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Eicosatrienoic Acid
Eicosatrienoic acid (or icosatrienoic acid) may refer to: * Dihomo-γ-linolenic acid, (8''Z'',11''Z'',14''Z'')-eicosatrienoic acid * Mead acid, (5''Z'',8''Z'',11''Z'')-eicosatrienoic acid * Sciadonic acid, (5''Z'',11''Z'',14''Z'')-eicosatrienoic acid See also * Epoxyeicosatrienoic acid {{chemistry disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dihomo-γ-linolenic Acid
Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω−6 fatty acid. (also called, cis,cis,cis-8,11,14-Eicosatrienoic acid) In physiological literature, it is given the name 20:3 (ω−6). DGLA is a carboxylic acid with a 20-carbon chain and three '' cis'' double bonds; the first double bond is located at the sixth carbon from the omega end. DGLA is the elongation product of γ-linolenic acid (GLA; 18:3, ω−6). GLA, in turn, is a desaturation product (Delta 6 desaturase) of linoleic acid (18:2, ω−6). DGLA is made in the body by the elongation of GLA, by an efficient enzyme which does not appear to suffer any form of (dietary) inhibition. DGLA is an extremely uncommon fatty acid, found only in trace amounts in animal products. Biological effects The eicosanoid metabolites of DGLA are: * Series-1 thromboxanes (thromboxanes with 1 double-bond), via the COX-1 and COX-2 pathways. * Series-1 prostanoids, via the COX-1 and COX-2 pathways. * A 15-hydroxyl derivative that blocks ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mead Acid
Mead acid is an omega-9 fatty acid, first characterized by James F. Mead. As with some other omega-9 polyunsaturated fatty acids, animals can make Mead acid ''de novo''. Its elevated presence in the blood is an indication of essential fatty acid deficiency. Mead acid is found in large quantities in cartilage. Chemistry Mead acid, also referred to as eicosatrienoic acid, is chemically a carboxylic acid with a 20-carbon chain and three methylene-interrupted '' cis'' double bonds, as is typical for polyunsaturated fatty acids. The first double bond is located at the ninth carbon from the omega end. In physiological literature, it is given the name 20:3 (n-9). (See Fatty Acid#Nomenclature for an explanation of the naming system.) In the presence of lipoxygenase, cytochrome p450, or cyclooxygenase, mead acid can form various hydroxyeicosatetraenoic acid (HETE) and hydroperoxy (HpETE) products. Physiology Two fatty acids, linoleic acid and alpha-linolenic acid, are consi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sciadonic Acid
Sciadonic acid, also known as eicosatrienoic acid, is a polyunsaturated fatty acid. In regard to its structure, 5''Z'',11''Z'',14''Z''-eicosa-5,11,14-trienoic acid (sciadonic acid) has 3 double bonds in the 5, 11, and 14 positions all of which are in the ''cis'' configuration. It is further classified as Δ5-fatty, and an omega-6 acid due to the methylene interrupted double bond at carbon-5 and a final double bond 6 carbons away from the methylene tail of the hydrocarbon. Sciadonic acid is a naturally occurring compound and has been found to play a role as a plant metabolite, commonly found in pine nut oil. Furthermore, there have been propositions of several health applications for sciadonic acid as an anti-inflammatory agent. Sharing close structural similarity to arachidonic acid, sciadonic acid acts as a replacement phospholipid in the corresponding biochemical pathways. Etymology The root behind the nomenclature of sciadonic acid comes from its high abundance in the seed, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |