Engineering Biology
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Engineering Biology
Engineering biology is the set of methods for designing, building, and testing engineered biological systems which have been used to manipulate information, construct materials, process chemicals, produce energy, provide food, and help maintain or enhance human health and environment. History Rapid advances in the ability to genetically modify biological organisms have advanced a new engineering discipline, commonly referred to as synthetic biology. This approach seeks to harness the power of living systems for a variety of manufacturing applications, such as advanced therapeutics, sustainable Sustainability is a social goal for people to co-exist on Earth over a long period of time. Definitions of this term are disputed and have varied with literature, context, and time. Sustainability usually has three dimensions (or pillars): env ... fuels, chemical feedstocks, and advanced materials. To date, research in synthetic biology has typically relied on trial-and-error approache ...
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Biological System
A biological system is a complex Biological network inference, network which connects several biologically relevant entities. Biological organization spans several scales and are determined based different structures depending on what the system is. Examples of biological systems at the macro scale are populations of organisms. On the organ (anatomy), organ and Tissue (biology), tissue scale in mammals and other animals, examples include the circulatory system, the respiratory system, and the nervous system. On the Micrometre, micro to the Nanometre, nanoscopic scale, examples of biological systems are cell (biology), cells, organelles, macromolecular complexes and Regulatory T cell, regulatory pathways. A biological system is not to be confused with a Living systems, living system, such as a living organism. Organ and tissue systems These specific systems are widely studied in human anatomy and are also present in many other animals. * Respiratory system: the organs used for b ...
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Genetic Engineering
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of Genetic engineering techniques, technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by Artificial gene synthesis, artificially synthesising the DNA. A Vector (molecular biology), construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the Lambda phage, lambda virus. As well as inserting genes, the process can be used to remove, or "Gene knockout, knock out", genes. The new DNA can either be inserted randomly or Gene targeting, targeted to a spe ...
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Synthetic Biology
Synthetic biology (SynBio) is a multidisciplinary field of science that focuses on living systems and organisms. It applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biochemistry, biotechnology, biomaterials, Materials science, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, Model lipid bilayer, membrane science, biophysics, Biological engineering, chemical and biological engineering, Electrical engineering, electrical and computer engineering, control engineering and evolutionary biology. It includes designing and constructing BioBrick, biological modules, biological systems, and biological machines, or re-designing existing biological systems for useful purposes. Additionally, it is the branch of science that focuses on the ne ...
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Sustainability
Sustainability is a social goal for people to co-exist on Earth over a long period of time. Definitions of this term are disputed and have varied with literature, context, and time. Sustainability usually has three dimensions (or pillars): environmental, economic, and social. Many definitions emphasize the environmental dimension. This can include addressing key environmental problems, including climate change and biodiversity loss. The idea of sustainability can guide decisions at the global, national, organizational, and individual levels. A related concept is that of sustainable development, and the terms are often used to mean the same thing. UNESCO distinguishes the two like this: "''Sustainability'' is often thought of as a long-term goal (i.e. a more sustainable world), while ''sustainable development'' refers to the many processes and pathways to achieve it." Details around the economic dimension of sustainability are controversial. Scholars have discussed this under ...
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Biotechnology
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and con ...
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Molecular Genetics
Molecular genetics is a branch of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens.  The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology. It integrates these disciplines to explore things like genetic inheritance, gene regulation and expression, and the molecular mechanism behind various life processes. A key goal of molecular genetics is to identify and study genetic mutations. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Therefore molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid th ...
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Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. This multifaceted research domain necessitates the collaborative efforts of chemists, biologists, mathematicians, physicists, and engineers to decipher the biology of intricate living systems by merging various quantitative molecular measurements with carefully constructed mathematical models. It represents a comprehensive method for comprehending the complex relationships within biological systems. In contrast to conventional biological studies that typically center on isolated elements, systems biology seeks to combine different biological data to create models that illustrate and elucidate the dynamic interactions with ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field of science that develops methods and Bioinformatics software, software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics uses biology, chemistry, physics, computer science, data science, computer programming, information engineering, mathematics and statistics to analyze and interpret biological data. The process of analyzing and interpreting data can sometimes be referred to as computational biology, however this distinction between the two terms is often disputed. To some, the term ''computational biology'' refers to building and using models of biological systems. Computational, statistical, and computer programming techniques have been used for In silico, computer simulation analyses of biological queries. They include reused specific analysis "pipelines", particularly in the field of genomics, such as by the identification of genes and single nucleotide polymorphis ...
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Synthetic Biology
Synthetic biology (SynBio) is a multidisciplinary field of science that focuses on living systems and organisms. It applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biochemistry, biotechnology, biomaterials, Materials science, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, Model lipid bilayer, membrane science, biophysics, Biological engineering, chemical and biological engineering, Electrical engineering, electrical and computer engineering, control engineering and evolutionary biology. It includes designing and constructing BioBrick, biological modules, biological systems, and biological machines, or re-designing existing biological systems for useful purposes. Additionally, it is the branch of science that focuses on the ne ...
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Biocybernetics
Biocybernetics is the application of cybernetics to biological science disciplines such as neurology and multicellular systems. Biocybernetics plays a major role in systems biology, seeking to integrate different levels of information to understand how biological systems function. The field of cybernetics itself has origins in biological disciplines such as neurophysiology. Biocybernetics is an abstract science and is a fundamental part of theoretical biology, based upon the principles of systemics. Biocybernetics is a psychological study that aims to understand how the human body functions as a biological system and performs complex mental functions like thought processing, motion, and maintaining homeostasis. Within this field, many distinct qualities allow for different distinctions within the cybernetic groups such as humans and insects such as beehives and ants. Humans work together but they also have individual thoughts that allow them to act on their own, while worker bees ...
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Appropriate Technology
Appropriate technology is a movement (and its manifestations) encompassing technology, technological choice and application that is small-scale, affordable by its users, labor-intensive, efficient energy use, energy-efficient, environmentally sustainable, and localism (politics), locally autonomous. It was originally articulated as intermediate technology by the economist E. F. Schumacher, Ernst Friedrich "Fritz" Schumacher in his work ''Small Is Beautiful.'' Both Schumacher and many modern-day proponents of appropriate technology also emphasize the technology as People-centered development, people-centered. Appropriate technology has been used to address issues in a wide range of fields. Well-known examples of appropriate technology applications include: bike- and hand-powered water pumps (and other self-powered equipment), the bicycle, the universal nut sheller, self-contained solar lamps and Solar street light, streetlights, and passive solar building designs. Today appropriate ...
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