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Elemicin
Elemicin is a phenylpropene, a natural organic compound, and is a constituent of several plant species' essential oils. Natural occurrence Elemicin is a constituent of the oleoresin and the essential oil of '' Canarium luzonicum'' (also referred to as elemi). Elemicin is named after this tree. One study found it to compose 2.4% of the fresh essential oil. Elemicin is also present in the oils of the spices nutmeg and mace, with it composing 2.4% and 10.5% of those oils respectively. Structurally, elemicin is similar to myristicin, differing only by myristicin's methyl group that joins the two oxygen atoms that make up its dioxymethy moiety, with both constituents being found in nutmeg and mace. Isolation Elemicin was first isolated from elemi oil using vacuum distillation. Specifically, the substance was collected between 162-165 °C at a reduced pressure of 10 torr. Preparation Elemicin has been synthesized from syringol and allyl bromide using Williamson ether syn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myristicin
Myristicin is a naturally occurring compound (an allylbenzene) found in common herbs and spices such as nutmeg. It is an insecticide, and has been shown to enhance the effectiveness of other insecticides. When ingested in high doses, myristicin may produce hallucinogenic effects, and can be converted to MMDMA in controlled chemical synthesis. It interacts with many enzymes and signaling pathways in the body, and may have dose-dependent cytotoxicity in living cells. Myristicin is listed in the Hazardous Substances Data Bank. Uses Isolated myristicin has proven an effective insecticide against many agricultural pests, including ''Aedes aegypti'' mosquito larvae, '' Spilosoma obliqua'' (hairy caterpillars), ''Epilachna varivestis'' ( Mexican bean beetles), ''Acyrthosiphon pisum'' (pea aphids), mites, and ''Drosophila melanogaster'' (fruit flies). Myristicin was shown to be an effective repellent, and to cause mortality via direct and systemic exposure. It also displayed a syner ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nutmeg Oil
Nutmeg oil is a volatile essential oil from nutmeg (''Myristica fragrans''). The oil is colorless or light yellow and smells and tastes of nutmeg. It contains numerous components of interest to the oleochemical industry. The essential oil consists of approximately 90% terpene hydrocarbons. Prominent components are sabinene, α-pinene, β-pinene, and limonene. A major oxygen-containing component is terpinen-4-ol. The oil also contains small amounts of various phenolic compounds and aromatic ethers, e.g. myristicin, elemicin, safrole, and methyl eugenol. The phenolic fraction is considered main contributor to the characteristic nutmeg odor. However, in spite of the low oil content, the characteristic composition of nutmeg oil makes it a valuable product for food, cosmetic and pharmaceutical industries. Therefore, an improved process for its extraction would be of industrial interest. General uses The essential oil is obtained by the steam distillation of ground nutmeg and is u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mescaline
Mescaline, also known as mescalin or mezcalin, and in chemical terms 3,4,5-trimethoxyphenethylamine, is a natural product, naturally occurring psychedelic drug, psychedelic alkaloid, protoalkaloid of the substituted phenethylamine class, found in Cactus, cacti like peyote (''Lophophora williamsii'') and San Pedro cactus, San Pedro (certain species of the Echinopsis genus) and known for its Serotonin, serotonergic Hallucinogen, hallucinogenic effects. Mescaline is typically taken orally and used recreationally, spiritually, and medically, with psychedelic effects occurring at doses from 100 to 1,000 mg, including microdosing below 75 mg, and it can be consumed in pure form or via mescaline-containing cacti. Mescaline induces a psychedelic experience characterized by vivid visual patterns, altered perception of time and self, synesthesia, and spiritual effects, with an onset of 0.5–0.9 hours and a duration that increases with dose, ranging from about 6 to 14 hours. Mescaline h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canarium Luzonicum
''Canarium luzonicum'', commonly known as elemi, is a tree native to the Philippines. The oleoresin harvested from it is also known as elemi resin. Synonyms * ''Canarium carapifolium'' G.Perkins * ''Canarium oliganthum'' Merr. * ''Canarium polyanthum'' G.Perkins * ''Canarium triandrum'' Engl. * ''Pimela luzonica'' Blume Description ''Canarium luzonicum'' is a large evergreen tree growing to a maximum height of about . The leaves are alternate and are pinnate. Clusters of flowers, which are pollinated by insects, are followed by thick-shelled nuts with edible kernels. Uses Elemi resin is a pale yellow substance, of honey-like consistency. Aromatic elemi oil is steam distilled from the resin. It is a fragrant resin with a sharp pine and lemon-like scent. One of the resin components is called amyrin. Elemi resin is chiefly used commercially in varnishes and lacquers, and certain printing inks. It is used as a herbal medicine to treat bronchitis, catarrh, extreme coughin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nutmeg
