|
Dragomabin
Dragomabin is a lipopeptide isolated from the marine cyanobacteria '' Lyngbya majuscula''. It has ''in vitro ''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in ...'' antimalarial activity. In 2018, a laboratory synthesis of dragomabin was reported. The synthesis identified a misassignment of the configuration of the stereogenic center on the alkyne-bearing fragment and it was revised from (''S'') to (''R''). References Lipopeptides {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lyngbya Majuscula
''Lyngbya majuscula'' is a species of filamentous cyanobacteria in the genus '' Lyngbya''. It is named after the Dane Hans Christian Lyngbye. As a result of recent genetic analyses, several new genera were erected from the genus ''Lyngbya'': ''e.g.'', '' Moorea'', '' Limnoraphis'', '' Okeania'', '' Microseira'', and '' Dapis''. Several specimens identified as ''L. majuscula'' and collected in marine tropical regions are now classified as members of the genera ''Okeania'' and ''Moorea''. ''L. majuscula'' is the cause of seaweed dermatitis. Chemical constituents Almost 300 different secondary metabolites have been isolated from specimens identified as ''L. majuscula''. However, most of these studies lack a molecular identification of the samples. The toxins antillatoxin and kalkitoxin and the lipopeptide dragomabin have been isolated from ''L. majuscula''. Serinolamide A is a cannabinoid structurally related to anandamide Anandamide (ANA), also referred to as ''N''-arach ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipopeptide
A lipopeptide is a molecule consisting of a lipid connected to a peptide. They are able to self-assemble into different structures. Many bacteria produce these molecules as a part of their metabolism, especially those of the genus ''Bacillus'', ''Pseudomonas'' and '' Streptomyces''. Certain lipopeptides are used as antibiotics. Due to the structural and molecular properties such as the fatty acid chain, it poses the effect of weakening the cell function or destroying the cell. Other lipopeptides are toll-like receptor Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-pass membrane protein, single-spanning receptor (biochemistry), receptors usually expressed on sentinel cells such as macrophages ... agonists. Certain lipopeptides can have strong antifungal and hemolytic activities. It has been demonstrated that their activity is generally linked to interactions with the plasma membrane, and sterol components of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyanobacteria
Cyanobacteria ( ) are a group of autotrophic gram-negative bacteria that can obtain biological energy via oxygenic photosynthesis. The name "cyanobacteria" () refers to their bluish green (cyan) color, which forms the basis of cyanobacteria's informal common name, blue-green algae. Cyanobacteria are probably the most numerous taxon to have ever existed on Earth and the first organisms known to have produced oxygen, having appeared in the middle Archean eon and apparently originated in a freshwater or terrestrial environment. Their photopigments can absorb the red- and blue-spectrum frequencies of sunlight (thus reflecting a greenish color) to split water molecules into hydrogen ions and oxygen. The hydrogen ions are used to react with carbon dioxide to produce complex organic compounds such as carbohydrates (a process known as carbon fixation), and the oxygen is released as a byproduct. By continuously producing and releasing oxygen over billions of years, cyanobacte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, known as clinical trials, and whole plants. Definition ''In vitro'' (Latin language, Latin for "in glass"; often not italicized in English usage) studies are conducted ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
