan (''Lagopus lagopus'') but is now considered to be a separate species. It is also known as the moorcock, moorfowl or moorbird. ''Lagopus'' is derived from Ancient Greek (), meaning "hare", + (), "foot", in reference to the feathered feet and toes typical of this cold-adapted genus, and ''scotica'' means "of Scotland". The red grouse is the logo of The Famous Grouse whisky and an animated bird is a character in a series of its advertisements. The red grouse is also the emblem of the journal ''British Birds (magazine), British Birds''. Description The red grouse is distinguished from the willow ptarmigan and rock ptarmigan by its reddish brown plumage, rather than the white winter plumage. The tail is black and the legs are white. There are white stripes on t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamekeeper
In the United Kingdom, a gamekeeper (often abbreviated to keeper) is a person who manages an area of countryside (e.g., areas of woodland, moorland, waterway or farmland) to make sure that there is enough Game (hunting), game for hunting, or fish for fishing, and acts as guide to those pursuing them. Description Typically, a gamekeeper is employed by a landowner or by a country Estate (house), estate, to prevent poaching, to rear and release game birds such as common pheasants and French partridge, eradicate pests, encourage and manage wild red grouse, and to control predators such as weasels, to manage habitats to suit game, and to monitor the health of the game. Today, some three thousand full-time gamekeepers are employed in the UK, compared to as many as 25,000 at the beginning of the 20th century. In addition, there are many people who spend their leisure time and money rearing game and maintaining habitats on their own small shoots. There are several variations in gameke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trichostrongylus Tenuis
''Trichostrongylus tenuis'', also known as the strongyle worm, is a gut nematode found in the United Kingdom, sensitive to Pyrantel pamoate. Larvae have a short migration inside the mucosa of the intestine and return quickly to the digestive tract. This endoparasite causes a condition often called strongylosis or 'grouse disease' and which can be the cause of regular crashes in grouse populations. When the adult worm burrows into the caeca walls it causes a lot of damage and internal bleeding which in itself is harmful to the grouse. The worms ultimately reduce the digestive efficiency thus affecting the condition of the grouse. The eggs of the strongyle worm found in the caecal droppings of red grouse, hatch out into a microscopic larvae stage. Living within the dropping they feed off bacteria and organic matter they develop through two moult In biology, moulting (British English), or molting (American English), also known as sloughing, shedding, or in many invertebrates, ec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Manure
Manure is organic matter that is used as organic fertilizer in agriculture. Most manure consists of animal feces; other sources include compost and green manure. Manures contribute to the fertility of soil by adding organic matter and nutrients, such as nitrogen, that are utilised by bacteria, fungi, and other organisms in the soil. Higher organisms then feed on the fungi and bacteria in a chain of life that comprises the soil food web. Types There are in the 21st century three main classes of manures used in soil management: Animal manure Most animal manure consists of feces. Common forms of animal manure include farmyard manure (or farm slurry ( liquid manure). Farmyard manure also contains plant material (often straw), which has been used as bedding for animals and has absorbed the feces and urine. Agricultural manure in liquid form, known as slurry, is produced by more intensive livestock rearing systems where concrete or slats are used instead of straw bedding. M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthelmintics
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms ( helminths) and other internal parasites from the body by either stunning or killing them without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals, particularly small ruminants such as goats and sheep. Anthelmintic medication is also used in mass deworming campaigns of school-aged children in many developing countries. Anthelmintics are also used for mass deworming of livestock. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Many early treatments were herbal, such as the oil of herbs of the genus '' Chenopodium'' that were given as anthelmintic treatment ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antiparasitic Agents
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others. Antiparasitics target the parasitic agents of the infections by destroying them or inhibiting their growth; they are usually effective against a limited number of parasites within a particular class. Antiparasitics are one of the antimicrobial drugs which include antibiotics that target bacteria, and antifungals that target fungi. They may be administered orally, intravenously or topically. Overuse or misuse of antiparasitics can lead to the development of antimicrobial resistance. Broad-spectrum antiparasitics, analogous to broad-spectrum antibiotics for bacteria, are antiparasitic drugs with efficacy in treating a wide range of parasitic infections caused by parasites from different classes. Types Broad-spectrum * Nitazoxanide Antiprotozoals * Melarsoprol (for treatment ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
