Exploding Head Syndrome
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Exploding Head Syndrome
Exploding head syndrome (EHS) is an abnormal sensory perception during sleep in which a person experiences auditory hallucinations that are loud and of short duration when falling asleep or waking up. The noise may be frightening, typically occurs only occasionally, and is not a serious health concern. People may also experience a flash of light. Pain is typically absent. The cause is unknown. Potential organic explanations that have been investigated but ruled out include ear problems, temporal lobe seizure, nerve dysfunction, or specific genetic changes. Potential risk factors include psychological stress. It is classified as a sleep disorder or headache disorder. People often go undiagnosed. There is no high-quality evidence to support treatment. Reassurance may be sufficient. Clomipramine and calcium channel blockers have been tried. While the frequency of the condition is not well studied, some have estimated that it occurs in about 10% of people. Women are reportedly ...
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The Telescopes
The Telescopes are an English noise, space rock, dream pop and psychedelic band formed in 1987 by artist, composer, and musician Stephen Lawrie, with band members David Fitzgerald and Joanna Doran joining later. The band's line-up is in constant flux; there can be anywhere between 1 and 20 members on a recording. Some of the initial influences on Lawrie as a songwriter were The Beatles, Bob Dylan, David Bowie, Neil Young, Einstürzende Neubauten, Can, Faust, Lydia Lunch, Sonic Youth and Sun Ra. By the time The Telescopes were formed, influences were drawn from artists such as The Velvet Underground, Suicide, The Stooges and The 13th Floor Elevators. The Telescopes have influenced the shoegaze, space rock and neo-psychedelic movement including artists such as The Brian Jonestown Massacre, Black Rebel Motorcycle Club, Füxa, The Warlocks, Revolver, Whipping Boy, Vanishing Lines, Seefeel, Ecstasy of Saint Theresa, Frances Bean Cobain, Portishead, Mogwai and Radioh ...
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Clomipramine
Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, body dysmorphic disorder and chronic pain. It has also been notably used to treat premature ejaculation and the cataplexy associated with narcolepsy. It may also address certain fundamental features surrounding narcolepsy besides cataplexy (especially hypnagogic and hypnopompic hallucinations). The evidence behind this, however, is less robust. As with other antidepressants (notably including selective serotonin reuptake inhibitors), it may paradoxically increase the risk of suicide in those under the age of 25, at least in the first few weeks of treatment. It is typically taken by mouth, although intravenous preparations are sometimes used. Common side effects includ ...
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Calcium Channel
A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, which are a type of calcium channel regulated by changes in membrane potential. Some calcium channels are regulated by the binding of a ligand.Striggow F, Ehrlich BE (August 1996). "Ligand-gated calcium channels inside and out". ''Current Opinion in Cell Biology''. 8 (4): 490–495. Doi (identifier), doi:doi:10.1016/S0955-0674(96)80025-1, 10.1016/S0955-0674(96)80025-1. PMID (identifier), PMID]8791458 Other calcium channels can also be regulated by both voltage and ligands to provide precise control over ion flow. Some cation channels allow calcium as well as other cations to pass through the membrane. Calcium channels can participate in the creation of Action potential, action potentials across cell membranes. Calcium channels can also be used to release calcium ions as Second messenger system, second messengers within the cell, affec ...
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Antidepressant Discontinuation Syndrome
Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, akathisia, intrusive thoughts, depersonalization and derealization, mania, anxiety, and depression. The problem usually begins within three days and may last for several weeks or months. Psychosis may rarely occur. A discontinuation syndrome can occur after stopping any antidepressant including selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), monoamine oxidase inhibitors (MAOIs), and tricyclic antidepressants (TCAs). The risk is greater among those who have taken the medication for longer and when the medication in question has a short half-life. The underlying reaso ...
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Delta Sleep
Delta Sleep are a British math rock band, formed in 2010 in Canterbury. They are currently based in Brighton and consist of Devin Yüceil on guitar and vocals, Glen Hodgson on guitar, Dave Jackson on bass and Blake Mostyn on drums. They have so far released 4 EPs and 5 albums. History Early years, ''Management'', and ''Twin Galaxies'' (2010-2017) Delta Sleep emerged from a band called Sávlön, featuring bass player Maria Sullivan and drummer Adam Brodigan beside Yüceil and Hodgson. They released a self-titled EP in 2010, followed by ''Management'' in 2013. Shortly after the release of ''Management'', Sullivan and Brodigan left the band to start a family and focus on other musical projects, respectively. They were replaced by Dave Jackson and Blake Mostyn respectively, both friends of the band. Delta Sleep released their first full-length album ''Twin Galaxies'' in January 2015. ''Ghost City'', ''Younger Years'' and ''Soft Sounds'' (2018-2021) Their second full-length al ...
