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Euphoric
Euphoria ( ) is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. Certain natural rewards and social activities, such as aerobic exercise, laughter, listening to or making music and dancing, can induce a state of euphoria. Euphoria is also a symptom of certain neurological or neuropsychiatric disorders, such as mania. Romantic love and components of the human sexual response cycle are also associated with the induction of euphoria. Certain drugs, many of which are addictive, can cause euphoria, which at least partially motivates their recreational use. Hedonic hotspots – i.e., the pleasure centers of the brain – are functionally linked. Activation of one hotspot results in the recruitment of the others. Inhibition of one hotspot results in the blunting of the effects of activating another hotspot. Therefore, the simultaneous activation of every hedonic hotspot within the reward system is believed to be ne ...
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Mania
Mania, also known as manic syndrome, is a Psychiatry, psychiatric Abnormality (behavior), behavioral syndrome defined as a state of Abnormality (behavior), abnormally elevated arousal, affect (psychology), affect, and energy level. During a manic episode, an individual will experience Emotional lability, rapidly changing emotions and moods, highly influenced by surrounding Stimulus (psychology), stimuli. Although mania is often conceived of as a "mirror image" to depression (mood), depression, the heightened mood (psychology), mood can be Dysphoria, dysphoric as well as Euphoria, euphoric. As the mania intensifies, irritability can be more pronounced and result in anxiety or anger. The symptoms of mania include elevated mood (either euphoric or irritable), Flight of Ideas, flight of ideas, pressure of speech, increased energy, decreased "need" and desire for sleep, and psychomotor agitation, hyperactivity. They are most plainly evident in fully developed hypomanic states, however ...
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Cocaine
Cocaine is a tropane alkaloid and central nervous system stimulant, derived primarily from the leaves of two South American coca plants, ''Erythroxylum coca'' and ''Erythroxylum novogranatense, E. novogranatense'', which are cultivated almost exclusively in the Andes. Indigenous peoples of South America, Indigenous South Americans have traditionally used coca leaves for over a thousand years. Notably, there is no evidence that habitual coca leaf use causes addiction or withdrawal, unlike cocaine. Medically, cocaine is rarely employed, mainly as a topical medication under controlled settings, due to its high abuse potential, adverse effects, and expensive cost. Despite this, recreational drug use, recreational use is widespread, driven by its euphoric and aphrodisiac properties. Levamisole induced necrosis syndrome (LINES)-a complication of the common cocaine Lacing (drugs), cutting agent levamisole-and prenatal cocaine exposure is particularly harmful. Street cocaine is ...
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Addiction
Addiction is a neuropsychological disorder characterized by a persistent and intense urge to use a drug or engage in a behavior that produces natural reward, despite substantial harm and other negative consequences. Repetitive drug use can alter brain function in synapses similar to natural rewards like food or falling in love in ways that perpetuate craving and weakens self-control for people with pre-existing vulnerabilities. This phenomenon – drugs reshaping brain function – has led to an understanding of addiction as a brain disorder with a complex variety of psychosocial as well as neurobiological factors that are implicated in the development of addiction. While mice given cocaine showed the compulsive and involuntary nature of addiction, for humans this is more complex, related to behavior or personality traits. Classic signs of addiction include compulsive engagement in rewarding stimuli, ''preoccupation'' with substances or behavior, and continued use des ...
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Human Sexual Response Cycle
The human sexual response cycle is a four-stage model of physiological responses to sexual stimulation, which, in order of their occurrence, are the excitement, plateau, orgasmic, and resolution phases. This physiological response model was first formulated by William H. Masters and Virginia E. Johnson, in their 1966 book ''Human Sexual Response''. Since that time, other models regarding human sexual response have been formulated by several scholars who have criticized certain inaccuracies in the human sexual response cycle model. Excitement phase The excitement phase (also known as the arousal phase or initial excitement phase) is the first stage of the human sexual response cycle, which occurs as a result of physical or mental erotic stimuli, such as kissing, making out, fantasizing or viewing erotic images, that leads to sexual arousal. During this stage, the body prepares for sexual intercourse, initially leading to the plateau phase. There is wide socio-cultural variati ...
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Supreme Happiness
Supreme may refer to: Entertainment * Supreme (character), a comic book superhero created by Rob Liefeld * Supreme (film), ''Supreme'' (film), a 2016 Telugu film * Supreme (producer), hip-hop record producer * Supreme (song), "Supreme" (song), a 2000 song by Robbie Williams * The Supremes, Motown-era singer group * Supreme Pictures Corporation, 1930s film company Other * Supreme (brand), a clothing brand based in New York * Supreme (cookery), a term used in cookery * Supreme, Louisiana, a census-designated place in the United States * Supreme Soviet, the highest legislation body of Soviet Union, dissolved in 1991 * Oldsmobile Cutlass Supreme, car produced by Oldsmobile between 1966 and 1997 * Plaxton Supreme, British coach bodywork built in the late 1970s and early 1980s See also

* Supreme Records (other), several record labels * Supremo (other) * Supreme court * Supremacy (other) {{disambiguation ...