Nutmeg is the seed, or the ground spice derived from the seed, of several tree species of the genus '' Myristica''; fragrant nutmeg or true nutmeg ('' M. fragrans'') is a dark-leaved evergreen tree cultivated for two spices derived from its fruit: nutmeg, from its seed, and mace, from the seed covering. It is also a commercial source of nutmeg essential oil and nutmeg butter. Maluku's Banda Islands are the main producer of nutmeg and mace, and the true nutmeg tree is native to the islands. Nutmeg and mace, commonly used as food spices, have been traditionally employed for their psychoactive and aphrodisiac effects, though clinical evidence is lacking. High doses can cause serious toxic effects including acute psychosis, with risks heightened during pregnancy and with psychiatric conditions. Conifers of the genus '' Torreya'', commonly known as the nutmeg yews, have edible seeds of similar appearance, but are not closely related to ''M. fragrans'', and are not used as a spice ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deliriant
Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics such as LSD and dissociatives such as ketamine, due to their primary effect of causing delirium, as opposed to the more lucid and less disturbed states produced by other types of hallucinogens, where rational thought is better preserved (including the ability to distinguish hallucinations from reality). Duncan, D. F., and Gold, R. S. (1982). Drugs and the Whole Person. New York: John Wiley & Sons The term generally refers to anticholinergic drugs, which are substances that inhibit the function of the neurotransmitter acetylcholine. Common examples of deliriants include plants of the genera ''Datura'' and '' Brugmansia'', both containing scopolamine, as well as higher than recommended dosages of diphenhydramine (Benadryl). A number of plant deliriants such as that of the Solanaceae family, particularly in the Americas, have been used by some indi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylpropene
Phenylpropenes broadly are compounds containing a phenyl ring bonded to propene, more specifically those with an allyl group bonded to a benzene ring, having the parent structure of allylbenzene. These comprise a class of phenylpropanoids, where there are typically other substituents In organic chemistry, a substituent is one or a group of atoms that replaces (one or more) atoms, thereby becoming a moiety (chemistry), moiety in the resultant (new) molecule. The suffix ''-yl'' is used when naming organic compounds that conta ... bonded to the aromatic ring. Phenylpropene specifically may refer to the following isomers of C9H10 (molar mass 118.179 g/mol): * ''trans''-Propenylbenzene (''trans''-1-phenylpropene) * α-Methylstyrene (2-phenylpropene) * Allylbenzene (3-phenylpropene) {{Chemindex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anticholinergic
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central nervous system, central and peripheral nervous system. These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of Smooth muscle tissue, smooth muscles present in the gastrointestinal tract, urinary tract, lungs, sweat glands, and many other parts of the body. In broad terms, anticholinergics are divided into two categories in accordance with their specific targets in the central and peripheral nervous system and at the neuromuscular junction: antimuscarinic agents and antinicotinic agents (ganglionic blockers, neuromuscular blockers). The term "anticholinergic" is typically used to refer to antimuscarinics that competitively inhibit the binding of ACh to muscarinic a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
5-HT2A Receptor
The 5-HT2A receptor is a subtype of the 5-HT2 receptor, 5-HT2 receptor that belongs to the serotonin receptor family and functions as a GPCR, G protein-coupled receptor (GPCR). It is a cell surface receptor that activates multiple intracellular signalling cascades. Like all 5-HT2 receptors, the 5-HT2A receptor is coupled to the Gq protein, Gq/G11 signaling pathway. It is the primary excitatory receptor subtype among the serotonin-responsive GPCRs. The 5-HT2A receptor was initially noted for its central role as the primary target of serotonergic psychedelic drugs such as LSD and psilocybin mushrooms. It later regained research prominence when found to mediate, at least in part, the effects of many antipsychotic drugs, particularly atypical antipsychotic, atypical antipsychotics. Downregulation of post-synaptic 5-HT2A receptors is an adaptive response triggered by chronic administration of selective serotonin reuptake inhibitors (SSRIs) and atypical antipsychotics. Elevated 5-HT2A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylpropenes
Phenylpropenes broadly are compounds containing a phenyl ring bonded to propene, more specifically those with an allyl group bonded to a benzene ring, having the parent structure of allylbenzene. These comprise a class of phenylpropanoids, where there are typically other substituents bonded to the aromatic ring. Phenylpropene specifically may refer to the following isomers of C9H10 (molar mass 118.179 g/mol): * ''trans''-Propenylbenzene (''trans''-1-phenylpropene) * α-Methylstyrene (2-phenylpropene) *Allylbenzene Allylbenzene or 3-phenylpropene is an organic compound with the formula C6H5CH2CH=CH2. It is a colorless liquid. The compound consists of a phenyl group attached to an allyl group. Allylbenzene isomerizes to trans-propenylbenzene. In plant bioc ... (3-phenylpropene) {{Chemindex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