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Labyrinthine Fistula
A labyrinthine fistula is an abnormal opening in the inner ear. This can result in leakage of the perilymph into the middle ear. This includes specifically a perilymph fistula (PLF), an abnormal connection between the fluid of the inner ear and the air-filled middle ear. This is caused by a rupture of the round window or oval window ligaments separating the inner and middle ear. Another type of labyrinthine fistula is the superior semicircular canal dehiscence, which allows the inner ear to be influenced by the intracranial pressure directly. Signs and symptoms PLF usually induces one or all the following pathological states: aural fullness, fluctuating or non-fluctuating hearing loss, tinnitus and dizziness, which may sometimes include vertigo and balance disorders. Causes Labyrinthine fistula can be both congenital or develop over time with the thinning of the otic capsule by the persistent pulsations of the intracranial pressures against the bones of the skull. Finally, medic ...
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Membranous Labyrinth
The membranous labyrinth is a collection of fluid filled tubes and chambers in the inner ear The inner ear (internal ear, auris interna) is the innermost part of the vertebrate ear. In vertebrates, the inner ear is mainly responsible for sound detection and balance. In mammals, it consists of the bony labyrinth, a hollow cavity in the ... which contain the receptors for the senses of equilibrium and hearing. It is lodged within the bony labyrinth and has the same general form; it is, however, considerably smaller and is partly separated from the bony walls by a quantity of fluid, the perilymph. In certain places, it is fixed to the walls of the cavity. The membranous labyrinth contains fluid called endolymph. The walls of the membranous labyrinth are lined with distributions of the cochlear nerve, one of the two branches of the vestibulocochlear nerve. The other branch is the vestibular nerve. Within the vestibule, the membranous labyrinth does not quite preserve th ...
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Eustachian Tube
The Eustachian tube (), also called the auditory tube or pharyngotympanic tube, is a tube that links the nasopharynx to the middle ear, of which it is also a part. In adult humans, the Eustachian tube is approximately long and in diameter. It is named after the sixteenth-century Italian anatomist Bartolomeo Eustachi. In humans and other tetrapods, both the middle ear and the ear canal are normally filled with air. Unlike the air of the ear canal, however, the air of the middle ear is not in direct contact with the atmosphere outside the body; thus, a pressure difference can develop between the atmospheric pressure of the ear canal and the middle ear. Normally, the Eustachian tube is collapsed, but it gapes open with swallowing and with positive pressure, allowing the middle ear's pressure to adjust to the atmospheric pressure. When taking off in an aircraft, the ambient air pressure goes from higher (on the ground) to lower (in the sky). The air in the middle ear expands as ...
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Middle Ear
The middle ear is the portion of the ear medial to the eardrum, and distal to the oval window of the cochlea (of the inner ear). The mammalian middle ear contains three ossicles (malleus, incus, and stapes), which transfer the vibrations of the eardrum into waves in the fluid and membranes of the inner ear. The hollow space of the middle ear is also known as the tympanic cavity and is surrounded by the tympanic part of the temporal bone. The auditory tube (also known as the Eustachian tube or the pharyngotympanic tube) joins the tympanic cavity with the nasal cavity ( nasopharynx), allowing pressure to equalize between the middle ear and throat. The primary function of the middle ear is to efficiently transfer acoustic energy from compression waves in air to fluid–membrane waves within the cochlea. Structure Ossicles The middle ear contains three tiny bones known as the ossicles: '' malleus'', ''incus'', and '' stapes''. The ossicles were given their Latin names f ...
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Temporal Lobe
The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. ''Temporal'' refers to the head's temples. Structure The temporal lobe consists of structures that are vital for declarative or long-term memory. Declarative (denotative) or explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events). The medial temporal lobe structures are critical for long-term memory, and include the hippocampal formation, perirhinal cortex, parahippocampal, and entorhinal neocortical regions. The hippocampus is critical for memory formation, and the surrounding medial temporal cortex is currently theorized to be critical f ...
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Epileptic Seizure
A seizure is a sudden, brief disruption of brain activity caused by abnormal, excessive, or synchronous neuronal firing. Depending on the regions of the brain involved, seizures can lead to changes in movement, sensation, behavior, awareness, or consciousness. Symptoms vary widely. Some seizures involve subtle changes, such as brief lapses in attention or awareness (as seen in absence seizures), while others cause generalized convulsions with loss of consciousness ( tonic–clonic seizures). Most seizures last less than two minutes and are followed by a postictal period of confusion, fatigue, or other symptoms. A seizure lasting longer than five minutes is a medical emergency known as status epilepticus. Seizures are classified as provoked, when triggered by a known cause such as fever, head trauma, or metabolic imbalance, or unprovoked, when no immediate trigger is identified. Recurrent unprovoked seizures define the neurological condition epilepsy. Clinical features Seizure ...
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Brainstem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating heart and respiratory system, respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the b ...
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