|
Festuclavine
Festuclavine is an ergoline Ergoline is a core structure in many alkaloids and their synthetic derivatives. Ergoline alkaloids were first characterized in ergot. Some of these are implicated in the condition of ergotism, which can take a convulsive form or a gangrenous for ... fungal isolate. See also * Festuclavine dehydrogenase Notes Ergolines Alkaloids found in fungi Ergot alkaloids {{Alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Festuclavine Dehydrogenase
Festuclavine dehydrogenase (, ''FgaFS'', ''festuclavine synthase'') is an enzyme with systematic name ''festuclavine:NAD+ oxidoreductase''. This enzyme catalyses the following chemical reaction : festuclavine + NAD+ \rightleftharpoons 6,8-dimethyl-6,7-didehydroergoline + NADH + H+ The enzyme takes part in the biosynthesis of fumigaclavine C Fumigaclavine C is an ergoline alkaloid produced by ''Aspergillus fumigatus''. Both 8α and 8β diastereomers (epimers) were named fumigaclavine C in scientific literature. See also * 9-Deacetoxyfumigaclavine C * Fumigaclavine A * Fumigaclavine .... References External links * {{Portal bar, Biology, border=no EC 1.5.1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ergoline
Ergoline is a core structure in many alkaloids and their synthetic derivatives. Ergoline alkaloids were first characterized in ergot. Some of these are implicated in the condition of ergotism, which can take a convulsive form or a gangrenous form. Even so, many ergoline alkaloids have been found to be clinically useful. Annual world production of ergot alkaloids has been estimated at 5,000–8,000 kg of all ergopeptines and 10,000–15,000 kg of lysergic acid, used primarily in the manufacture of semi-synthetic derivatives. Others, such as lysergic acid diethylamide, better known as LSD, a Semisynthesis, semi-synthetic derivative, and ergine, a natural derivative found in ''Argyreia nervosa'', ''Ipomoea tricolor'' and related species, are known Psychedelic drug, psychedelic substances. Natural occurrence Ergoline alkaloids are found in fungi such as Claviceps purpurea, Claviceps paspali, and the related Periglandula, which have a permanent, symbiotic bond with numerous ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloids Found In Fungi
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