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Robert Scott (philologist)
Robert Scott (26 January 1811 – 2 December 1887) was a British academic philologist and Church of England priest. He is best known for co-authoring the Greek-English Lexicon, commonly known as Liddell and Scott, which is still in use today. Scott was also a professor of Greek at the University of Oxford for over thirty years before his death on 2 December 1887. Biography Scott was born on 26 January 1811 in Bondleigh, Devon, England. He was educated at St Bees School in Cumbria, and Shrewsbury School in Shropshire. He studied classics at Christ Church, Oxford, graduating with a Bachelor of Arts (BA) degree in 1833. Scott was ordained in 1835 and held the college living of Duloe, Cornwall, from 1845 to 1850. He was a prebendary of Exeter Cathedral from 1845 to 1866 and rector of South Luffenham, Rutland, from 1850 to 1854 when he was elected Master of Balliol College, Oxford. He served as Dean Ireland's Professor of the Exegesis of Holy Scripture at Oxford from 1861 to ...
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Henry Stuart Jones
Sir Henry Stuart Jones, FBA (15 May 1867 – 29 June 1939) was a British academic. He was educated at Balliol College, Oxford; he obtained a First in Classical Moderations in 1888 and a First in Literae Humaniores ('Greats', a combination of philosophy and ancient history) in 1890. He was appointed to a Fellowship at Trinity College, Oxford, in 1897. From 1903 to 1905 he was Director of the British School at Rome and, in 1920, moved from Trinity to Brasenose College to take up the post of Camden Professor of Ancient History which he held until 1927 when he took up a series of Welsh academic posts listed below. Originally, Stuart was his second forename, but he and his wife generally prefixed it to their surname, and he was knighted in 1933 under the name Stuart-Jones. Career He attended the British School at Athens and later served as director of the British School at Rome. For Oxford University Press, Stuart Jones edited Thucydides' ''Historiae'', the history of the Pelop ...
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Opposite (semantics)
In lexical semantics, opposites are words lying in an inherently incompatible binary relationship. For example, something that is ''even'' entails that it is not ''odd''. It is referred to as a 'binary' relationship because there are two members in a set of opposites. The relationship between opposites is known as opposition. A member of a pair of opposites can generally be determined by the question: "What is the opposite of ''X''" The term antonym (and the related antonymy) is commonly taken to be synonymous with opposite, but antonym also has other more restricted meanings. Graded (or gradable) antonyms are word pairs whose meanings are opposite and which lie on a continuous spectrum (''hot'', ''cold''). Complementary antonyms are word pairs whose meanings are opposite but whose meanings do not lie on a continuous spectrum (''push'', ''pull''). Relational antonyms are word pairs where opposite makes sense only in the context of the relationship between the two meanings (''teache ...
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The New World Of English Words
''The New World of English Words, or, a General Dictionary'' is an English dictionary compiled by Edward Phillips and first published in London in 1658. It was the first folio English dictionary. Contents As well as containing common words, the dictionary featured many unusual words, foreign terms, proper nouns and other specialist terms. In total, the original edition featured 11,000 entries, increasing to 17,000 by the fifth edition in 1696. It was later revised and enlarged by John Kersey in 1706, eventually containing 38,000 entries. Kersey had already compiled his own dictionary, ''A New English Dictionary'', in 1702, and used this revised edition of '' The New World of English Words'' as the basis for his more concise ''Dictionarium Anglo-Britannicum'' in 1708. Plagiarism At least half of the entries were copied directly, without permission, from Thomas Blount's '' Glossographia'', which had been published a couple of years before. Blount responded by publishing ''A wor ...
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Dysphoria
Dysphoria (; ) is a profound state of unease or dissatisfaction. It is the semantic opposite of euphoria. In a psychiatric context, dysphoria may accompany depression, anxiety, or agitation. In psychiatry Intense states of distress and unease increase the risk of suicide, as well as being unpleasant in themselves. Relieving dysphoria is therefore a priority of psychiatric treatment. One may treat underlying causes such as depression (especially dysthymia or major depressive disorder) or bipolar disorder as well as the dysphoric symptoms themselves. The 11th revision of the ''International Classification of Diseases'' (ICD-11) defines dysphoria as "an unpleasant mood state, which can include feelings of depression, anxiety, discontent, irritability, and unhappiness." Dissatisfaction with being able-bodied can be diagnosed as body integrity dysphoria in the ICD-11. Gender dysphoria Gender dysphoria is discomfort, unhappiness or distress due to the primary and secondary ...
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Thomas Laycock (physiologist)
Thomas Laycock FRSE FRCPE (10 August 1812 – 21 September 1876) was an English physician and neurophysiologist who was a native of Bedale near York. Among medical historians, he is best known for his influence on John Hughlings Jackson and the psychiatrist James Crichton-Browne. Laycock's interests were the nervous system and psychology; he is known as one of the founders of physiological psychology. He was the first to formulate the concept of reflex action within the brain, and is also known for his classification of mental illnesses. Life Laycock was born on 10 August 1812 in Wetherby, Yorkshire, and was the son of Wesleyan minister Rev Thomas Laycock. He attended the Woodhouse Grove School, Wesleyan Academy on Woodhouse Grove in West Yorkshire. At the age of fifteen, Laycock trained as an apprentice surgeon-apothecary under a Mr. Spence. He went on to study at the University College London, University College in London and furthered his training in Paris in 1834 for two ...
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